| TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis J Sreedharan, IP Blair, VB Tripathi, X Hu, C Vance, B Rogelj, S Ackerley, ... Science 319 (5870), 1668-1672, 2008 | 2975 | 2008 |
| Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ... Science 323 (5918), 1208-1211, 2009 | 2965 | 2009 |
| The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings RW Paterson, RL Brown, L Benjamin, R Nortley, S Wiethoff, T Bharucha, ... Brain 143 (10), 3104-3120, 2020 | 1208 | 2020 |
| Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis NJ Rutherford, YJ Zhang, M Baker, JM Gass, NCA Finch, YF Xu, ... PLoS genetics 4 (9), e1000193, 2008 | 529 | 2008 |
| Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13. 2–21.3 C Vance, A Al-Chalabi, D Ruddy, BN Smith, X Hu, J Sreedharan, ... Brain 129 (4), 868-876, 2006 | 495 | 2006 |
| Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age-and dose-dependent fashion JC Mitchell, P McGoldrick, C Vance, T Hortobagyi, J Sreedharan, B Rogelj, ... Acta neuropathologica 125, 273-288, 2013 | 313 | 2013 |
| Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS TM Miller, ME Cudkowicz, A Genge, PJ Shaw, G Sobue, RC Bucelli, ... New England Journal of Medicine 387 (12), 1099-1110, 2022 | 282 | 2022 |
| TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD MA White, E Kim, A Duffy, R Adalbert, BU Phillips, OM Peters, ... Nature neuroscience 21 (4), 552-563, 2018 | 226 | 2018 |
| Amyotrophic lateral sclerosis: problems and prospects J Sreedharan, RH Brown Jr Annals of neurology 74 (3), 309-316, 2013 | 176 | 2013 |
| Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS K Weskamp, EM Tank, R Miguez, JP McBride, NB Gómez, M White, Z Lin, ... The Journal of clinical investigation 130 (3), 1139-1155, 2020 | 94 | 2020 |
| Age-dependent TDP-43-mediated motor neuron degeneration requires GSK3, hat-trick, and xmas-2 J Sreedharan, LJ Neukomm, RH Brown, MR Freeman Current Biology 25 (16), 2130-2136, 2015 | 85 | 2015 |
| Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss MA White, Z Lin, E Kim, CM Henstridge, E Pena Altamira, CK Hunt, ... Acta neuropathologica communications 7, 1-16, 2019 | 68 | 2019 |
| Amyotrophic lateral sclerosis: recent genetic highlights MA White, J Sreedharan Current opinion in neurology 29 (5), 557-564, 2016 | 42 | 2016 |
| Relative preservation of triceps over biceps strength in upper limb-onset ALS: The ‘split elbow’ R Khalaf, S Martin, C Ellis, R Burman, J Sreedharan, C Shaw, PN Leigh, ... Journal of Neurology, Neurosurgery & Psychiatry 90 (7), 730-733, 2019 | 39 | 2019 |
| Predicting the future of ALS: the impact of demographic change and potential new treatments on the prevalence of ALS in the United Kingdom, 2020–2116 A Gowland, S Opie-Martin, KM Scott, AR Jones, PR Mehta, CJ Batts, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (3-4), 264-274, 2019 | 32 | 2019 |
| Optimizing reproducibility of operant testing through reinforcer standardization: identification of key nutritional constituents determining reward strength in touchscreens EW Kim, BU Phillips, CJ Heath, SY Cho, H Kim, J Sreedharan, HT Song, ... Molecular brain 10, 1-10, 2017 | 29 | 2017 |
| Alexander disease with hypothermia, microcoria, and psychiatric and endocrine disturbances J Sreedharan, CE Shaw, J Jarosz, M Samuel Neurology 68 (16), 1322-1323, 2007 | 27 | 2007 |
| Falsely pessimistic prognosis by EEG in post-anoxic coma after cardiac arrest: the borderland of nonconvulsive status epilepticus J Sreedharan, E Gourlay, MR Evans, M Koutroumanidis Epileptic Disorders 14, 340-344, 2012 | 17 | 2012 |
| Striking phenotypic variation in a family with the P506S UBQLN2 mutation including amyotrophic lateral sclerosis, spastic paraplegia, and frontotemporal dementia SA Gkazi, C Troakes, S Topp, JW Miller, CA Vance, J Sreedharan, ... Neurobiology of Aging 73, 229. e5-229. e9, 2019 | 16 | 2019 |
| Female sex mitigates motor and behavioural phenotypes in TDP-43Q331K knock-in mice J Watkins, A Ghosh, AFA Keerie, JJP Alix, RJ Mead, J Sreedharan Scientific Reports 10 (1), 19220, 2020 | 15 | 2020 |
Christopher E ShawInstitute of Psychiatry, King's College LondonVerifierad e-postadress på kcl.ac.uk
