| Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ... Cell 149 (2), 307-321, 2012 | 826 | 2012 |
| Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas P Wang, Q Dong, C Zhang, PF Kuan, Y Liu, WR Jeck, JB Andersen, ... Oncogene 32 (25), 3091-3100, 2013 | 435 | 2013 |
| Inhibition of lapatinib-induced kinome reprogramming in ERBB2-positive breast cancer by targeting BET family bromodomains TJ Stuhlmiller, SM Miller, JS Zawistowski, K Nakamura, AS Beltran, ... Cell reports 11 (3), 390-404, 2015 | 334 | 2015 |
| Rho directs widespread termination of intragenic and stable RNA transcription JM Peters, RA Mooney, PF Kuan, JL Rowland, S Keleş, R Landick Proceedings of the National Academy of Sciences 106 (36), 15406-15411, 2009 | 227 | 2009 |
| Median absolute deviation to improve hit selection for genome-scale RNAi screens N Chung, XD Zhang, A Kreamer, L Locco, PF Kuan, S Bartz, PS Linsley, ... SLAS Discovery 13 (2), 149-158, 2008 | 208 | 2008 |
| Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects JM Simon, KE Hacker, D Singh, AR Brannon, JS Parker, M Weiser, TH Ho, ... Genome research 24 (2), 241-250, 2014 | 205 | 2014 |
| DiffSplice: the genome-wide detection of differential splicing events with RNA-seq Y Hu, Y Huang, Y Du, CF Orellana, D Singh, AR Johnson, A Monroy, ... Nucleic acids research 41 (2), e39-e39, 2013 | 177 | 2013 |
| HIF1α and HIF2α independently activate SRC to promote melanoma metastases SC Hanna, B Krishnan, ST Bailey, SJ Moschos, PF Kuan, T Shimamura, ... The Journal of clinical investigation 123 (5), 2078-2093, 2013 | 168 | 2013 |
| MERTK receptor tyrosine kinase is a therapeutic target in melanoma J Schlegel, MJ Sambade, S Sather, SJ Moschos, AC Tan, A Winges, ... The Journal of clinical investigation 123 (5), 2257-2267, 2013 | 150 | 2013 |
| A statistical framework for the analysis of ChIP-Seq data PF Kuan, D Chung, G Pan, JA Thomson, R Stewart, S Keleş Journal of the American Statistical Association 106 (495), 891-903, 2011 | 143 | 2011 |
| Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation BP Sampey, AJ Freemerman, J Zhang, PF Kuan, JA Galanko, ... PloS one 7 (6), e38812, 2012 | 139 | 2012 |
| methylGSA: a Bioconductor package and Shiny app for DNA methylation data length bias adjustment in gene set testing X Ren, PF Kuan Bioinformatics 35 (11), 1958-1959, 2019 | 138 | 2019 |
| A statistical framework for Illumina DNA methylation arrays PF Kuan, S Wang, X Zhou, H Chu Bioinformatics 26 (22), 2849-2855, 2010 | 124 | 2010 |
| Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR AK Smith, A Ratanatharathorn, AX Maihofer, RK Naviaux, AE Aiello, ... Nature communications 11 (1), 5965, 2020 | 111 | 2020 |
| Discovering transcription factor binding sites in highly repetitive regions of genomes with multi-read analysis of ChIP-Seq data D Chung, PF Kuan, B Li, R Sanalkumar, K Liang, EH Bresnick, C Dewey, ... PLoS computational biology 7 (7), e1002111, 2011 | 103 | 2011 |
| An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders PF Kuan, MA Waszczuk, R Kotov, CJ Marsit, G Guffanti, A Gonzalez, ... Translational psychiatry 7 (6), e1158-e1158, 2017 | 97 | 2017 |
| DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival K Conway, SN Edmiston, R May, PF Kuan, H Chu, C Bryant, CK Tse, ... Breast cancer research 16, 1-18, 2014 | 96 | 2014 |
| The role of Ect2 nuclear RhoGEF activity in ovarian cancer cell transformation LP Huff, MJ DeCristo, D Trembath, PF Kuan, M Yim, J Liu, DR Cook, ... Genes & cancer 4 (11-12), 460-475, 2013 | 94 | 2013 |
| DNA‐methylation profiling distinguishes malignant melanomas from benign nevi K Conway, SN Edmiston, ZS Khondker, PA Groben, X Zhou, H Chu, ... Pigment cell & melanoma research 24 (2), 352-360, 2011 | 91 | 2011 |
| Epigenome‐wide association of PTSD from heterogeneous cohorts with a common multi‐site analysis pipeline A Ratanatharathorn, MP Boks, AX Maihofer, AE Aiello, AB Amstadter, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174 …, 2017 | 81 | 2017 |
