| Neutrophils as early immunologic effectors in hemorrhage-or endotoxemia-induced acute lung injury E Abraham, A Carmody, R Shenkar, J Arcaroli American Journal of Physiology-Lung Cellular and Molecular Physiology 279 (6 …, 2000 | 562 | 2000 |
| Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome MD Schwartz, EE Moore, FA Moore, R Shenkar, P Moine, JB Haenel, ... Critical care medicine 24 (8), 1285-1292, 1996 | 445 | 1996 |
| Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity RA Stockton, R Shenkar, IA Awad, MH Ginsberg Journal of Experimental Medicine 207 (4), 881-896, 2010 | 361 | 2010 |
| Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling Z Zhou, AT Tang, WY Wong, S Bamezai, LM Goddard, R Shenkar, S Zhou, ... Nature 532 (7597), 122-126, 2016 | 284 | 2016 |
| Endothelial TLR4 and the microbiome drive cerebral cavernous malformations AT Tang, JP Choi, JJ Kotzin, Y Yang, CC Hong, N Hobson, R Girard, ... Nature 545 (7654), 305-310, 2017 | 282 | 2017 |
| Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury HK Yum, J Arcaroli, J Kupfner, R Shenkar, JM Penninger, T Sasaki, ... The Journal of Immunology 167 (11), 6601-6608, 2001 | 260 | 2001 |
| Biology of vascular malformations of the brain GG Leblanc, E Golanov, IA Awad, WL Young, ... Stroke 40 (12), e694-e702, 2009 | 258 | 2009 |
| Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance J Gault, H Sarin, NA Awadallah, R Shenkar, IA Awad Neurosurgery 55 (1), 1-17, 2004 | 240 | 2004 |
| NF-κB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome P Moine, R McIntyre, MD Schwartz, D Kaneko, R Shenkar, Y Le Tulzo, ... Shock 13 (2), 85-91, 2000 | 219 | 2000 |
| Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression. Y Le Tulzo, R Shenkar, D Kaneko, P Moine, G Fantuzzi, CA Dinarello, ... The Journal of clinical investigation 99 (7), 1516-1524, 1997 | 217 | 1997 |
| Early renal ischemia, with or without reperfusion, activates NFκB and increases TNF-α bioactivity in the kidney KK DONNAHOO, DR MELDRUM, R SHENKAR, CS CHUNG, ... The Journal of urology 163 (4), 1328-1332, 2000 | 215 | 2000 |
| Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-κB, and cyclic AMP response element binding protein R Shenkar, E Abraham The Journal of Immunology 163 (2), 954-962, 1999 | 206 | 1999 |
| Biallelic Somatic and Germ Line CCM1 Truncating Mutations in a Cerebral Cavernous Malformation Lesion J Gault, R Shenkar, P Recksiek, IA Awad Stroke 36 (4), 872-874, 2005 | 177 | 2005 |
| Hemorrhage activates myocardial NFκB and increases TNF-α in the heart DR Meldrum, R Shenkar, BC Sheridan, BS Cain, E Abraham, AH Harken Journal of Molecular and Cellular Cardiology 29 (10), 2849-2854, 1997 | 169 | 1997 |
| Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease DA McDonald, C Shi, R Shenkar, RA Stockton, F Liu, MH Ginsberg, ... Stroke 43 (2), 571-574, 2012 | 150 | 2012 |
| Interleukin 18 stimulates HIV type 1 in monocytic cells L Shapiro, AJ Puren, HA Barton, D Novick, RL Peskind, R Shenkar, Y Gu, ... Proceedings of the National Academy of Sciences 95 (21), 12550-12555, 1998 | 150 | 1998 |
| Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes. LM Shea, C Beehler, M Schwartz, R Shenkar, R Tuder, E Abraham Journal of immunology (Baltimore, Md.: 1950) 157 (9), 3902-3908, 1996 | 141 | 1996 |
| Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations R Shenkar, C Shi, T Rebeiz, RA Stockton, DA McDonald, AG Mikati, ... Genetics in medicine 17 (3), 188-196, 2015 | 137 | 2015 |
| A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease DA McDonald, R Shenkar, C Shi, RA Stockton, AL Akers, ... Human molecular genetics 20 (2), 211-222, 2011 | 135 | 2011 |
| Differential gene expression in human cerebrovascular malformations R Shenkar, JP Elliott, K Diener, J Gault, LJ Hu, RJ Cohrs, T Phang, ... Neurosurgery 52 (2), 465-478, 2003 | 135 | 2003 |
