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Changhan David Lee
Changhan David Lee
Verifierad e-postadress på usc.edu
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Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ...
Science translational medicine 4 (124), 124ra27-124ra27, 2012
8002012
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
L Raffaghello, C Lee, FM Safdie, M Wei, F Madia, G Bianchi, VD Longo
Proceedings of the National Academy of Sciences 105 (24), 8215-8220, 2008
6552008
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
C Lee, J Zeng, BG Drew, T Sallam, A Martin-Montalvo, J Wan, SJ Kim, ...
Cell metabolism 21 (3), 443-454, 2015
5872015
Fasting and cancer treatment in humans: A case series report
FM Safdie, T Dorff, D Quinn, L Fontana, M Wei, C Lee, P Cohen, ...
Aging (Albany NY) 1 (12), 988, 2009
4962009
Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients
C Lee, VD Longo
Oncogene 30 (30), 3305-3316, 2011
4162011
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
C Lee, FM Safdie, L Raffaghello, M Wei, F Madia, E Parrella, D Hwang, ...
Cancer research 70 (4), 1564-1572, 2010
3562010
Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity
S Di Biase, C Lee, S Brandhorst, B Manes, R Buono, CW Cheng, ...
Cancer cell 30 (1), 136-146, 2016
3502016
Humanin: a harbinger of mitochondrial-derived peptides?
C Lee, K Yen, P Cohen
Trends in Endocrinology & Metabolism 24 (5), 222-228, 2013
2922013
Fasting enhances the response of glioma to chemo-and radiotherapy
F Safdie, S Brandhorst, M Wei, W Wang, C Lee, S Hwang, PS Conti, ...
Public Library of Science 7 (9), e44603, 2012
2522012
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers
LJ Cobb, C Lee, J Xiao, K Yen, RG Wong, HK Nakamura, HH Mehta, ...
Aging (Albany NY) 8 (4), 796, 2016
2352016
Dietary restriction with and without caloric restriction for healthy aging
C Lee, V Longo
F1000Research 5, 2016
2232016
The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress
KH Kim, JM Son, BA Benayoun, C Lee
Cell metabolism 28 (3), 516-524. e7, 2018
2182018
The emerging role of the mitochondrial-derived peptide humanin in stress resistance
K Yen, C Lee, H Mehta, P Cohen
J Mol Endocrinol 50 (1), R11-R19, 2013
2172013
MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism
C Lee, KH Kim, P Cohen
Free Radical Biology and Medicine 100, 182-187, 2016
1582016
Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
IY Choi, C Lee, VD Longo
Molecular and cellular endocrinology 455, 4-12, 2017
1482017
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
JC Reynolds, RW Lai, JST Woodhead, JH Joly, CJ Mitchell, ...
Nature communications 12 (1), 470, 2021
1132021
Mitochondrial-derived peptides in energy metabolism
TL Merry, A Chan, JST Woodhead, JC Reynolds, H Kumagai, SJ Kim, ...
American Journal of Physiology-Endocrinology and Metabolism 319 (4), E659-E666, 2020
842020
IGF‐I regulates the age‐dependent signaling peptide humanin
C Lee, J Wan, B Miyazaki, Y Fang, J Guevara‐Aguirre, K Yen, V Longo, ...
Aging Cell 13 (5), 958-961, 2014
832014
Starvation, detoxification, and multidrug resistance in cancer therapy
C Lee, L Raffaghello, VD Longo
Drug Resistance Updates 15 (1-2), 114-122, 2012
832012
Mitochondria: multifaceted regulators of aging
JM Son, C Lee
BMB reports 52 (1), 13, 2019
712019
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Artiklar 1–20