Leigh Carmody
Leigh Carmody
Verifierad e-postadress på jax.org
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Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources
S Köhler, L Carmody, N Vasilevsky, JOB Jacobsen, D Danis, JP Gourdine, ...
Nucleic acids research 47 (D1), D1018-D1027, 2019
1662019
Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and α-actinin-2
AJ Robison, MA Bass, Y Jiao, LB MacMillan, LC Carmody, RK Bartlett, ...
Journal of Biological Chemistry 280 (42), 35329-35336, 2005
1412005
The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits
RT Terry-Lorenzo, LC Carmody, JW Voltz, JH Connor, S Li, FD Smith, ...
Journal of Biological Chemistry 277 (31), 27716-27724, 2002
872002
A protein phosphatase-1γ1 isoform selectivity determinant in dendritic spine-associated neurabin
LC Carmody, PA Bauman, MA Bass, N Mavila, AA DePaoli-Roach, ...
Journal of Biological Chemistry 279 (21), 21714-21723, 2004
522004
Identification of a selective small molecule inhibitor of breast cancer stem cells
AR Germain, LC Carmody, B Morgan, C Fernandez, E Forbeck, TA Lewis, ...
Bioorganic & medicinal chemistry letters 22 (10), 3571-3574, 2012
392012
Diversity-oriented synthesis yields a new drug lead for treatment of Chagas disease
S Dandapani, AR Germain, I Jewett, S le Quement, JC Marie, ...
ACS medicinal chemistry letters 5 (2), 149-153, 2014
372014
Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach
AJ Baucum, N Jalan-Sakrikar, Y Jiao, RM Gustin, LC Carmody, DL Tabb, ...
Molecular & Cellular Proteomics 9 (6), 1243-1259, 2010
322010
Selective targeting of the γ1 isoform of protein phosphatase 1 to F‐actin in intact cells requires multiple domains in spinophilin and neurabin
LC Carmody, AJ Baucum, MA Bass, RJ Colbran
The FASEB Journal 22 (6), 1660-1671, 2008
312008
Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell–like cells
LC Carmody, AR Germain, L VerPlank, PP Nag, B Muñoz, JR Perez, ...
Journal of biomolecular screening 17 (9), 1204-1210, 2012
292012
Analysis of specific interactions of native protein phosphatase 1 isoforms with targeting subunits
RJ Colbran, LC Carmody, PA Bauman, BE Wadzinski, MA Bass
Methods in enzymology 366, 156-175, 2003
292003
Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation
EC Dykhuizen, LC Carmody, N Tolliday, GR Crabtree, MAJ Palmer
Journal of biomolecular screening 17 (9), 1221-1230, 2012
242012
Plain-language medical vocabulary for precision diagnosis
NA Vasilevsky, ED Foster, ME Engelstad, L Carmody, M Might, ...
Nature genetics 50 (4), 474-476, 2018
172018
The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species
KA Shefchek, NL Harris, M Gargano, N Matentzoglu, D Unni, M Brush, ...
Nucleic acids research 48 (D1), D704-D715, 2020
142020
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells
AR Germain, LC Carmody, PP Nag, B Morgan, L VerPlank, C Fernandez, ...
Bioorganic & medicinal chemistry letters 23 (6), 1834-1838, 2013
142013
Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors
S Chattopadhyay, AL Stewart, S Mukherjee, C Huang, KA Hartwell, ...
Cell reports 10 (5), 755-770, 2015
132015
Identification of small-molecule inhibitors of Trypansoma cruzi replication
AR Germain, LC Carmody, C Dockendorff, C Galan-Rodriguez, ...
Bioorganic & medicinal chemistry letters 21 (23), 7197-7200, 2011
132011
Semantic integration of clinical laboratory tests from electronic health records for deep phenotyping and biomarker discovery
XA Zhang, A Yates, N Vasilevsky, JP Gourdine, TJ Callahan, LC Carmody, ...
NPJ digital medicine 2 (1), 1-9, 2019
82019
Identification of a selective small-molecule inhibitor of breast cancer stem cells—probe 2
LC Carmody, A Germain, B Morgan, L VerPlank, C Fernandez, Y Feng, ...
Probe Reports from the NIH Molecular Libraries Program [Internet], 2014
72014
Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection
LC Carmody, A Germain, D Barker, C Galan-Rodriguez, E Bettiol, ...
Probe reports from the NIH molecular libraries program [Internet], 2011
72011
Probe Reports from the NIH Molecular Libraries Program [Internet]
M Boxer, M Shen, C Tanega, M Tang, K Lai, D Auld
72010
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Artiklar 1–20