Robert Slany
Robert Slany
Prof. LS Genetik, FAU Erlangen
Verified email at
Cited by
Cited by
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX–ENL
C Lavau, SJ Szilvassy, R Slany, ML Cleary
The EMBO journal 16 (14), 4226-4237, 1997
A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification
D Mueller, C Bach, D Zeisig, MP Garcia-Cuellar, S Monroe, A Sreekumar, ...
Blood, The Journal of the American Society of Hematology 110 (13), 4445-4454, 2007
The molecular biology of mixed lineage leukemia
RK Slany
Haematologica 94 (7), 984, 2009
Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization
BB Zeisig, T Milne, MP García-Cuéllar, S Schreiner, ME Martin, U Fuchs, ...
Molecular and cellular biology 24 (2), 617-628, 2004
Association of SET domain and myotubularin-related proteins modulates growth control
X Cui, ID Vivo, R Slany, A Miyamoto, R Firestein, ML Cleary
Nature genetics 18 (4), 331-337, 1998
The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation
M Birke, S Schreiner, MP García-Cuéllar, K Mahr, F Titgemeyer, RK Slany
Nucleic acids research 30 (4), 958-965, 2002
The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX
RK Slany, C Lavau, ML Cleary
Molecular and cellular biology 18 (1), 122-129, 1998
Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications
TA Milne, ME Martin, HW Brock, RK Slany, JL Hess
Cancer research 65 (24), 11367-11374, 2005
Misguided transcriptional elongation causes mixed lineage leukemia
D Mueller, MP García-Cuéllar, C Bach, S Buhl, E Maethner, RK Slany
PLoS biology 7 (11), e1000249, 2009
Dimerization of MLL fusion proteins immortalizes hematopoietic cells
ME Martin, TA Milne, S Bloyer, K Galoian, W Shen, D Gibbs, HW Brock, ...
Cancer cell 4 (3), 197-207, 2003
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia
X Jiang, H Huang, Z Li, Y Li, X Wang, S Gurbuxani, P Chen, C He, D You, ...
Cancer cell 22 (4), 524-535, 2012
Interaction of MLL amino terminal sequences with menin is required for transformation
C Caslini, Z Yang, M El-Osta, TA Milne, RK Slany, JL Hess
Cancer research 67 (15), 7275-7283, 2007
c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells
JL Hess, CB Bittner, DT Zeisig, C Bach, U Fuchs, A Borkhardt, J Frampton, ...
Blood 108 (1), 297-304, 2006
Leukemogenic transformation by HOXA cluster genes
C Bach, S Buhl, D Mueller, MP García-Cuéllar, E Maethner, RK Slany
Blood, The Journal of the American Society of Hematology 115 (14), 2910-2918, 2010
The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin
DT Zeisig, CB Bittner, BB Zeisig, MP García-Cuéllar, JL Hess, RK Slany
Oncogene 24 (35), 5525-5532, 2005
MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia
X Jiang, H Huang, Z Li, C He, Y Li, P Chen, S Gurbuxani, S Arnovitz, ...
Proceedings of the National Academy of Sciences 109 (47), 19397-19402, 2012
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia
F Zhou, Y Liu, C Rohde, C Pauli, D Gerloff, M Köhn, D Misiak, N Bäumer, ...
Nature cell biology 19 (7), 844-855, 2017
When epigenetics kills: MLL fusion proteins in leukemia
RK Slany
Hematological oncology 23 (1), 1-9, 2005
A new function of S-adenosylmethionine: the ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine
RK Slany, M Boesl, PF Crain, H Kersten
Biochemistry 32 (30), 7811-7817, 1993
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia
SC Monroe, SY Jo, DS Sanders, V Basrur, KS Elenitoba-Johnson, ...
Experimental hematology 39 (1), 77-86. e5, 2011
The system can't perform the operation now. Try again later.
Articles 1–20