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Xiaomeng Shen
Xiaomeng Shen
Verifierad e-postadress på merck.com
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Brief myocardial ischemia produces cardiac troponin I release and focal myocyte apoptosis in the absence of pathological infarction in swine
BR Weil, RF Young, X Shen, G Suzuki, J Qu, S Malhotra, JM Canty Jr
Basic to Translational Science 2 (2), 105-114, 2017
1222017
IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts
X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, DJ Poulsen, BC Orsburn, ...
Proceedings of the National Academy of Sciences 115 (21), E4767-E4776, 2018
802018
An IonStar experimental strategy for MS1 ion current-based quantification using ultrahigh-field orbitrap: reproducible, in-depth, and accurate protein measurement in large cohorts
X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, B Orsburn, J Wang, J Qu
Journal of proteome research 16 (7), 2445-2456, 2017
742017
Large-scale, ion-current-based proteomics investigation of bronchoalveolar lavage fluid in chronic obstructive pulmonary disease patients
C Tu, MJ Mammen, J Li, X Shen, X Jiang, Q Hu, J Wang, S Sethi, J Qu
Journal of proteome research 13 (2), 627-639, 2014
722014
Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry
M Qu, B An, S Shen, M Zhang, X Shen, X Duan, JP Balthasar, J Qu
Mass Spectrometry Reviews 36 (6), 734-754, 2017
642017
Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by …
E Nouri-Nigjeh, S Sukumaran, C Tu, J Li, X Shen, X Duan, DC DuBois, ...
Analytical chemistry 86 (16), 8149-8157, 2014
412014
Optimization of search engines and postprocessing approaches to maximize peptide and protein identification for high-resolution mass data
C Tu, Q Sheng, J Li, D Ma, X Shen, X Wang, Y Shyr, Z Yi, J Qu
Journal of proteome research 14 (11), 4662-4673, 2015
382015
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs
N Bai, KM Riching, A Makaju, H Wu, TM Acker, SC Ou, Y Zhang, X Shen, ...
Journal of Biological Chemistry 298 (4), 2022
342022
Proteomic profiling of the retinas in a neonatal rat model of oxygen-induced retinopathy with a reproducible ion-current-based MS1 approach
C Tu, KD Beharry, X Shen, J Li, L Wang, JV Aranda, J Qu
Journal of proteome research 14 (5), 2109-2120, 2015
292015
Quantitative proteomics in cardiovascular research: global and targeted strategies
X Shen, R Young, JM Canty, J Qu
PROTEOMICS–Clinical Applications 8 (7-8), 488-505, 2014
292014
Experimental null method to guide the development of technical procedures and to control false-positive discovery in quantitative proteomics
X Shen, Q Hu, J Li, J Wang, J Qu
Journal of proteome research 14 (10), 4147-4157, 2015
252015
Reproducible ion-current-based approach for 24-plex comparison of the tissue proteomes of hibernating versus normal myocardium in swine models
J Qu, R Young, BJ Page, X Shen, N Tata, J Li, X Duan, JA Fallavollita, ...
Journal of proteome research 13 (5), 2571-2584, 2014
232014
Temporal effects of combined birinapant and paclitaxel on pancreatic cancer cells investigated via large-scale, ion-current-based quantitative proteomics (IonStar)
X Wang, J Niu, J Li, X Shen, S Shen, RM Straubinger, J Qu
Molecular & Cellular Proteomics 17 (4), 655-671, 2018
212018
ICan: An optimized ion-current-based quantification procedure with enhanced quantitative accuracy and sensitivity in biomarker discovery
C Tu, Q Sheng, J Li, X Shen, M Zhang, Y Shyr, J Qu
Journal of proteome research 13 (12), 5888-5897, 2014
212014
Multi‐scale network model supported by proteomics for analysis of combined gemcitabine and birinapant effects in pancreatic cancer cells
X Zhu, X Shen, J Qu, RM Straubinger, WJ Jusko
CPT: Pharmacometrics & Systems Pharmacology 7 (9), 549-561, 2018
202018
Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics
K Kamisoglu, S Sukumaran, E Nouri-Nigjeh, C Tu, J Li, X Shen, X Duan, ...
Omics: a journal of integrative biology 19 (2), 80-91, 2015
202015
Proteomic analysis of combined gemcitabine and birinapant in pancreatic cancer cells
X Zhu, X Shen, J Qu, RM Straubinger, WJ Jusko
Frontiers in Pharmacology 9, 317287, 2018
172018
Ion-current-based temporal proteomic profiling of influenza-a-virus-infected mouse lungs revealed underlying mechanisms of altered integrity of the lung microvascular barrier
S Shen, J Li, S Hilchey, X Shen, C Tu, X Qiu, A Ng, S Ghaemmaghami, ...
Journal of proteome research 15 (2), 540-553, 2016
152016
Quantitative proteomic and phosphoproteomic profiling of ischemic myocardial stunning in swine
X Wang, X Shen, BR Weil, RF Young, JM Canty, J Qu
American Journal of Physiology-Heart and Circulatory Physiology 318 (5 …, 2020
72020
New insights into the disease progression control mechanisms by comparing long-term-nonprogressors versus normal-progressors among HIV-1-positive patients using an ion current …
X Shen, B Nair, SD Mahajan, X Jiang, J Li, S Shen, C Tu, C Hsiao, ...
Journal of Proteome Research 14 (12), 5225-5239, 2015
72015
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Artiklar 1–20