| Highly efficient endogenous human gene correction using designed zinc-finger nucleases FD Urnov, JC Miller, YL Lee, CM Beausejour, JM Rock, S Augustus, ... Nature 435 (7042), 646-651, 2005 | 2173 | 2005 |
| Precise genome modification in the crop species Zea mays using zinc-finger nucleases VK Shukla, Y Doyon, JC Miller, RC DeKelver, EA Moehle, SE Worden, ... Nature 459 (7245), 437-441, 2009 | 1176 | 2009 |
| Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases EA Moehle, JM Rock, YL Lee, Y Jouvenot, RC DeKelver, PD Gregory, ... Proceedings of the National Academy of Sciences 104 (9), 3055-3060, 2007 | 500 | 2007 |
| Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform JM Rock, FF Hopkins, A Chavez, M Diallo, MR Chase, ER Gerrick, ... Nature microbiology 2 (4), 1-9, 2017 | 441 | 2017 |
| Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome RC DeKelver, VM Choi, EA Moehle, DE Paschon, D Hockemeyer, ... Genome research 20 (8), 1133-1142, 2010 | 367 | 2010 |
| Targeted transgene integration in plant cells using designed zinc finger nucleases CQ Cai, Y Doyon, WM Ainley, JC Miller, RC DeKelver, EA Moehle, ... Plant molecular biology 69, 699-709, 2009 | 282 | 2009 |
| Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis B Bosch, MA DeJesus, NC Poulton, W Zhang, CA Engelhart, A Zaveri, ... Cell 184 (17), 4579-4592. e24, 2021 | 139 | 2021 |
| Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes JM Rock, D Lim, L Stach, RW Ogrodowicz, JM Keck, MH Jones, ... Science 340 (6134), 871-875, 2013 | 121 | 2013 |
| The FEAR network JM Rock, A Amon Current Biology 19 (23), R1063-R1068, 2009 | 104 | 2009 |
| TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities AF Carey, JM Rock, IV Krieger, MR Chase, M Fernandez-Suarez, ... PLoS pathogens 14 (3), e1006939, 2018 | 86 | 2018 |
| DNA replication fidelity in Mycobacterium tuberculosis is mediated by an ancestral prokaryotic proofreader JM Rock, UF Lang, MR Chase, CB Ford, ER Gerrick, R Gawande, ... Nature genetics 47 (6), 677-681, 2015 | 80 | 2015 |
| Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response ER Gerrick, T Barbier, MR Chase, R Xu, J François, VH Lin, MJ Szucs, ... Proceedings of the National Academy of Sciences 115 (25), 6464-6469, 2018 | 76 | 2018 |
| Cdc15 integrates Tem1 GTPase-mediated spatial signals with Polo kinase-mediated temporal cues to activate mitotic exit JM Rock, A Amon Genes & development 25 (18), 1943-1954, 2011 | 75 | 2011 |
| CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis S Li, NC Poulton, JS Chang, ZA Azadian, MA DeJesus, N Ruecker, ... Nature Microbiology 7 (6), 766-779, 2022 | 71 | 2022 |
| Two accessory proteins govern MmpL3 mycolic acid transport in mycobacteria A Fay, N Czudnochowski, JM Rock, JR Johnson, NJ Krogan, ... MBio 10 (3), 10.1128/mbio. 00850-19, 2019 | 42* | 2019 |
| CRISPY-BRED and CRISPY-BRIP: efficient bacteriophage engineering KS Wetzel, CA Guerrero-Bustamante, RM Dedrick, CC Ko, KG Freeman, ... Scientific reports 11 (1), 6796, 2021 | 41 | 2021 |
| Tuberculosis drug discovery in the CRISPR era J Rock PLoS pathogens 15 (9), e1007975, 2019 | 34 | 2019 |
| The Tuberculosis Drug Accelerator at year 10: what have we learned? BB Aldridge, D Barros-Aguirre, CE Barry III, RH Bates, SJ Berthel, ... Nature medicine 27 (8), 1333-1337, 2021 | 33 | 2021 |
| CRISPR interference (CRISPRi) for targeted gene silencing in mycobacteria AI Wong, JM Rock Mycobacteria Protocols, 343-364, 2021 | 27 | 2021 |
| Effects of age on meiosis in budding yeast M Boselli, J Rock, E Ünal, SS Levine, A Amon Developmental cell 16 (6), 844-855, 2009 | 27 | 2009 |
