The essential medicinal chemistry of curcumin: miniperspective KM Nelson, JL Dahlin, J Bisson, J Graham, GF Pauli, MA Walters Journal of medicinal chemistry 60 (5), 1620-1637, 2017 | 1770 | 2017 |
The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature chemical biology 11 (8), 536-541, 2015 | 834 | 2015 |
PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS JL Dahlin, JWM Nissink, JM Strasser, S Francis, LA Higgins, H Zhou, ... Journal of medicinal chemistry 58 (5), 2091-2113, 2015 | 357 | 2015 |
Mitigating risk in academic preclinical drug discovery JL Dahlin, J Inglese, MA Walters Nature reviews Drug discovery 14 (4), 279-294, 2015 | 177 | 2015 |
The essential roles of chemistry in high-throughput screening triage JL Dahlin, MA Walters Future medicinal chemistry 6 (11), 1265-1290, 2014 | 156 | 2014 |
The essential medicinal chemistry of cannabidiol (CBD) KM Nelson, J Bisson, G Singh, JG Graham, SN Chen, JB Friesen, ... Journal of medicinal chemistry 63 (21), 12137-12155, 2020 | 106 | 2020 |
Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors JL Dahlin, KM Nelson, JM Strasser, D Barsyte-Lovejoy, MM Szewczyk, ... Nature communications 8 (1), 1-14, 2017 | 103 | 2017 |
How to triage PAINS-full research JL Dahlin, MA Walters Assay and drug development technologies 14 (3), 168-174, 2016 | 79 | 2016 |
Assay guidance manual [Internet] S Markossian, A Grossman, K Brimacombe, M Arkin, D Auld, C Austin, ... Eli Lilly & Company and the National Center for Advancing Translational Sciences, 2004 | 65 | 2004 |
GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity D Menon, A Innes, AJ Oakley, JE Dahlstrom, LM Jensen, A Brüstle, ... Scientific reports 7 (1), 17832, 2017 | 51 | 2017 |
Assay interference by chemical reactivity JL Dahlin, J Baell, MA Walters | 47 | 2015 |
Nuisance compounds in cellular assays JL Dahlin, DS Auld, I Rothenaigner, S Haney, JZ Sexton, JWM Nissink, ... Cell chemical biology 28 (3), 356-370, 2021 | 44 | 2021 |
Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery NP Coussens, GS Sittampalam, R Guha, K Brimacombe, A Grossman, ... Clinical and translational science 11 (5), 461-470, 2018 | 44 | 2018 |
Assay interference by aggregation DS Auld, J Inglese, JL Dahlin | 43 | 2017 |
Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases JL Dahlin, X Chen, MA Walters, Z Zhang Critical reviews in biochemistry and molecular biology 50 (1), 31-53, 2015 | 43 | 2015 |
Curcumin may (not) defy science KM Nelson, JL Dahlin, J Bisson, J Graham, GF Pauli, MA Walters ACS medicinal chemistry letters 8 (5), 467-470, 2017 | 42 | 2017 |
Microplate selection and recommended practices in high-throughput screening and quantitative biology DS Auld, PA Coassin, NP Coussens, P Hensley, C Klumpp-Thomas, ... Assay Guidance Manual [Internet], 2020 | 41 | 2020 |
Modeling small-molecule reactivity identifies promiscuous bioactive compounds MK Matlock, TB Hughes, JL Dahlin, SJ Swamidass Journal of chemical information and modeling 58 (8), 1483-1500, 2018 | 39 | 2018 |
Atomistic Simulations of CO2 and N2 Diffusion in Silica Zeolites: The Impact of Pore Size and Shape D Selassie, D Davis, J Dahlin, E Feise, G Haman, DS Sholl, D Kohen The Journal of Physical Chemistry C 112 (42), 16521-16531, 2008 | 35 | 2008 |
A cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylation JL Dahlin, R Sinville, J Solberg, H Zhou, J Han, S Francis, JM Strasser, ... PLoS One 8 (11), e78877, 2013 | 29 | 2013 |