| Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs P Matsson, JM Pedersen, U Norinder, CAS Bergström, P Artursson Pharmaceutical research 26, 1816-1831, 2009 | 350 | 2009 |
| Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver X Chu, K Korzekwa, R Elsby, K Fenner, A Galetin, Y Lai, P Matsson, ... Clinical Pharmacology & Therapeutics 94 (1), 126-141, 2013 | 247 | 2013 |
| Cell permeability beyond the rule of 5 P Matsson, BC Doak, B Over, J Kihlberg Advanced drug delivery reviews 101, 42-61, 2016 | 222 | 2016 |
| Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1 G Ahlin, J Karlsson, JM Pedersen, L Gustavsson, R Larsson, P Matsson, ... Journal of medicinal chemistry 51 (19), 5932-5942, 2008 | 212 | 2008 |
| How big is too big for cell permeability? P Matsson, J Kihlberg Journal of Medicinal Chemistry 60 (5), 1662-1664, 2017 | 198 | 2017 |
| Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5 M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ... Journal of Medicinal Chemistry 61 (9), 4189-4202, 2018 | 168 | 2018 |
| Profiling of a prescription drug library for potential renal drug–drug interactions mediated by the organic cation transporter 2 Y Kido, P Matsson, KM Giacomini Journal of medicinal chemistry 54 (13), 4548-4558, 2011 | 167 | 2011 |
| Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11) JM Pedersen, P Matsson, CAS Bergström, J Hoogstraate, A Norén, ... toxicological sciences 136 (2), 328-343, 2013 | 165 | 2013 |
| Structural and conformational determinants of macrocycle cell permeability B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ... Nature Chemical Biology 12 (12), 1065-1074, 2016 | 160 | 2016 |
| Exploring the role of different drug transport routes in permeability screening P Matsson, CAS Bergström, N Nagahara, S Tavelin, U Norinder, ... Journal of medicinal chemistry 48 (2), 604-613, 2005 | 148 | 2005 |
| Rapid measurement of intracellular unbound drug concentrations A Mateus, P Matsson, P Artursson Molecular pharmaceutics 10 (6), 2467-2478, 2013 | 147 | 2013 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2) JM Pedersen, P Matsson, CAS Bergström, U Norinder, J Hoogstraate, ... Journal of medicinal chemistry 51 (11), 3275-3287, 2008 | 144 | 2008 |
| A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2) P Matsson, G Englund, G Ahlin, CAS Bergström, U Norinder, P Artursson Journal of Pharmacology and Experimental Therapeutics 323 (1), 19-30, 2007 | 144 | 2007 |
| Comparison of human solute carriers A Schlessinger, P Matsson, JE Shima, U Pieper, SW Yee, L Kelly, ... Protein Science 19 (3), 412-428, 2010 | 131 | 2010 |
| Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches Y Guo, X Chu, NJ Parrott, KLR Brouwer, V Hsu, S Nagar, P Matsson, ... Clinical Pharmacology & Therapeutics 104 (5), 865-889, 2018 | 89 | 2018 |
| Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties B Over, P McCarren, P Artursson, M Foley, F Giordanetto, G Grönberg, ... Journal of medicinal chemistry 57 (6), 2746-2754, 2014 | 85 | 2014 |
| Prediction of intracellular exposure bridges the gap between target-and cell-based drug discovery A Mateus, LJ Gordon, GJ Wayne, H Almqvist, H Axelsson, ... Proceedings of the National Academy of Sciences 114 (30), E6231-E6239, 2017 | 81 | 2017 |
| Intracellular drug bioavailability: a new predictor of system dependent drug disposition A Mateus, A Treyer, C Wegler, M Karlgren, P Matsson, P Artursson Scientific reports 7 (1), 43047, 2017 | 71 | 2017 |
| The proteome of filter-grown Caco-2 cells with a focus on proteins involved in drug disposition M Ölander, JR Wiśniewski, P Matsson, P Lundquist, P Artursson Journal of pharmaceutical sciences 105 (2), 817-827, 2016 | 71 | 2016 |
| Complete knockout of endogenous Mdr1 (Abcb1) in MDCK cells by CRISPR-Cas9 I Simoff, M Karlgren, M Backlund, AC Lindström, FZ Gaugaz, P Matsson, ... Journal of pharmaceutical sciences 105 (2), 1017-1021, 2016 | 60 | 2016 |
Per ArturssonUppsala universityVerified email at farmaci.uu.se
