Brief myocardial ischemia produces cardiac troponin I release and focal myocyte apoptosis in the absence of pathological infarction in swine BR Weil, RF Young, X Shen, G Suzuki, J Qu, S Malhotra, JM Canty Jr Basic to Translational Science 2 (2), 105-114, 2017 | 122 | 2017 |
IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, DJ Poulsen, BC Orsburn, ... Proceedings of the National Academy of Sciences 115 (21), E4767-E4776, 2018 | 80 | 2018 |
An IonStar experimental strategy for MS1 ion current-based quantification using ultrahigh-field orbitrap: reproducible, in-depth, and accurate protein measurement in large cohorts X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, B Orsburn, J Wang, J Qu Journal of proteome research 16 (7), 2445-2456, 2017 | 74 | 2017 |
Large-scale, ion-current-based proteomics investigation of bronchoalveolar lavage fluid in chronic obstructive pulmonary disease patients C Tu, MJ Mammen, J Li, X Shen, X Jiang, Q Hu, J Wang, S Sethi, J Qu Journal of proteome research 13 (2), 627-639, 2014 | 72 | 2014 |
Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry M Qu, B An, S Shen, M Zhang, X Shen, X Duan, JP Balthasar, J Qu Mass Spectrometry Reviews 36 (6), 734-754, 2017 | 64 | 2017 |
Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by … E Nouri-Nigjeh, S Sukumaran, C Tu, J Li, X Shen, X Duan, DC DuBois, ... Analytical chemistry 86 (16), 8149-8157, 2014 | 41 | 2014 |
Optimization of search engines and postprocessing approaches to maximize peptide and protein identification for high-resolution mass data C Tu, Q Sheng, J Li, D Ma, X Shen, X Wang, Y Shyr, Z Yi, J Qu Journal of proteome research 14 (11), 4662-4673, 2015 | 38 | 2015 |
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs N Bai, KM Riching, A Makaju, H Wu, TM Acker, SC Ou, Y Zhang, X Shen, ... Journal of Biological Chemistry 298 (4), 2022 | 34 | 2022 |
Proteomic profiling of the retinas in a neonatal rat model of oxygen-induced retinopathy with a reproducible ion-current-based MS1 approach C Tu, KD Beharry, X Shen, J Li, L Wang, JV Aranda, J Qu Journal of proteome research 14 (5), 2109-2120, 2015 | 29 | 2015 |
Quantitative proteomics in cardiovascular research: global and targeted strategies X Shen, R Young, JM Canty, J Qu PROTEOMICS–Clinical Applications 8 (7-8), 488-505, 2014 | 29 | 2014 |
Experimental null method to guide the development of technical procedures and to control false-positive discovery in quantitative proteomics X Shen, Q Hu, J Li, J Wang, J Qu Journal of proteome research 14 (10), 4147-4157, 2015 | 25 | 2015 |
Reproducible ion-current-based approach for 24-plex comparison of the tissue proteomes of hibernating versus normal myocardium in swine models J Qu, R Young, BJ Page, X Shen, N Tata, J Li, X Duan, JA Fallavollita, ... Journal of proteome research 13 (5), 2571-2584, 2014 | 23 | 2014 |
Temporal effects of combined birinapant and paclitaxel on pancreatic cancer cells investigated via large-scale, ion-current-based quantitative proteomics (IonStar) X Wang, J Niu, J Li, X Shen, S Shen, RM Straubinger, J Qu Molecular & Cellular Proteomics 17 (4), 655-671, 2018 | 21 | 2018 |
ICan: An optimized ion-current-based quantification procedure with enhanced quantitative accuracy and sensitivity in biomarker discovery C Tu, Q Sheng, J Li, X Shen, M Zhang, Y Shyr, J Qu Journal of proteome research 13 (12), 5888-5897, 2014 | 21 | 2014 |
Multi‐scale network model supported by proteomics for analysis of combined gemcitabine and birinapant effects in pancreatic cancer cells X Zhu, X Shen, J Qu, RM Straubinger, WJ Jusko CPT: Pharmacometrics & Systems Pharmacology 7 (9), 549-561, 2018 | 20 | 2018 |
Tandem analysis of transcriptome and proteome changes after a single dose of corticosteroid: a systems approach to liver function in pharmacogenomics K Kamisoglu, S Sukumaran, E Nouri-Nigjeh, C Tu, J Li, X Shen, X Duan, ... Omics: a journal of integrative biology 19 (2), 80-91, 2015 | 20 | 2015 |
Proteomic analysis of combined gemcitabine and birinapant in pancreatic cancer cells X Zhu, X Shen, J Qu, RM Straubinger, WJ Jusko Frontiers in Pharmacology 9, 317287, 2018 | 17 | 2018 |
Ion-current-based temporal proteomic profiling of influenza-a-virus-infected mouse lungs revealed underlying mechanisms of altered integrity of the lung microvascular barrier S Shen, J Li, S Hilchey, X Shen, C Tu, X Qiu, A Ng, S Ghaemmaghami, ... Journal of proteome research 15 (2), 540-553, 2016 | 15 | 2016 |
Quantitative proteomic and phosphoproteomic profiling of ischemic myocardial stunning in swine X Wang, X Shen, BR Weil, RF Young, JM Canty, J Qu American Journal of Physiology-Heart and Circulatory Physiology 318 (5 …, 2020 | 7 | 2020 |
New insights into the disease progression control mechanisms by comparing long-term-nonprogressors versus normal-progressors among HIV-1-positive patients using an ion current … X Shen, B Nair, SD Mahajan, X Jiang, J Li, S Shen, C Tu, C Hsiao, ... Journal of Proteome Research 14 (12), 5225-5239, 2015 | 7 | 2015 |