| Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus J Wang, Y Wu, C Ma, G Fiorin, J Wang, LH Pinto, RA Lamb, ML Klein, ... Proceedings of the National Academy of Sciences 110 (4), 1315-1320, 2013 | 187 | 2013 |
| Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel X Jing, C Ma, Y Ohigashi, FA Oliveira, TS Jardetzky, LH Pinto, RA Lamb Proceedings of the National Academy of Sciences 105 (31), 10967-10972, 2008 | 179 | 2008 |
| Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel C Ma, AL Polishchuk, Y Ohigashi, AL Stouffer, A Schön, E Magavern, ... Proceedings of the National Academy of Sciences 106 (30), 12283-12288, 2009 | 159 | 2009 |
| Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto, X Zhang, ... Cell research 30 (8), 678-692, 2020 | 148 | 2020 |
| Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2 J Wang, C Ma, G Fiorin, V Carnevale, T Wang, F Hu, RA Lamb, LH Pinto, ... Journal of the American Chemical Society 133 (32), 12834-12841, 2011 | 130 | 2011 |
| Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ... Journal of medicinal chemistry 56 (7), 2804-2812, 2013 | 96 | 2013 |
| Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus MD Duque, C Ma, E Torres, J Wang, L Naesens, J Juárez-Jiménez, ... Journal of medicinal chemistry 54 (8), 2646-2657, 2011 | 72 | 2011 |
| pH-induced conformational change of the influenza M2 protein C-terminal domain PA Nguyen, CS Soto, A Polishchuk, GA Caputo, CD Tatko, C Ma, ... Biochemistry 47 (38), 9934-9936, 2008 | 67 | 2008 |
| Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 … Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ... Journal of the American Chemical Society 136 (52), 17987-17995, 2014 | 66 | 2014 |
| The amphipathic helix of influenza A virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles KL Roberts, GP Leser, C Ma, RA Lamb Journal of virology 87 (18), 9973-9982, 2013 | 64 | 2013 |
| Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel J Wang, C Ma, Y Wu, RA Lamb, LH Pinto, WF DeGrado Journal of the American Chemical Society 133 (35), 13844-13847, 2011 | 59 | 2011 |
| Exploring the requirements for the hydrophobic scaffold and polar amine in inhibitors of M2 from influenza A virus J Wang, C Ma, V Balannik, LH Pinto, RA Lamb, WF DeGrado ACS medicinal chemistry letters 2 (4), 307-312, 2011 | 56 | 2011 |
| The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus AL Stouffer, C Ma, L Cristian, Y Ohigashi, RA Lamb, JD Lear, LH Pinto, ... Structure 16 (7), 1067-1076, 2008 | 56 | 2008 |
| Recent progress in designing inhibitors that target the drug‐resistant M2 proton channels from the influenza A viruses J Wang, F Li, C Ma Peptide Science 104 (4), 291-309, 2015 | 53 | 2015 |
| Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus C Ma, CS Soto, Y Ohigashi, A Taylor, V Bournas, B Glawe, MK Udo, ... Journal of Biological Chemistry 283 (23), 15921-15931, 2008 | 50 | 2008 |
| Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus M Rey-Carrizo, M Barniol-Xicota, C Ma, M Frigolé-Vivas, E Torres, ... Journal of medicinal chemistry 57 (13), 5738-5747, 2014 | 49 | 2014 |
| An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition Y Ohigashi, C Ma, X Jing, V Balannick, LH Pinto, RA Lamb Proceedings of the National Academy of Sciences 106 (44), 18775-18779, 2009 | 47 | 2009 |
| 3-Azatetracyclo[5.2.1.15,8.01,5]undecane Derivatives: From Wild-Type Inhibitors of the M2 Ion Channel of Influenza A Virus to Derivatives with Potent Activity … M Rey-Carrizo, E Torres, C Ma, M Barniol-Xicota, J Wang, Y Wu, ... Journal of medicinal chemistry 56 (22), 9265-9274, 2013 | 45 | 2013 |
| Expeditious lead optimization of isoxazole-containing influenza A virus M2-S31N inhibitors using the Suzuki–Miyaura cross-coupling reaction F Li, Y Hu, Y Wang, C Ma, J Wang Journal of medicinal chemistry 60 (4), 1580-1590, 2017 | 44 | 2017 |
| Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay AD Balgi, J Wang, DYH Cheng, C Ma, TA Pfeifer, Y Shimizu, HJ Anderson, ... PLoS One 8 (2), e55271, 2013 | 43 | 2013 |
Jun WangUniversity of ArizonaVerified email at email.arizona.edu
