Urea cycle dysregulation in non-alcoholic fatty liver disease F De Chiara, S Heebøll, G Marrone, C Montoliu, S Hamilton-Dutoit, ... Journal of hepatology 69 (4), 905-915, 2018 | 157 | 2018 |
Ammonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension R Jalan, F De Chiara, V Balasubramaniyan, F Andreola, V Khetan, ... Journal of hepatology 64 (4), 823-833, 2016 | 129 | 2016 |
Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α MA Ortega, X Fernández-Garibay, AG Castaño, F De Chiara, ... Lab on a Chip 19 (15), 2568-2580, 2019 | 111 | 2019 |
Immunomodulatory and antioxidant function of albumin stabilises the endothelium and improves survival in a rodent model of chronic liver failure R Garcia-Martinez, F Andreola, G Mehta, K Poulton, M Oria, M Jover, ... Journal of hepatology 62 (4), 799-806, 2015 | 89 | 2015 |
Ammonia scavenging prevents progression of fibrosis in experimental nonalcoholic fatty liver disease F De Chiara, KL Thomsen, A Habtesion, H Jones, N Davies, ... Hepatology 71 (3), 874-892, 2020 | 78 | 2020 |
Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis KL Thomsen, F De Chiara, K Rombouts, H Vilstrup, F Andreola, ... Medical hypotheses 113, 91-97, 2018 | 43 | 2018 |
New perspectives for natural antimicrobial peptides: application as antinflammatory drugs in a murine model R Capparelli, F De Chiara, N Nocerino, RC Montella, M Iannaccone, ... BMC immunology 13, 1-14, 2012 | 38 | 2012 |
Recombinant alkaline phosphatase prevents acute on chronic liver failure C Engelmann, D Adebayo, M Oria, F De Chiara, S Novelli, A Habtesion, ... Scientific Reports 10 (1), 389, 2020 | 36 | 2020 |
Ammonia mediates cortical hemichannel dysfunction in rodent models of chronic liver disease A Hadjihambi, F De Chiara, PS Hosford, A Habtetion, A Karagiannis, ... Hepatology 65 (4), 1306-1318, 2017 | 33 | 2017 |
High protein diet and metabolic plasticity in non-alcoholic fatty liver disease: myths and truths F De Chiara, C Ureta Checcllo, J Ramon Azcon Nutrients 11 (12), 2985, 2019 | 32 | 2019 |
The MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis R Capparelli, F De Chiara, A Di Matteo, C Medaglia, D Iannelli Genes & Immunity 14 (8), 504-511, 2013 | 31 | 2013 |
Exogenous liposomal ceramide-C6 ameliorates lipidomic profile, energy homeostasis, and anti-oxidant systems in NASH F Zanieri, A Levi, D Montefusco, L Longato, F De Chiara, L Frenguelli, ... Cells 9 (5), 1237, 2020 | 14 | 2020 |
Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies R Jalan, RP Mookerjee, K Rombouts, F Andreola, F De Chiara, ... US Patent 10,039,735, 2018 | 14 | 2018 |
The adenosine monophosphate–activated protein kinase—Vacuolar adenosine triphosphatase–pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells G Marrone, F De Chiara, K Böttcher, A Levi, D Dhar, L Longato, G Mazza, ... Hepatology 68 (3), 1140-1153, 2018 | 13 | 2018 |
Early increase in ammonia is a feature of non-alcoholic fatty liver disease and the ammonia lowering drug, ornithine phenylacetate (OCR002) prevents progression of fibrosis in … F De Chiara, A Habtension, N Davies, F Andreola, K Rombouts, N Arias, ... Journal of Clinical and Experimental Hepatology 7, S73-S74, 2017 | 10 | 2017 |
Role of ammonia in NAFLD: an unusual suspect KL Thomsen, PL Eriksen, AJC Kerbert, F De Chiara, R Jalan, H Vilstrup JHEP Reports, 100780, 2023 | 9 | 2023 |
Collagen-Tannic Acid Spheroids for β-Cell Encapsulation Fabricated Using a 3D Bioprinter CF Laura, DC Francesco, RC Júlia, C Jordi, M Elena, G Amelie Luise, ... Advanced Material Technologies 7, 2101696, 2022 | 9 | 2022 |
The synergy between organ-on-a-chip and artificial intelligence for the study of NAFLD: from basic science to clinical research F De Chiara, A Ferret-Miñana, J Ramón-Azcón Biomedicines 9 (3), 248, 2021 | 9 | 2021 |
Ornithine transcarbamylase gene expression and hepatic urea nitrogen handling are reduced in models of NAFLD and recovers with dietary modulation and reducing bacterial … KL Thomsen, F De Chiara, F Andreola, K Rombouts, J MacNaughtan, ... HEPATOLOGY 62, 657A-657A, 2015 | 9 | 2015 |
Organs‐on‐Chips: Trends and Challenges in Advanced Systems Integration S Mughal, GA López‐Muñoz, JM Fernández‐Costa, A Cortés‐Reséndiz, ... Advanced Materials Interfaces 9 (33), 2201618, 2022 | 8 | 2022 |