| TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging D Xu, T Jin, H Zhu, H Chen, D Ofengeim, C Zou, L Mifflin, L Pan, P Amin, ... Cell 174 (6), 1477-1491. e19, 2018 | 342 | 2018 |
| RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease D Ofengeim, S Mazzitelli, Y Ito, JP DeWitt, L Mifflin, C Zou, S Das, ... Proceedings of the National Academy of Sciences 114 (41), E8788-E8797, 2017 | 310 | 2017 |
| Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target L Mifflin, D Ofengeim, J Yuan Nature reviews Drug discovery 19 (8), 553-571, 2020 | 266 | 2020 |
| Modulating TRADD to restore cellular homeostasis and inhibit apoptosis D Xu, H Zhao, M Jin, H Zhu, B Shan, J Geng, SA Dziedzic, P Amin, ... Nature 587 (7832), 133-138, 2020 | 63 | 2020 |
| A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis L Mifflin, Z Hu, C Dufort, CC Hession, AJ Walker, K Niu, H Zhu, N Liu, ... Proceedings of the National Academy of Sciences 118 (13), e2025102118, 2021 | 48 | 2021 |
| Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses S Liu, S Punthambaker, EPR Iyer, T Ferrante, D Goodwin, D Fürth, ... Nucleic acids research 49 (10), e58-e58, 2021 | 45 | 2021 |
| RIPK1 promotes energy sensing by the mTORC1 pathway A Najafov, HS Luu, AK Mookhtiar, L Mifflin, H Xia, PP Amin, A Ordureau, ... Molecular cell 81 (2), 370-385. e7, 2021 | 32 | 2021 |
| NEK1-mediated retromer trafficking promotes blood–brain barrier integrity by regulating glucose metabolism and RIPK1 activation H Wang, W Qi, C Zou, Z Xie, M Zhang, MG Naito, L Mifflin, Z Liu, A Najafov, ... Nature communications 12 (1), 4826, 2021 | 26 | 2021 |
| Reduction of mNAT1/hNAT2 contributes to cerebral endothelial necroptosis and Aβ accumulation in Alzheimer’s disease C Zou, L Mifflin, Z Hu, T Zhang, B Shan, H Wang, X Xing, H Zhu, ... Cell reports 33 (10), 2020 | 26 | 2020 |
| Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response W Li, B Shan, C Zou, H Wang, MM Zhang, H Zhu, MG Naito, D Xu, ... Cell Research 32 (7), 621-637, 2022 | 19 | 2022 |
| CREB-mediated alterations in the amygdala transcriptome: coordinated regulation of immune response genes following cocaine LE Ecke, JN Cleck, P White, J Schug, L Mifflin, JA Blendy International Journal of Neuropsychopharmacology 14 (8), 1111-1126, 2011 | 8 | 2011 |
| Methods and compositions for inhibiting necroptosis in neurovascular and/or neurodegenerative diseases or disorders J Yuan, C Zou, L Mifflin US Patent App. 17/097,695, 2021 | 1 | 2021 |
| RIPK1-Regulated Neuroinflammation and Cell Death in Amyotrophic Lateral Sclerosis and Alzheimer’s Disease LE Mifflin Harvard University, 2021 | | 2021 |
| Discovery of a Novel Subset of Pro-Inflammatory Microglia in Amyotrophic Lateral Sclerosis L Mifflin Harvard University, 2018 | | 2018 |
