| The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance F Han, CF Li, Z Cai, X Zhang, G Jin, WN Zhang, C Xu, CY Wang, J Morrow, ... Nature communications 9 (1), 4728, 2018 | 147 | 2018 |
| Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1 J Wu, X Zhang, L Zhang, CY Wu, AH Rezaelan, CH Chan, JM Li, J Wang, ... Molecular cell, 2012 | 141 | 2012 |
| Phosphorylation of PDHA by AMPK drives TCA cycle to promote cancer metastasis Z Cai, CF Li, F Han, C Liu, A Zhang, CC Hsu, D Peng, X Zhang, G Jin, ... Molecular cell 80 (2), 263-278. e7, 2020 | 136 | 2020 |
| Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress SW Lee, CF Li, G Jin, Z Cai, F Han, CH Chan, WL Yang, BK Li, ... Molecular cell 57 (6), 1022-1033, 2015 | 129 | 2015 |
| Skp2–MacroH2A1–CDK8 axis orchestrates G2/M transition and tumorigenesis D Xu, CF Li, X Zhang, Z Gong, CH Chan, SW Lee, G Jin, AH Rezaeian, ... Nature communications 6 (1), 6641, 2015 | 116 | 2015 |
| A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis AH Rezaeian, CF Li, CY Wu, X Zhang, J Delacerda, MJ You, F Han, Z Cai, ... Nature cell biology 19 (1), 38-51, 2017 | 103 | 2017 |
| Skp2-mediated RagA ubiquitination elicits a negative feedback to prevent amino-acid-dependent mTORC1 hyperactivation by recruiting GATOR1 G Jin, SW Lee, X Zhang, Z Cai, Y Gao, PC Chou, AH Rezaeian, F Han, ... Molecular cell 58 (6), 989-1000, 2015 | 79 | 2015 |
| TRAF6 restricts p53 mitochondrial translocation, apoptosis, and tumor suppression X Zhang, CF Li, L Zhang, CY Wu, L Han, G Jin, AH Rezaeian, F Han, ... Molecular cell 64 (4), 803-814, 2016 | 76 | 2016 |
| The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal J Wang, F Han, J Wu, SW Lee, CH Chan, CY Wu, WL Yang, Y Gao, ... Blood, The Journal of the American Society of Hematology 118 (20), 5429-5438, 2011 | 64 | 2011 |
| H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis X Zhang, B Li, AH Rezaeian, X Xu, PC Chou, G Jin, F Han, BS Pan, ... Nature communications 8 (1), 14799, 2017 | 48 | 2017 |
| Foxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex J Wu, SW Lee, X Zhang, F Han, SY Kwan, X Yuan, WL Yang, YS Jeong, ... Oncogene 32 (1), 78-85, 2013 | 41 | 2013 |
| SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling C Xu, G Jin, H Wu, W Cui, YH Wang, RK Manne, G Wang, W Zhang, ... The Journal of Clinical Investigation 132 (5), 2022 | 26 | 2022 |
| E3-ligase Skp2 regulates β-catenin expression and maintains hematopoietic stem cell homing J Wang, F Han, SW Lee, J Wu, CH Chan, X Zhang, Y Gao, HK Su, Z Feng, ... Biochemical and biophysical research communications 445 (3), 566-571, 2014 | 17 | 2014 |
| Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance C Liu, Z Cai, G Jin, D Peng, BS Pan, X Zhang, F Han, X Xu, HK Lin Cell discovery 4 (1), 54, 2018 | 16 | 2018 |
| Author Correction: A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1 [alpha] activation, tumorigenesis and metastasis. AH Rezaeian, CF Li, CY Wu, X Zhang, J Delacerda, MJ You, F Han Nature cell biology 22 (7), 907-908, 2020 | | 2020 |
| The role of Skp2 in hematopoietic stem cell quiescence, pool size and HK Lin, X Zhang, YS Jeong, A Moten, F Samaniego, P Huang, Q Liu, ... | | 2011 |
