| SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism B Ponugoti, DH Kim, Z Xiao, Z Smith, J Miao, M Zang, SY Wu, CM Chiang, ... Journal of Biological Chemistry 285 (44), 33959-33970, 2010 | 565 | 2010 |
| FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states JK Kemper, Z Xiao, B Ponugoti, J Miao, S Fang, D Kanamaluru, S Tsang, ... Cell metabolism 10 (5), 392-404, 2009 | 352 | 2009 |
| Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis J Miao, AV Ling, PV Manthena, ME Gearing, MJ Graham, RM Crooke, ... Nature communications 6 (1), 6498, 2015 | 344 | 2015 |
| A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition J Lee, A Padhye, A Sharma, G Song, J Miao, YY Mo, L Wang, JK Kemper Journal of Biological Chemistry 285 (17), 12604-12611, 2010 | 282 | 2010 |
| Frizzled proteins are colonic epithelial receptors for C. difficile toxin B L Tao, J Zhang, P Meraner, A Tovaglieri, X Wu, R Gerhard, X Zhang, ... Nature 538 (7625), 350-355, 2016 | 276 | 2016 |
| Trimethylamine N-oxide binds and activates PERK to promote metabolic dysfunction S Chen, A Henderson, MC Petriello, KA Romano, M Gearing, J Miao, ... Cell metabolism 30 (6), 1141-1151. e5, 2019 | 254 | 2019 |
| Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for … J Miao, S Fang, Y Bae, JK Kemper Journal of Biological Chemistry 281 (21), 14537-14546, 2006 | 250 | 2006 |
| Differential Regulation of Rat and Human CYP7A1 by the Nuclear Oxysterol Receptor Liver X Receptor-α B Goodwin, MA Watson, H Kim, J Miao, JK Kemper, SA Kliewer Molecular endocrinology 17 (3), 386-394, 2003 | 239 | 2003 |
| Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression JT Haas, J Miao, D Chanda, Y Wang, E Zhao, ME Haas, M Hirschey, ... Cell metabolism 15 (6), 873-884, 2012 | 217 | 2012 |
| Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer M Wang, J Liu, Y Zhao, R He, X Xu, X Guo, X Li, S Xu, J Miao, J Guo, ... Molecular cancer 19, 1-15, 2020 | 157 | 2020 |
| Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin–proteasomal degradation J Miao, Z Xiao, D Kanamaluru, G Min, PM Yau, TD Veenstra, E Ellis, ... Genes & development 23 (8), 986-996, 2009 | 144 | 2009 |
| MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes CL Kurtz, BCE Peck, EE Fannin, C Beysen, J Miao, SR Landstreet, S Ding, ... Diabetes 63 (9), 3141-3148, 2014 | 130 | 2014 |
| Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP JK Kemper, H Kim, J Miao, S Bhalla, Y Bae Molecular and cellular biology 24 (17), 7707-7719, 2004 | 118 | 2004 |
| Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism S Fang, J Miao, L Xiang, B Ponugoti, E Treuter, JK Kemper Molecular and cellular biology 27 (4), 1407-1424, 2007 | 115 | 2007 |
| Role of insulin in the regulation of proprotein convertase subtilisin/kexin type 9 J Miao, PV Manthena, ME Haas, AV Ling, DJ Shin, MJ Graham, ... Arteriosclerosis, thrombosis, and vascular biology 35 (7), 1589-1596, 2015 | 101 | 2015 |
| Inactivating hepatic follistatin alleviates hyperglycemia R Tao, C Wang, O Stöhr, W Qiu, Y Hu, J Miao, XC Dong, S Leng, ... Nature medicine 24 (7), 1058-1069, 2018 | 92 | 2018 |
| YAP suppresses gluconeogenic gene expression through PGC1α Y Hu, DJ Shin, H Pan, Z Lin, JM Dreyfuss, FD Camargo, J Miao, ... Hepatology 66 (6), 2029-2041, 2017 | 62 | 2017 |
| Beta-catenin causes adrenal hyperplasia by blocking zonal transdifferentiation E Pignatti, S Leng, Y Yuchi, KS Borges, NA Guagliardo, MS Shah, ... Cell Reports 31 (3), 2020 | 55 | 2020 |
| Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes J Miao, SE Choi, SM Seok, L Yang, WJ Zuercher, Y Xu, TM Willson, ... Molecular endocrinology 25 (7), 1159-1169, 2011 | 50 | 2011 |
| Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis J Miao, S Fang, J Lee, C Comstock, KE Knudsen, JK Kemper Molecular and cellular biology 29 (23), 6170-6181, 2009 | 46 | 2009 |
David BreaultAssociate Professor of Pediatrics, Harvard Medical SchoolVerified email at childrens.harvard.edu
