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James Canavan
James Canavan
Brigham & Women's Hospital, Boston MA, USA
Verifierad e-postadress på childrens.harvard.edu
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The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells
N Powell, AW Walker, E Stolarczyk, JB Canavan, MR Gökmen, E Marks, ...
Immunity 37 (4), 674-684, 2012
3622012
Infection and systemic inflammation, not ammonia, are associated with Grade 3/4 hepatic encephalopathy, but not mortality in cirrhosis
DL Shawcross, Y Sharifi, JB Canavan, AD Yeoman, RD Abeles, NJ Taylor, ...
Journal of hepatology 54 (4), 640-649, 2011
3122011
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
JB Canavan, C Scottā, A Vossenkämper, R Goldberg, MJ Elder, I Shoval, ...
Gut 65 (4), 584-594, 2016
2002016
CD 161 expression characterizes a subpopulation of human regulatory T cells that produces IL‐17 in a STAT 3‐dependent manner
B Afzali, PJ Mitchell, FC Edozie, GAM Povoleri, SE Dowson, L Demandt, ...
European journal of immunology 43 (8), 2043-2054, 2013
1522013
Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation
B Afzali, FC Edozie, H Fazekasova, C Scotta, PJ Mitchell, JB Canavan, ...
Clinical Journal of the American Society of Nephrology 8 (8), 1396-1405, 2013
1112013
Interleukin 6 increases production of cytokines by colonic innate lymphoid cells in mice and patients with chronic intestinal inflammation
N Powell, JW Lo, P Biancheri, A Vossenkämper, E Pantazi, AW Walker, ...
Gastroenterology 149 (2), 456-467. e15, 2015
972015
Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet
E Stolarczyk, CT Vong, E Perucha, I Jackson, MA Cawthorne, ET Wargent, ...
Cell metabolism 17 (4), 520-533, 2013
942013
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy
JB Canavan, B Afzali, C Scottā, H Fazekasova, FC Edozie, TT Macdonald, ...
Blood, The Journal of the American Society of Hematology 119 (8), e57-e66, 2012
932012
Determining the economic cost of ICU treatment: a prospective “micro-costing” study
AM McLaughlin, J Hardt, JB Canavan, MB Donnelly
Intensive care medicine 35, 2135-2140, 2009
682009
Molecular comparison of adult and pediatric ulcerative colitis indicates broad similarity of molecular pathways in disease tissue
K Li, R Strauss, J Ouahed, D Chan, SE Telesco, DS Shouval, JB Canavan, ...
Journal of pediatric gastroenterology and nutrition 67 (1), 45-52, 2018
512018
Relative resistance of human CD4+ memory T cells to suppression by CD4+ CD25+ regulatory T cells
B Afzali, PJ Mitchell, C Scotta, J Canavan, FC Edozie, H Fazekasova, ...
American Journal of Transplantation 11 (8), 1734-1742, 2011
452011
High-dimensional immune phenotyping and transcriptional analyses reveal robust recovery of viable human immune and epithelial cells from frozen gastrointestinal tissue
L Konnikova, G Boschetti, A Rahman, V Mitsialis, J Lord, C Richmond, ...
Mucosal immunology 11 (6), 1684-1693, 2018
392018
Transcriptional regulation of the mucosal immune system mediated by T-bet
N Powell, JB Canavan, TT MacDonald, GM Lord
Mucosal immunology 3 (6), 567-577, 2010
332010
Low-dose interleukin-2 ameliorates colitis in a preclinical humanized mouse model
JA Goettel, D Kotlarz, R Emani, JB Canavan, L Konnikova, D Illig, SM Frei, ...
Cellular and Molecular Gastroenterology and Hepatology 8 (2), 193-195, 2019
292019
Significant psychological morbidity occurs in irritable bowel syndrome: a case‐control study using a pharmacy reimbursement database
JB Canavan, K Bennett, J Feely, CA O’MORÁIN, HJ O’CONNOR
Alimentary pharmacology & therapeutics 29 (4), 440-449, 2009
272009
Full, partial, and modified permutations of the Mayo score: characterizing clinical and patient-reported outcomes in ulcerative colitis patients
AN Naegeli, T Hunter, Y Dong, B Hoskin, C Middleton-Dalby, ...
Crohn's & Colitis 360 3 (1), otab007, 2021
222021
A survey of MRSA awareness and knowledge among the general public and patients' visitors
AM McLaughlin, JB Canavan, EJ Adams, R McDonagh, H Brar, ...
British Journal of Infection Control 9 (5), 18-23, 2008
182008
DOP42 Efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with moderately-to-severely active Ulcerative Colitis: 12-week results …
S Danese, R Panaccione, G D’Haens, L Peyrin-Biroulet, S Schreiber, ...
Journal of Crohn's and Colitis 16 (Supplement_1), i091-i092, 2022
152022
Immunologic alterations associated with oral delivery of anti-CD3 (OKT3) monoclonal antibodies in patients with moderate-to-severe ulcerative colitis
EK Boden, JB Canavan, CJ Moran, K McCann, WA Dunn, FA Farraye, ...
Crohn's & Colitis 360 1 (2), otz009, 2019
142019
Artificial intelligence in inflammatory bowel disease endoscopy: implications for clinical trials
HA Ahmad, JE East, R Panaccione, S Travis, JB Canavan, K Usiskin, ...
Journal of Crohn's and Colitis 17 (8), 1342-1353, 2023
122023
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