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Timour Baslan
Timour Baslan
Verified email at vet.upenn.edu
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Cited by
Year
Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy
J Li, KT Byrne, F Yan, T Yamazoe, Z Chen, T Baslan, LP Richman, JH Lin, ...
Immunity 49 (1), 178-193. e7, 2018
5712018
Genome-wide copy number analysis of single cells
T Baslan, J Kendall, L Rodgers, H Cox, M Riggs, A Stepansky, J Troge, ...
Nature protocols 7 (6), 1024-1041, 2012
3892012
Unravelling biology and shifting paradigms in cancer with single-cell sequencing
T Baslan, J Hicks
Nature Reviews Cancer 17 (9), 557-569, 2017
3222017
p53 represses the mevalonate pathway to mediate tumor suppression
SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ...
Cell 176 (3), 564-580. e19, 2019
3162019
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ...
Science 362 (6421), 1416-1422, 2018
2872018
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms
Y Liu, C Chen, Z Xu, C Scuoppo, CD Rillahan, J Gao, B Spitzer, ...
Nature 531 (7595), 471-475, 2016
2612016
Interactive analysis and assessment of single-cell copy-number variations
T Garvin, R Aboukhalil, J Kendall, T Baslan, GS Atwal, J Hicks, M Wigler, ...
Nature methods 12 (11), 1058-1060, 2015
2472015
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
KP O'Rourke, E Loizou, G Livshits, EM Schatoff, T Baslan, E Manchado, ...
Nature biotechnology 35 (6), 577-582, 2017
2182017
α-Ketoglutarate links p53 to cell fate during tumour suppression
JP Morris IV, JJ Yashinskie, R Koche, R Chandwani, S Tian, CC Chen, ...
Nature 573 (7775), 595-599, 2019
2162019
Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line
M Nattestad, S Goodwin, K Ng, T Baslan, FJ Sedlazeck, P Rescheneder, ...
Genome research 28 (8), 1126-1135, 2018
1632018
An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer
Y Xue, L Martelotto, T Baslan, A Vides, M Solomon, TT Mai, N Chaudhary, ...
Nature medicine 23 (8), 929-937, 2017
1602017
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells
AE Dago, A Stepansky, A Carlsson, M Luttgen, J Kendall, T Baslan, ...
PloS one 9 (8), e101777, 2014
1582014
The genomic landscape of male breast cancers
S Piscuoglio, CKY Ng, MP Murray, E Guerini-Rocco, LG Martelotto, ...
Clinical Cancer Research 22 (16), 4045-4056, 2016
1512016
DNAJB1–PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma
ER Kastenhuber, G Lalazar, SL Houlihan, DF Tschaharganeh, T Baslan, ...
Proceedings of the National Academy of Sciences 114 (50), 13076-13084, 2017
1462017
Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples
LG Martelotto, T Baslan, J Kendall, FC Geyer, KA Burke, L Spraggon, ...
Nature medicine 23 (3), 376-385, 2017
1352017
Optimizing sparse sequencing of single cells for highly multiplex copy number profiling
T Baslan, J Kendall, B Ward, H Cox, A Leotta, L Rodgers, M Riggs, ...
Genome research 25 (5), 714-724, 2015
1272015
Ordered and deterministic cancer genome evolution after p53 loss
T Baslan, JP Morris IV, Z Zhao, J Reyes, YJ Ho, KM Tsanov, J Bermeo, ...
Nature 608 (7924), 795-802, 2022
1142022
Cohesin members Stag1 and Stag2 display distinct roles in chromatin accessibility and topological control of HSC self-renewal and differentiation
AD Viny, RL Bowman, Y Liu, VP Lavallée, SE Eisman, W Xiao, ...
Cell stem cell 25 (5), 682-696. e8, 2019
1122019
Replication timing maintains the global epigenetic state in human cells
KN Klein, PA Zhao, X Lyu, T Sasaki, DA Bartlett, AM Singh, I Tasan, ...
Science 372 (6540), 371-378, 2021
1092021
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis
K Hatzi, H Geng, AS Doane, C Meydan, R LaRiviere, M Cardenas, C Duy, ...
Nature immunology 20 (1), 86-96, 2019
742019
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