Irene Papatheodorou
Irene Papatheodorou
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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
Open Targets: a platform for therapeutic target identification and validation
G Koscielny, P An, D Carvalho-Silva, JA Cham, L Fumis, R Gasparyan, ...
Nucleic acids research 45 (D1), D985-D994, 2017
Expression Atlas: gene and protein expression across multiple studies and organisms
I Papatheodorou, NA Fonseca, M Keays, YA Tang, E Barrera, W Bazant, ...
Nucleic acids research 46 (D1), D246-D251, 2018
Pan-cancer analysis of whole genomes
I The, TPCA of Whole, Genomes Consortium
Nature 578 (7793), 82, 2020
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
N Alic, TD Andrews, ME Giannakou, I Papatheodorou, C Slack, ...
Molecular systems biology 7 (1), 502, 2011
ArrayExpress update–from bulk to single-cell expression data
A Athar, A Füllgrabe, N George, H Iqbal, L Huerta, A Ali, C Snow, ...
Nucleic acids research 47 (D1), D711-D715, 2019
Ensembl genomes 2020—enabling non-vertebrate genomic research
KL Howe, B Contreras-Moreira, N De Silva, G Maslen, W Akanni, J Allen, ...
Nucleic acids research 48 (D1), D689-D695, 2020
Gramene 2018: unifying comparative genomics and pathway resources for plant research
MK Tello-Ruiz, S Naithani, JC Stein, P Gupta, M Campbell, A Olson, ...
Nucleic acids research 46 (D1), D1181-D1189, 2018
DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans
JMA Tullet, C Araiz, MJ Sanders, C Au, A Benedetto, I Papatheodorou, ...
PLOS Genetics, 2014
Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster
LP Nazif Alic, Maria E. Giannakou, Irene Papatheodorou, Matthew P. Hoddinott ...
PLOS Genetics, 2014
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer
HKM Vollan, OM Rueda, SF Chin, C Curtis, G Turashvili, S Shah, ...
Molecular oncology 9 (1), 115-127, 2015
Expression Atlas update: from tissues to single cells
I Papatheodorou, P Moreno, J Manning, AMP Fuentes, N George, ...
Nucleic Acids Research 48 (D1), D77-D83, 2020
Computational biology for ageing
D Wieser, I Papatheodorou, M Ziehm, JM Thornton
Philosophical Transactions of the Royal Society B: Biological Sciences 366 …, 2011
Inference of gene relations from microarray data by abduction
I Papatheodorou, A Kakas, M Sergot
International Conference on Logic Programming and Nonmonotonic Reasoning …, 2005
Linking gene expression to phenotypes via pathway information
I Papatheodorou, A Oellrich, D Smedley
Journal of Biomedical Semantics 6 (17), 2015
A metadata approach for clinical data management in translational genomics studies in breast cancer
I Papatheodorou, C Crichton, L Morris, P Maccallum, J Davies, ...
BMC medical genomics 2 (1), 66, 2009
MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans
M Riesen, I Feyst, N Rattanavirotkul, M Ezcurra, JMA Tullet, ...
Aging, 2014
Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing
I Papatheodorou, M Ziehm, D Wieser, N Alic, L Partridge, JM Thornton
PLoS One 7 (12), e50881, 2012
Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing
I Papatheodorou, R Petrovs, JMT Thornton
Bioinformatics, 2014
Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster
DK Ivanov, I Papatheodorou, M Ziehm, JM Thornton
Molecular BioSystems 9 (7), 1756-1764, 2013
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Artiklar 1–20