Leyuan Ma
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BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription
Z Sheng, L Ma, JE Sun, LJ Zhu, MR Green
Blood, The Journal of the American Society of Hematology 118 (10), 2840-2848, 2011
1162011
A therapeutically targetable mechanism of BCR-ABL–independent imatinib resistance in chronic myeloid leukemia
L Ma, Y Shan, R Bai, L Xue, CA Eide, J Ou, LJ Zhu, L Hutchinson, J Cerny, ...
Science translational medicine 6 (252), 252ra121-252ra121, 2014
992014
Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor
L Ma, T Dichwalkar, JYH Chang, B Cossette, D Garafola, AQ Zhang, ...
Science 365 (6449), 162-168, 2019
892019
Homologous recombination as an evolutionary force in the avian influenza A virus
CQ He, ZX Xie, GZ Han, JB Dong, D Wang, JB Liu, LY Ma, XF Tang, ...
Molecular biology and evolution 26 (1), 177-187, 2009
852009
Identification of a natural multi-recombinant of Newcastle disease virus
GZ Han, CQ He, NZ Ding, LY Ma
Virology 371 (1), 54-60, 2008
672008
Homologous recombination is apparent in infectious bursal disease virus
CQ He, LY Ma, D Wang, GR Li, NZ Ding
Virology 384 (1), 51-58, 2009
492009
Resistance to vemurafenib resulting from a novel mutation in the BRAFV 600 E kinase domain
TR Wagenaar, L Ma, B Roscoe, SM Park, DN Bolon, MR Green
Pigment cell & melanoma research 27 (1), 124-133, 2014
462014
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy
N Momin, NK Mehta, NR Bennett, L Ma, JR Palmeri, MM Chinn, EA Lutz, ...
Science translational medicine 11 (498), 2019
362019
GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2
ZF Yang, H Zhang, L Ma, C Peng, Y Chen, J Wang, MR Green, S Li, ...
Proceedings of the National Academy of Sciences 110 (6), 2312-2317, 2013
252013
CRISPR-Cas9–mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy
L Ma, JI Boucher, J Paulsen, S Matuszewski, CA Eide, J Ou, G Eickelberg, ...
Proceedings of the national academy of sciences 114 (44), 11751-11756, 2017
232017
A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells
CS Park, AH Lewis, TJ Chen, CS Bridges, Y Shen, K Suppipat, M Puppi, ...
Blood, The Journal of the American Society of Hematology 134 (22), 1960-1972, 2019
142019
High-throughput screening of tyrosine kinase inhibitor resistant genes in CML
L Ma, J Roderick, MA Kelliher, MR Green
Chronic Myeloid Leukemia, 159-173, 2016
52016
Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells
L Ma, ML Pak, J Ou, J Yu, PS Louis, Y Shan, L Hutchinson, S Li, ...
Proceedings of the National Academy of Sciences 116 (21), 10482-10487, 2019
22019
PKC pathways mediate BCR-ABL-independent imatinib resistance in chronic myeloid leukemia
L Ma, Y Shan, R Bai, L Xue, CA Eide, J Ou, LJ Zhu, L Hutchinson, J Cerny, ...
Blood, The Journal of the American Society of Hematology 124 (21), 1790-1790, 2014
22014
KLF4 promotes self-renewal by repressing DYRK2-mediated degradation of c-Myc in leukemic stem cells: development of targeted therapy
CS Park, Y Shen, K Suppipat, J Tomolonis, M Puppi, TA Mistretta, L Ma, ...
Cancer research 76 (14 Supplement), 3334-3334, 2016
12016
Compositions for chimeric antigen receptor t cell therapy and uses thereof
DJ Irvine, L Ma
US Patent App. 16/644,893, 2020
2020
Immunotherapy
C Wang, M Silva, L Ma
Bioengineering Innovative Solutions for Cancer, 221-244, 2020
2020
Treating chronic myelogenous leukemia (CML)
MR Green, L Ma
US Patent 10,428,387, 2019
2019
KLF4 Represses DYRK2 Inhibition of Self-renewal and Survival Through c-Myc and p53 in Leukemia Stem/Progenitor Cells
CS Park, AH Lewis, TJ Chen, CS Bridges, Y Shen, K Suppipat, M Puppi, ...
Blood, 2019
2019
Pharmacologic inhibition of SIAH2 stabilizes DYRK2 and inhibits survival and self-renewal in chronic myeloid leukemia (CML) leukemic stem cells
CS Park, Y Shen, A Lewis, K Suppipat, M Puppi, J Tomolonis, T Chen, ...
Cancer Research 78 (13 Supplement), 145-145, 2018
2018
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Artiklar 1–20