G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation C Sina, O Gavrilova, M Förster, A Till, S Derer, F Hildebrand, B Raabe, ... The Journal of Immunology 183 (11), 7514-7522, 2009 | 442 | 2009 |
Human IgG2 antibodies against epidermal growth factor receptor effectively trigger antibody-dependent cellular cytotoxicity but, in contrast to IgG1, only by cells of myeloid … T Schneider-Merck, JJ Lammerts van Bueren, S Berger, K Rossen, ... The journal of immunology 184 (1), 512-520, 2010 | 270 | 2010 |
The intestinal complement system in inflammatory bowel disease: Shaping intestinal barrier function C Sina, C Kemper, S Derer Seminars in immunology 37, 66-73, 2018 | 131 | 2018 |
Boosting ADCC and CDC activity by Fc engineering and evaluation of antibody effector functions C Kellner, S Derer, T Valerius, M Peipp Methods 65 (1), 105-113, 2014 | 90 | 2014 |
Recombinant dimeric IgA antibodies against the epidermal growth factor receptor mediate effective tumor cell killing S Lohse, S Derer, T Beyer, K Klausz, M Peipp, JHW Leusen, ... The Journal of Immunology 186 (6), 3770-3778, 2011 | 90 | 2011 |
Impact of epidermal growth factor receptor (EGFR) cell surface expression levels on effector mechanisms of EGFR antibodies S Derer, P Bauer, S Lohse, AH Scheel, S Berger, C Kellner, M Peipp, ... The Journal of Immunology 189 (11), 5230-5239, 2012 | 89 | 2012 |
Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis ST Jendrek, D Gotthardt, T Nitzsche, L Widmann, T Korf, MA Michaels, ... Gut 66 (1), 137-144, 2017 | 86 | 2017 |
Circadian rhythm disruption impairs tissue homeostasis and exacerbates chronic inflammation in the intestine R Pagel, F Bär, T Schröder, A Sünderhauf, A Künstner, SM Ibrahim, ... The FASEB Journal 31 (11), 4707, 2017 | 82 | 2017 |
An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo S Lohse, S Meyer, LAPM Meulenbroek, JHM Jansen, M Nederend, ... Cancer research 76 (2), 403-417, 2016 | 73 | 2016 |
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis T Schröder, D Kucharczyk, F Bär, R Pagel, S Derer, ST Jendrek, ... Molecular metabolism 5 (4), 283-295, 2016 | 68 | 2016 |
Regulation of epithelial cell expressed C3 in the intestine–Relevance for the pathophysiology of inflammatory bowel disease? A Sünderhauf, K Skibbe, S Preisker, K Ebbert, A Verschoor, CM Karsten, ... Molecular immunology 90, 227-238, 2017 | 64 | 2017 |
Fc‐engineered EGF‐R antibodies mediate improved antibody‐dependent cellular cytotoxicity (ADCC) against KRAS‐mutated tumor cells M Schlaeth, S Berger, S Derer, K Klausz, S Lohse, M Dechant, GA Lazar, ... Cancer science 101 (5), 1080-1088, 2010 | 60 | 2010 |
Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity S Derer, P Glorius, M Schlaeth, S Lohse, K Klausz, U Muchhal, ... MAbs 6 (2), 409-421, 2014 | 59 | 2014 |
Pancreatic autoantibodies against CUZD1 and GP2 are associated with distinct clinical phenotypes of Crohn's disease MA Michaels, ST Jendrek, T Korf, T Nitzsche, B Teegen, L Komorowski, ... Inflammatory bowel diseases 21 (12), 2864-2872, 2015 | 51 | 2015 |
Characterization of a mutated IgA2 antibody of the m (1) allotype against the epidermal growth factor receptor for the recruitment of monocytes and macrophages S Lohse, C Brunke, S Derer, M Peipp, P Boross, C Kellner, T Beyer, ... Journal of Biological Chemistry 287 (30), 25139-25150, 2012 | 51 | 2012 |
Enhancing natural killer cell-mediated lysis of lymphoma cells by combining therapeutic antibodies with CD20-specific immunoligands engaging NKG2D or NKp30 C Kellner, A Günther, A Humpe, R Repp, K Klausz, S Derer, T Valerius, ... Oncoimmunology 5 (1), e1058459, 2016 | 47 | 2016 |
HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity M Peipp, S Derer, S Lohse, M Staudinger, K Klausz, T Valerius, ... Oncotarget 6 (31), 32075, 2015 | 47 | 2015 |
Complement in antibody-based tumor therapy S Derer, FJ Beurskens, T Rosner, M Peipp, T Valerius Critical Reviews™ in Immunology 34 (3), 2014 | 45 | 2014 |
Dietary ursolic acid improves health span and life span in male Drosophila melanogaster S Staats, AE Wagner, K Lüersen, A Künstner, T Meyer, AK Kahns, S Derer, ... Biofactors 45 (2), 169-186, 2019 | 44 | 2019 |
Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity (ADCC), and complement dependent … S Lohse, S Loew, A Kretschmer, JH Jansen, S Meyer, T Ten Broeke, ... British Journal of Haematology 181 (3), 413-417, 2018 | 43 | 2018 |