The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ... Nucleic Acids Research 48 (4), 1607-1626, 2020 | 90 | 2020 |
5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ... Journal of the American Chemical Society 140 (18), 5987-5999, 2018 | 76 | 2018 |
Applications of phosphate modification and labeling to study (m) RNA caps M Warminski, PJ Sikorski, J Kowalska, J Jemielity Phosphate Labeling and Sensing in Chemical Biology, 211-239, 2017 | 51 | 2017 |
Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies MR Baranowski, A Nowicka, AM Rydzik, M Warminski, R Kasprzyk, ... The Journal of organic chemistry 80 (8), 3982-3997, 2015 | 39 | 2015 |
Phosphodiester modifications in mRNA poly (A) tail prevent deadenylation without compromising protein expression D Strzelecka, M Smietanski, PJ Sikorski, M Warminski, J Kowalska, ... RNA 26 (12), 1815-1837, 2020 | 36 | 2020 |
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation A Galloway, A Kaskar, D Ditsova, A Atrih, H Yoshikawa, C Gomez-Moreira, ... Nucleic Acids Research 49 (12), 6722-6738, 2021 | 31 | 2021 |
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to … AM Rydzik, M Warminski, PJ Sikorski, MR Baranowski, S Walczak, ... Nucleic Acids Research 45 (15), 8661-8675, 2017 | 30 | 2017 |
2′-O-Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to … K Drazkowska, R Tomecki, M Warminski, N Baran, D Cysewski, A Depaix, ... Nucleic acids research 50 (16), 9051-9071, 2022 | 29 | 2022 |
The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation M Warminski, J Kowalska, J Buck, J Zuberek, M Lukaszewicz, C Nicola, ... Bioorganic & medicinal chemistry letters 23 (13), 3753-3758, 2013 | 26 | 2013 |
Azido‐Functionalized 5′ Cap Analogues for the Preparation of Translationally Active mRNAs Suitable for Fluorescent Labeling in Living Cells A Mamot, PJ Sikorski, M Warminski, J Kowalska, J Jemielity Angewandte Chemie 129 (49), 15834-15838, 2017 | 23 | 2017 |
Structural insights into the interaction of clinically relevant phosphorothioate mRNA cap analogs with translation initiation factor 4E reveal stabilization via electrostatic … M Warminski, J Kowalska, E Nowak, D Kubacka, R Tibble, R Kasprzyk, ... ACS Chemical Biology 16 (2), 334-343, 2021 | 20 | 2021 |
Amino-functionalized 5′ cap analogs as tools for site-specific sequence-independent labeling of mRNA M Warminski, PJ Sikorski, Z Warminska, M Lukaszewicz, A Kropiwnicka, ... Bioconjugate Chemistry 28 (7), 1978-1992, 2017 | 20 | 2017 |
5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by 19F NMR MR Baranowski, M Warminski, J Jemielity, J Kowalska Nucleic Acids Research 48 (15), 8209-8224, 2020 | 18 | 2020 |
Nicotinamide-containing di-and trinucleotides as chemical tools for studies of NAD-capped RNAs A Mlynarska-Cieslak, A Depaix, E Grudzien-Nogalska, PJ Sikorski, ... Organic letters 20 (23), 7650-7655, 2018 | 17 | 2018 |
Kinetic analysis of IFIT1 and IFIT5 interactions with different native and engineered RNAs and its consequences for designing mRNA-based therapeutics B Miedziak, A Dobieżyńska, ZM Darżynkiewicz, J Bartkowska, ... RNA 26 (1), 58-68, 2020 | 15 | 2020 |
Clickable trimethylguanosine cap analogs modified within the triphosphate bridge: synthesis, conjugation to RNA and susceptibility to degradation BA Wojtczak, M Warminski, J Kowalska, M Lukaszewicz, M Honcharenko, ... RSC advances 6 (10), 8317-8328, 2016 | 15 | 2016 |
Synthesis of RNA 5′-Azides from 2′-O-Pivaloyloxymethyl-Protected RNAs and Their Reactivity in Azide–Alkyne Cycloaddition Reactions M Warminski, J Kowalska, J Jemielity Organic letters 19 (13), 3624-3627, 2017 | 13 | 2017 |
Chemical modifications of mRNA ends for therapeutic applications M Warminski, A Mamot, A Depaix, J Kowalska, J Jemielity Accounts of Chemical Research 56 (20), 2814-2826, 2023 | 11 | 2023 |
Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis JK Peters, RW Tibble, M Warminski, J Jemielity, JD Gross Structure 30 (5), 721-732. e4, 2022 | 8 | 2022 |
Selective Chemical Modification of DNA with Boronic Acids by On-Column CuAAc Reactions M Debiais, JJ Vasseur, S Müller, M Smietana Synthesis 52 (20), 2962-2969, 2020 | 8 | 2020 |