A newly discovered class of human hematopoietic cells with SCID-repopulating activity M Bhatia, D Bonnet, B Murdoch, OI Gan, JE Dick Nature medicine 4 (9), 1038-1045, 1998 | 863 | 1998 |
Distinct routes of lineage development reshape the human blood hierarchy across ontogeny F Notta, S Zandi, N Takayama, S Dobson, OI Gan, G Wilson, ... Science 351 (6269), aab2116, 2016 | 844 | 2016 |
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ... Science 339 (6119), 543-548, 2013 | 843 | 2013 |
Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells K Takenaka, TK Prasolava, JCY Wang, SM Mortin-Toth, S Khalouei, ... Nature immunology 8 (12), 1313-1323, 2007 | 581 | 2007 |
Distinct classes of human stem cells that differ in proliferative and self-renewal potential G Guenechea, OI Gan, C Dorrell, JE Dick Nature immunology 2 (1), 75-82, 2001 | 392 | 2001 |
Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells F Mazurier, M Doedens, OI Gan, JE Dick Nature medicine 9 (7), 959-963, 2003 | 350 | 2003 |
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal M Milyavsky, OI Gan, M Trottier, M Komosa, O Tabach, F Notta, ... Cell stem cell 7 (2), 186-197, 2010 | 323 | 2010 |
Expansion of human cord blood CD34+CD38−cells in ex vivo culture during retroviral transduction without a corresponding increase in SCID repopulating cell … C Dorrell, OI Gan, DS Pereira, RG Hawley, JE Dick Blood, The Journal of the American Society of Hematology 95 (1), 102-110, 2000 | 307 | 2000 |
Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia M Chen, DJ Tomkins, W Auerbach, C McKerlie, H Youssoufian, L Liu, ... Nature genetics 12 (4), 448-451, 1996 | 290 | 1996 |
Assay of human stem cells by repopulation of NOD/SCID mice JE Dick, M Bhatia, O Gan, U Kapp, JCY Wang Stem Cells 15 (S2), 199-207, 1997 | 242 | 1997 |
Transduction of human CD34+ CD38-bone marrow and cord blood-derived SCID-repopulating cells with third-generation lentiviral vectors G Guenechea, OI Gan, T Inamitsu, C Dorrell, DS Pereira, M Kelly, ... Molecular Therapy 1 (6), 566-573, 2000 | 220 | 2000 |
Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment JL McKenzie, OI Gan, M Doedens, JCY Wang, JE Dick Nature immunology 7 (11), 1225-1233, 2006 | 201 | 2006 |
Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors, and long-term culture-initiating cells after incubation on human bone marrow … OI Gan, B Murdoch, A Larochelle, JE Dick Blood, The Journal of the American Society of Hematology 90 (2), 641-650, 1997 | 192 | 1997 |
Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells JL McKenzie, OI Gan, M Doedens, JE Dick Blood 106 (4), 1259-1261, 2005 | 180 | 2005 |
Lentivector-mediated clonal tracking reveals intrinsic heterogeneity in the human hematopoietic stem cell compartment and culture-induced stem cell impairment F Mazurier, OI Gan, JL McKenzie, M Doedens, JE Dick Blood 103 (2), 545-552, 2004 | 178 | 2004 |
Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin−CD34+CD38− population JL McKenzie, K Takenaka, OI Gan, M Doedens, JE Dick Blood 109 (2), 543-545, 2007 | 120 | 2007 |
Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage M Carreau, OI Gan, L Liu, M Doedens, C McKerlie, JE Dick, M Buchwald Blood, The Journal of the American Society of Hematology 91 (8), 2737-2744, 1998 | 108 | 1998 |
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells EL Bao, SK Nandakumar, X Liao, AG Bick, J Karjalainen, M Tabaka, ... Nature 586 (7831), 769-775, 2020 | 104 | 2020 |
Development of day-8 colony-forming unit-spleen hematopoietic progenitors during early murine embryogenesis: spatial and temporal mapping AL Medvinsky, OI Gan, ML Semenova, NL Samoylina | 102 | 1996 |
Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells DS Pereira, C Dorrell, CY Ito, OI Gan, B Murdoch, VN Rao, JP Zou, ... Proceedings of the National Academy of Sciences 95 (14), 8239-8244, 1998 | 101 | 1998 |