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Amy Kiernan
Amy Kiernan
University of Rochester Medical Center
Verifierad e-postadress på urmc.rochester.edu
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A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse
PM Nolan, J Peters, M Strivens, D Rogers, J Hagan, N Spurr, IC Gray, ...
Nature genetics 25 (4), 440-443, 2000
7572000
Sox2 is required for sensory organ development in the mammalian inner ear
AE Kiernan, AL Pelling, KKH Leung, ASP Tang, DM Bell, C Tease, ...
Nature 434 (7036), 1031-1035, 2005
5852005
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear
AE Kiernan, J Xu, T Gridley
PLoS genetics 2 (1), e4, 2006
3322006
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear
AE Kiernan, R Cordes, R Kopan, A Gossler, T Gridley
Oxford University Press for The Company of Biologists Limited 132 (19), 4353 …, 2005
3082005
The Notch ligand Jagged1 is required for inner ear sensory development
AE Kiernan, N Ahituv, H Fuchs, R Balling, KB Avraham, KP Steel, ...
Proceedings of the National Academy of Sciences 98 (7), 3873-3878, 2001
2482001
Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice
M Hulander, AE Kiernan, SR Blomqvist, P Carlsson, EJ Samuelsson, ...
Oxford University Press for The Company of Biologists Limited 130 (9), 2013-2025, 2003
2042003
Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells
K Liu, M Jiang, Y Lu, H Chen, J Sun, S Wu, WY Ku, H Nakagawa, Y Kita, ...
Cell stem cell 12 (3), 304-315, 2013
1982013
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
H Tsai, RE Hardisty, C Rhodes, AE Kiernan, P Roby, ...
Human molecular genetics 10 (5), 507-512, 2001
1552001
Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear
W Pan, Y Jin, B Stanger, AE Kiernan
Proceedings of the National Academy of Sciences 107 (36), 15798-15803, 2010
1492010
Molecular genetics of pattern formation in the inner ear: do compartment boundaries play a role?
JV Brigande, AE Kiernan, X Gao, LE Iten, DM Fekete
Proceedings of the National Academy of Sciences 97 (22), 11700-11706, 2000
1382000
Notch signaling during cell fate determination in the inner ear
AE Kiernan
Seminars in cell & developmental biology 24 (5), 470-479, 2013
1152013
Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear
W Pan, Y Jin, J Chen, RJ Rottier, KP Steel, AE Kiernan
Journal of Neuroscience 33 (41), 16146-16157, 2013
1022013
Targeting Notch‐activated M1 macrophages attenuates joint tissue damage in a mouse model of inflammatory arthritis
W Sun, H Zhang, H Wang, YG Chiu, M Wang, CT Ritchlin, A Kiernan, ...
Journal of Bone and Mineral Research 32 (7), 1469-1480, 2017
862017
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities
KA Fernandes, JM Harder, PA Williams, RL Rausch, AE Kiernan, KS Nair, ...
Experimental eye research 141, 42-56, 2015
842015
ENU mutagenesis reveals a highly mutable locus on mouse Chromosome 4 that affects ear morphogenesis
AE Kiernan, A Erven, S Voegeling, J Peters, P Nolan, J Hunter, Y Bacon, ...
Mammalian genome 13, 142-148, 2002
602002
The expression domain of two related homeobox genes defines a compartment in the chicken inner ear that may be involved in semicircular canal formation
AE Kiernan, F Nunes, DK Wu, DM Fekete
Developmental biology 191 (2), 215-229, 1997
571997
Development of the mouse inner ear
AE Kiernan
Mouse development: Patterning, morphogenesis and organogenesis, 2001
552001
SOX2 is required for inner ear neurogenesis
AR Steevens, DL Sookiasian, JC Glatzer, AE Kiernan
Scientific reports 7 (1), 4086, 2017
542017
Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye
Y Zhou, C Tanzie, Z Yan, S Chen, M Duncan, K Gaudenz, H Li, C Seidel, ...
Proceedings of the National Academy of Sciences 110 (22), 8966-8971, 2013
492013
SOX2 is required for inner ear growth and cochlear nonsensory formation before sensory development
AR Steevens, JC Glatzer, CC Kellogg, WC Low, PA Santi, AE Kiernan
Development 146 (13), dev170522, 2019
452019
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Artiklar 1–20