Följ
Leyuan Ma
Leyuan Ma
University of Pennsylvania/Children's Hospital of Philadelphia
Verifierad e-postadress på pennmedicine.upenn.edu - Startsida
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Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor
L Ma, T Dichwalkar, JYH Chang, B Cossette, D Garafola, AQ Zhang, ...
Science 365 (6449), 162-168, 2019
3162019
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy
N Momin, NK Mehta, NR Bennett, L Ma, JR Palmeri, MM Chinn, EA Lutz, ...
Science translational medicine 11 (498), eaaw2614, 2019
1682019
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription
Z Sheng, L Ma, JE Sun, LJ Zhu, MR Green
Blood, The Journal of the American Society of Hematology 118 (10), 2840-2848, 2011
1442011
A therapeutically targetable mechanism of BCR-ABL–independent imatinib resistance in chronic myeloid leukemia
L Ma, Y Shan, R Bai, L Xue, CA Eide, J Ou, LJ Zhu, L Hutchinson, J Cerny, ...
Science translational medicine 6 (252), 252ra121-252ra121, 2014
1382014
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
EL Dane, A Belessiotis-Richards, C Backlund, J Wang, K Hidaka, ...
Nature Materials 21 (6), 710-720, 2022
1172022
Homologous recombination as an evolutionary force in the avian influenza A virus
CQ He, ZX Xie, GZ Han, JB Dong, D Wang, JB Liu, LY Ma, XF Tang, ...
Molecular biology and evolution 26 (1), 177-187, 2009
952009
Identification of a natural multi-recombinant of Newcastle disease virus
GZ Han, CQ He, NZ Ding, LY Ma
Virology 371 (1), 54-60, 2008
752008
Resistance to vemurafenib resulting from a novel mutation in the BRAFV 600 E kinase domain
TR Wagenaar, L Ma, B Roscoe, SM Park, DN Bolon, MR Green
Pigment cell & melanoma research 27 (1), 124-133, 2014
702014
Homologous recombination is apparent in infectious bursal disease virus
CQ He, LY Ma, D Wang, GR Li, NZ Ding
Virology 384 (1), 51-58, 2009
622009
CRISPR-Cas9–mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy
L Ma, JI Boucher, J Paulsen, S Matuszewski, CA Eide, J Ou, G Eickelberg, ...
Proceedings of the national academy of sciences 114 (44), 11751-11756, 2017
552017
A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells
CS Park, AH Lewis, TJ Chen, CS Bridges, Y Shen, K Suppipat, M Puppi, ...
Blood, The Journal of the American Society of Hematology 134 (22), 1960-1972, 2019
412019
GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2
ZF Yang, H Zhang, L Ma, C Peng, Y Chen, J Wang, MR Green, S Li, ...
Proceedings of the National Academy of Sciences 110 (6), 2312-2317, 2013
332013
Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
L Ma, A Hostetler, DM Morgan, L Maiorino, I Sulkaj, CA Whittaker, ...
Cell 186 (15), 3148-3165. e20, 2023
202023
Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells
L Ma, ML Pak, J Ou, J Yu, P St. Louis, Y Shan, L Hutchinson, S Li, ...
Proceedings of the National Academy of Sciences 116 (21), 10482-10487, 2019
112019
Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses
LJ Dooling, JC Andrechak, BH Hayes, S Kadu, W Zhang, R Pan, ...
Nature Biomedical Engineering 7 (9), 1081-1096, 2023
62023
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK. CAR-T cells
E Bergaggio, WT Tai, A Aroldi, C Mecca, E Landoni, M Nüesch, I Mota, ...
Cancer cell 41 (12), 2100-2116. e10, 2023
52023
Eradication of tumors with pre-existing antigenic heterogeneity by vaccine-mediated co-engagement of CAR T and endogenous T-cells
L Ma, DM Morgan, I Sulkaj, P Yousefpour, CA Whittaker, W Abraham, N Li, ...
bioRxiv, 2022.10. 05.511036, 2022
52022
Cooperative phagocytosis underlies macrophage immunotherapy of solid tumours and initiates a broad anti-tumour IgG response
JC Andrechak, LJ Dooling, BH Hayes, S Kadu, W Zhang, R Pan, ...
biorxiv, 2022.01. 01.474150, 2022
42022
High-throughput screening of tyrosine kinase inhibitor resistant genes in CML
L Ma, J Roderick, MA Kelliher, MR Green
Chronic Myeloid Leukemia: Methods and Protocols, 159-173, 2016
42016
Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
DJ Irvine, L Ma
US Patent App. 17/257,671, 2022
22022
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Artiklar 1–20