| C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins YJ Zhang, TF Gendron, JC Grima, H Sasaguri, K Jansen-West, YF Xu, ... Nature neuroscience 19 (5), 668-677, 2016 | 321 | 2016 |
| DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ... The EMBO journal 35 (14), 1537-1549, 2016 | 207 | 2016 |
| The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease LJ Blair, JD Baker, JJ Sabbagh, CA Dickey Journal of neurochemistry 133 (1), 1-13, 2015 | 109 | 2015 |
| Hsp90 activator Aha1 drives production of pathological tau aggregates LB Shelton, JD Baker, D Zheng, LE Sullivan, PK Solanki, JM Webster, ... Proceedings of the National Academy of Sciences 114 (36), 9707-9712, 2017 | 107 | 2017 |
| Cellular factors modulating the mechanism of tau protein aggregation SN Fontaine, JJ Sabbagh, J Baker, CR Martinez-Licha, A Darling, ... Cellular and molecular life sciences 72, 1863-1879, 2015 | 86 | 2015 |
| Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex J Oroz, BJ Chang, P Wysoczanski, CT Lee, Á Pérez-Lara, P Chakraborty, ... Nature communications 9 (1), 4532, 2018 | 75 | 2018 |
| A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease JD Baker, RL Uhrich, GC Kraemer, JE Love, BC Kraemer PloS one 16 (2), e0245962, 2021 | 62 | 2021 |
| Hsp90 heterocomplexes regulate steroid hormone receptors: from stress response to psychiatric disease JD Baker, I Ozsan, S Rodriguez Ospina, D Gulick, LJ Blair International journal of molecular sciences 20 (1), 79, 2018 | 61 | 2018 |
| Human cyclophilin 40 unravels neurotoxic amyloids JD Baker, LB Shelton, D Zheng, F Favretto, BA Nordhues, A Darling, ... PLoS biology 15 (6), e2001336, 2017 | 61 | 2017 |
| Targeting the FKBP51/GR/Hsp90 complex to identify functionally relevant treatments for depression and PTSD JJ Sabbagh, RA Cordova, D Zheng, M Criado-Marrero, A Lemus, P Li, ... ACS chemical biology 13 (8), 2288-2299, 2018 | 40 | 2018 |
| Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response LA Sandusky-Beltran, A Kovalenko, C Ma, JIT Calahatian, DS Placides, ... Alzheimer's Research & Therapy 11, 1-24, 2019 | 37 | 2019 |
| Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice M Criado-Marrero, NT Gebru, DM Blazier, LA Gould, JD Baker, ... Acta neuropathologica communications 9, 1-16, 2021 | 33 | 2021 |
| Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology LA Sandusky-Beltran, A Kovalenko, DS Placides, K Ratnasamy, C Ma, ... The Journal of Clinical Investigation 131 (4), 2021 | 27 | 2021 |
| The Molecular Basis of the Interaction of Cyclophilin A with α‐Synuclein F Favretto, JD Baker, T Strohäker, LB Andreas, LJ Blair, S Becker, ... Angewandte Chemie International Edition 59 (14), 5643-5646, 2020 | 23 | 2020 |
| Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war F Favretto, D Flores, JD Baker, T Strohäker, LB Andreas, LJ Blair, ... Nature Communications 11 (1), 6046, 2020 | 21 | 2020 |
| Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins AL Darling, L Breydo, EG Rivas, NT Gebru, D Zheng, JD Baker, LJ Blair, ... International journal of biological macromolecules 127, 136-145, 2019 | 19 | 2019 |
| Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules MD Martin, JD Baker, A Suntharalingam, BA Nordhues, LB Shelton, ... ACS chemical biology 11 (7), 2041-2048, 2016 | 18 | 2016 |
| Targeting pathological tau by small molecule inhibition of the poly (A): MSUT2 RNA–protein interaction JD Baker, RL Uhrich, TJ Strovas, AD Saxton, BC Kraemer ACS chemical neuroscience 11 (15), 2277-2285, 2020 | 17 | 2020 |
| Tau–RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change PJ McMillan, SJ Benbow, R Uhrich, A Saxton, M Baum, T Strovas, ... Brain 146 (8), 3206-3220, 2023 | 9 | 2023 |
| AlphaScreen identifies MSUT2 inhibitors for tauopathy-targeting therapeutic discovery JD Baker, RL Uhrich, TJ Strovas, AD Saxton, BC Kraemer SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (3), 400-409, 2021 | 2 | 2021 |
Laura BlairUniversity of South FloridaVerified email at usf.edu
