Richard A. Lewis
Richard A. Lewis
Novartis, Basel
Verified email at novartis.com
Title
Cited by
Cited by
Year
Lessons in molecular recognition: the effects of ligand and protein flexibility on molecular docking accuracy
JA Erickson, M Jalaie, DH Robertson, RA Lewis, M Vieth
Journal of medicinal chemistry 47 (1), 45-55, 2004
3932004
Drug design by machine learning: The use of inductive logic programming to model the structure-activity relationships of trimethoprim analogues binding to dihydrofolate reductase
RD King, S Muggleton, RA Lewis, MJ Sternberg
Proceedings of the national academy of sciences 89 (23), 11322-11326, 1992
3461992
Three-dimensional pharmacophore methods in drug discovery
AR Leach, VJ Gillet, RA Lewis, R Taylor
Journal of medicinal chemistry 53 (2), 539-558, 2010
3422010
Automated site-directed drug design using molecular lattices
RA Lewis, DC Roe, C Huang, TE Ferrin, R Langridge, ID Kuntz
Journal of molecular graphics 10 (2), 66-78, 1992
1151992
New methodology for profiling combinatorial libraries and screening sets: cleaning up the design process with HARPick
AC Good, RA Lewis
Journal of medicinal chemistry 40 (24), 3926-3936, 1997
1111997
Similarity measures for rational set selection and analysis of combinatorial libraries: the diverse property-derived (DPD) approach
RA Lewis, JS Mason, IM McLay
Journal of chemical information and computer sciences 37 (3), 599-614, 1997
1071997
Docking and scoring-theoretically easy, practically impossible?
B Coupez, RA Lewis
Current medicinal chemistry 13 (25), 2995-3003, 2006
1042006
Automated site-directed drug design: the concept of spacer skeletons for primary structure generation
RA Lewis, PM Dean
Proceedings of the Royal Society of London. B. Biological Sciences 236 (1283 …, 1989
1041989
Design and NMR-based screening of LEF, a library of chemical fragments with different local environment of fluorine
A Vulpetti, U Hommel, G Landrum, R Lewis, C Dalvit
Journal of the American Chemical Society 131 (36), 12949-12959, 2009
1022009
Comparison of conformational analysis techniques to generate pharmacophore hypotheses using catalyst
R Kristam, VJ Gillet, RA Lewis, D Thorner
Journal of chemical information and modeling 45 (2), 461-476, 2005
962005
Automated site-directed drug design: the formation of molecular templates in primary structure generation
RA Lewis, PM Dean
Proceedings of the Royal Society of London. B. Biological Sciences 236 (1283 …, 1989
861989
The graphical representation of ADME-related molecule properties for medicinal chemists
TJ Ritchie, P Ertl, R Lewis
Drug Discovery Today 16 (1-2), 65-72, 2011
762011
Current methods for site-directed structure generation
RA Lewis, AR Leach
Journal of computer-aided molecular design 8 (4), 467-475, 1994
761994
A general method for exploiting QSAR models in lead optimization
RA Lewis
Journal of medicinal chemistry 48 (5), 1638-1648, 2005
702005
Molecular diversity in drug design
PM Dean, RA Lewis
Kluwer Academic Publishers, 1999
671999
Exploiting QSAR models in lead optimization.
P Gedeck, RA Lewis
Current opinion in drug discovery & development 11 (4), 569, 2008
612008
Automated site-directed drug design: approaches to the formation of 3D molecular graphs
RA Lewis
Journal of computer-aided molecular design 4 (2), 205-210, 1990
581990
Three-dimensional quantitative structure-permeability relationship analysis for a series of inhibitors of rhinovirus replication
S Ekins, GL Durst, RE Stratford, DA Thorner, R Lewis, RJ Loncharich, ...
Journal of chemical information and computer sciences 41 (6), 1578-1586, 2001
562001
Application of machine learning to structural molecular biology
MJE Sternberg, RD King, RA Lewis, S Muggleton
Philosophical Transactions of the Royal Society of London. Series B …, 1994
551994
Computer‐Aided Molecular Diversity Analysis and Combinatorial Library Design
RA Lewis, SD Pickett, DE Clark
Reviews in Computational Chemistry, Volume 16, 1-51, 2000
522000
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