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Scott Loughhead
Scott Loughhead
Verified email at fas.harvard.edu
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Cited by
Year
The chemokine receptor CX3CR1 defines three antigen-experienced CD8 T cell subsets with distinct roles in immune surveillance and homeostasis
C Gerlach, EA Moseman, SM Loughhead, D Alvarez, AJ Zwijnenburg, ...
Immunity 45 (6), 1270-1284, 2016
5052016
Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex
H Prüss, A Tedeschi, A Thiriot, L Lynch, SM Loughhead, S Stutte, IB Mazo, ...
Nature neuroscience 20 (11), 1549-1559, 2017
1672017
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo
T DiTommaso, JM Cole, L Cassereau, JA Buggé, JLS Hanson, ...
Proceedings of the National Academy of Sciences 115 (46), E10907-E10914, 2018
1602018
Antigen availability determines CD8+ T cell-dendritic cell interaction kinetics and memory fate decisions
SE Henrickson, M Perro, SM Loughhead, B Senman, S Stutte, M Quigley, ...
Immunity 39 (3), 496-507, 2013
1582013
Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity
D Zemmour, A Pratama, SM Loughhead, D Mathis, C Benoist
Proceedings of the National Academy of Sciences 114 (17), E3472-E3480, 2017
1442017
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice
Y Liu, NV Belkina, C Park, R Nambiar, SM Loughhead, G Patino-Lopez, ...
Blood, The Journal of the American Society of Hematology 119 (2), 445-453, 2012
1122012
Targeted delivery of immunomodulators to lymph nodes
J Azzi, Q Yin, M Uehara, S Ohori, L Tang, K Cai, T Ichimura, M McGrath, ...
Cell reports 15 (6), 1202-1213, 2016
962016
Polyfunctional CD4+ T Cell Responses to Immunodominant Epitopes Correlate with Disease Activity of Virulent Salmonella
M Maybeno, A Redeker, SPM Welten, B Peters, SM Loughhead, ...
Public Library of Science 7 (8), e43481, 2012
302012
Microfluidic squeezing enables MHC class I antigen presentation by diverse immune cells to elicit CD8+ T cell responses with antitumor activity
MG Booty, KA Hlavaty, A Stockmann, EI Ozay, C Smith, L Tian, E How, ...
The Journal of Immunology 208 (4), 929-940, 2022
132022
Intracellular delivery of biomolecules to induce tolerance
JB Gilbert, W Bu, S Loughhead, H Bernstein, AR Sharei, F Moore
US Patent App. 16/098,404, 2019
82019
Cell Squeeze: driving more effective CD8 T-cell activation through cytosolic antigen delivery
JC Park, H Bernstein, S Loughhead, R Zwirtes, J Jennings, V Nicolini, ...
Immuno-Oncology and Technology 16, 100091, 2022
62022
Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A* 02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid …
A Jimeno, JC Baranda, MM Mita, MS Gordon, MH Taylor, WT Iams, ...
Journal of Clinical Oncology 39 (15_suppl), 2536-2536, 2021
62021
Figuring fact from fiction: unbiased polling of memory T cells
C Gerlach, SM Loughhead, UH von Andrian
Cell 161 (4), 702-704, 2015
52015
Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice
K Blagovic, CK Smith, A Ramakrishnan, L Moore, DR Soto, Z Thompson, ...
Frontiers in Immunology 13, 1015585, 2022
42022
Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A* 02+ patients with HPV16+ solid tumors
A Jimeno, J Baranda, WT Iams, JC Park, M Mita, MS Gordon, M Taylor, ...
Investigational new drugs 41 (2), 284-295, 2023
32023
48MO SQZ-PBMC-HPV-101: Preliminary results of a first-in-human, dose-escalation study of a cell-based vaccine in HLA A* 02+ patients with recurrent, locally advanced, or …
JC Park, JC Baranda, MM Mita, WT Iams, MS Gordon, M Taylor, N Dhani, ...
Annals of Oncology 32, S1393, 2021
32021
Intracellular delivery of biomolecules to induce tolerance
S Loughhead, JB Gilbert, H Bernstein, AR Sharei, F Moore
US Patent App. 16/098,405, 2021
32021
Intracellular delivery of biomolecules to modify immune response
S Loughhead, L Talarico, A Vicente-Suarez, M Booty, H Bernstein, ...
US Patent App. 16/980,339, 2021
32021
Methods for treating hpv-associated diseases
S Loughhead, L Talarico, A Vicente-Suarez, M Booty, H Bernstein, ...
US Patent App. 16/980,341, 2021
32021
169 Microfluidics cell squeezing enables human PBMCs as drivers of antigen-specific CD8 T responses across broad range of antigens for diverse clinical applications
M Maloney, S Loughhead, A Ramakrishnan, C Smith, A Venkitaraman, ...
Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020
32020
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