| Polydopamine-based simple and versatile surface modification of polymeric nano drug carriers J Park, TF Brust, HJ Lee, SC Lee, VJ Watts, Y Yeo ACS nano 8 (4), 3347-3356, 2014 | 406 | 2014 |
| Biased agonism: An emerging paradigm in GPCR drug discovery Z Rankovic, TF Brust, LM Bohn Bioorganic & medicinal chemistry letters 26 (2), 241-250, 2016 | 283 | 2016 |
| Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria TF Brust, J Morgenweck, SA Kim, JH Rose, JL Locke, CL Schmid, L Zhou, ... Science signaling 9 (456), ra117-ra117, 2016 | 205 | 2016 |
| A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D1-like Dopamine Receptors JM Meyer, KFK Ejendal, LV Avramova, EE Garland-Kuntz, ... PLoS neglected tropical diseases 6 (1), e1478, 2012 | 99 | 2012 |
| Gαi/o-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later TF Brust, JM Conley, VJ Watts European journal of pharmacology 763, 223-232, 2015 | 67 | 2015 |
| Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties TF Brust, D Alongkronrusmee, M Soto-Velasquez, TA Baldwin, Z Ye, ... Science signaling 10 (467), eaah5381, 2017 | 57 | 2017 |
| Physiological roles of mammalian transmembrane adenylyl cyclase isoforms KF Ostrom, JE LaVigne, TF Brust, R Seifert, CW Dessauer, VJ Watts, ... Physiological Reviews 102 (2), 815-857, 2022 | 49 | 2022 |
| Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways TF Brust, MP Hayes, DL Roman, KD Burris, VJ Watts Journal of Pharmacology and Experimental Therapeutics 352 (3), 480-493, 2015 | 46 | 2015 |
| New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling TF Brust, MP Hayes, DL Roman, VJ Watts Biochemical pharmacology 93 (1), 85-91, 2015 | 39 | 2015 |
| Bisamidate Prodrugs of 2‐Substituted 9‐[2‐(Phosphonomethoxy) ethyl] adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis M Česnek, P Jansa, M Šmídková, H Mertlíková‐Kaiserová, M Dračínský, ... ChemMedChem 10 (8), 1351-1364, 2015 | 27 | 2015 |
| Palladium-catalyzed regio-and stereoselective γ-arylation of tertiary allylic amines: Identification of potent adenylyl cyclase inhibitors Z Ye, TF Brust, VJ Watts, M Dai Organic letters 17 (4), 892-895, 2015 | 27 | 2015 |
| Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analyses KFK Ejendal, JM Meyer, TF Brust, LV Avramova, CA Hill, VJ Watts Insect biochemistry and molecular biology 42 (11), 846-853, 2012 | 21 | 2012 |
| O6C-20-nor-salvinorin A is a stable and potent KOR agonist S Hirasawa, M Cho, TF Brust, JJ Roach, LM Bohn, RA Shenvi Bioorganic & medicinal chemistry letters 28 (16), 2770-2772, 2018 | 17 | 2018 |
| Hospital-associated methicillin-resistant Staphylococcus aureus carrying the PVL gene outbreak in a Public Hospital in Rio de Janeiro, Brazil T Brust, TM Costa, JC Amorim, MD Asensi, O Fernandes, F Aguiar-Alves Brazilian Journal of Microbiology 44, 865-868, 2013 | 16 | 2013 |
| Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications JM Conley, TF Brust, R Xu, KD Burris, VJ Watts JoVE (Journal of Visualized Experiments), e51218, 2014 | 13 | 2014 |
| Biased ligands at the kappa opioid receptor: fine-tuning receptor pharmacology TF Brust The Kappa Opioid Receptor, 115-135, 2020 | 12 | 2020 |
| Adenylyl cyclase 7 and neuropsychiatric disorders: a new target for depression? T Price, TF Brust Pharmacological Research 143, 106-112, 2019 | 11 | 2019 |
| Repurposing of a nucleoside scaffold from adenosine receptor agonists to opioid receptor antagonists DK Tosh, A Ciancetta, P Mannes, E Warnick, A Janowsky, AJ Eshleman, ... ACS omega 3 (10), 12658-12678, 2018 | 11 | 2018 |
| A selective adenylyl cyclase 1 inhibitor relieves pain without causing tolerance G Giacoletti, T Price, LVB Hoelz, AS Msdi, S Cossin, K Vazquez-Falto, ... Frontiers in Pharmacology 13, 2022 | 3 | 2022 |
| Adenylyl cyclase isoforms as potential drug targets TF Brust, RS Ostrom, VJ Watts Frontiers in Pharmacology 13, 1098240, 2022 | 2 | 2022 |
Val J WattsProfessor of Molecular Pharmacology, Purdue UniversityVerifierad e-postadress på purdue.edu
