| Epigenetic differences arise during the lifetime of monozygotic twins MF Fraga, E Ballestar, MF Paz, S Ropero, F Setien, ML Ballestar, ... Proceedings of the National Academy of Sciences 102 (30), 10604-10609, 2005 | 3246 | 2005 |
| Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer MF Fraga, E Ballestar, A Villar-Garea, M Boix-Chornet, J Espada, ... Nature genetics 37 (4), 391, 2005 | 1727 | 2005 |
| Genetic unmasking of an epigenetically silenced microRNA in human cancer cells A Lujambio, S Ropero, E Ballestar, MF Fraga, C Cerrato, F Setién, ... Cancer research 67 (4), 1424-1429, 2007 | 926 | 2007 |
| Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation PA Wade, A Gegonne, PL Jones, E Ballestar, F Aubry, AP Wolffe Nature genetics 23 (1), 62, 1999 | 924 | 1999 |
| Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex H Peinado, E Ballestar, M Esteller, A Cano Molecular and cellular biology 24 (1), 306-319, 2004 | 675 | 2004 |
| Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus BM Javierre, AF Fernandez, J Richter, F Al-Shahrour, JI Martin-Subero, ... Genome research 20 (2), 170-179, 2010 | 520 | 2010 |
| Methyl‐CpG‐binding proteins: Targeting specific gene repression E Ballestar, AP Wolffe European Journal of Biochemistry 268 (1), 1-6, 2001 | 429 | 2001 |
| Geriatric muscle stem cells switch reversible quiescence into senescence P Sousa-Victor, S Gutarra, L García-Prat, J Rodriguez-Ubreva, L Ortet, ... Nature 506 (7488), 316, 2014 | 415 | 2014 |
| Autophagy maintains stemness by preventing senescence L García-Prat, M Martínez-Vicente, E Perdiguero, L Ortet, ... Nature 529 (7584), 37, 2016 | 376 | 2016 |
| Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer O Aguilera, MF Fraga, E Ballestar, MF Paz, M Herranz, J Espada, ... Oncogene 25 (29), 4116, 2006 | 374 | 2006 |
| Methyl‐CpG binding proteins identify novel sites of epigenetic inactivation in human cancer E Ballestar, MF Paz, L Valle, S Wei, MF Fraga, J Espada, JC Cigudosa, ... The EMBO journal 22 (23), 6335-6345, 2003 | 374 | 2003 |
| Notch signaling is essential for ventricular chamber development J Grego-Bessa, L Luna-Zurita, G del Monte, V Bolós, P Melgar, ... Developmental cell 12 (3), 415-429, 2007 | 352 | 2007 |
| DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E G Lund, L Andersson, M Lauria, M Lindholm, MF Fraga, A Villar-Garea, ... Journal of Biological Chemistry 279 (28), 29147-29154, 2004 | 316 | 2004 |
| A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition S Ropero, MF Fraga, E Ballestar, R Hamelin, H Yamamoto, ... Nature genetics 38 (5), 566, 2006 | 259 | 2006 |
| Allele‐specific histone lysine methylation marks regulatory regions at imprinted mouse genes C Fournier, Y Goto, E Ballestar, K Delaval, AM Hever, M Esteller, R Feil The EMBO journal 21 (23), 6560-6570, 2002 | 256 | 2002 |
| A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors MF Fraga, M Herranz, J Espada, E Ballestar, MF Paz, S Ropero, E Erkek, ... Cancer research 64 (16), 5527-5534, 2004 | 252 | 2004 |
| A DNA methylation fingerprint of 1628 human samples AF Fernandez, Y Assenov, JI Martin-Subero, B Balint, R Siebert, ... Genome research 22 (2), 407-419, 2012 | 250 | 2012 |
| The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer AF Fernandez, C Rosales, P Lopez-Nieva, O Graña, E Ballestar, ... Genome research 19 (3), 438-451, 2009 | 247 | 2009 |
| The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties MF Fraga, E Ballestar, G Montoya, P Taysavang, PA Wade, M Esteller Nucleic acids research 31 (6), 1765-1774, 2003 | 245 | 2003 |
| Data integration in the era of omics: current and future challenges D Gomez-Cabrero, I Abugessaisa, D Maier, A Teschendorff, ... BMC systems biology 8 (2), I1, 2014 | 242 | 2014 |