Pär Matsson
Pär Matsson
Professor of Pharmacokinetics, Sahlgrenska Academy, University of Gothenburg
Verified email at gu.se
TitleCited byYear
Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs
P Matsson, JM Pedersen, U Norinder, CAS Bergström, P Artursson
Pharmaceutical research 26 (8), 1816-1831, 2009
Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver
X Chu, K Korzekwa, R Elsby, K Fenner, A Galetin, Y Lai, P Matsson, ...
Clinical Pharmacology & Therapeutics 94 (1), 126-141, 2013
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1
G Ahlin, J Karlsson, JM Pedersen, L Gustavsson, R Larsson, P Matsson, ...
Journal of medicinal chemistry 51 (19), 5932-5942, 2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)
JM Pedersen, P Matsson, CAS Bergström, U Norinder, J Hoogstraate, ...
Journal of medicinal chemistry 51 (11), 3275-3287, 2008
Exploring the role of different drug transport routes in permeability screening
P Matsson, CAS Bergström, N Nagahara, S Tavelin, U Norinder, ...
Journal of medicinal chemistry 48 (2), 604-613, 2005
A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2)
P Matsson, G Englund, G Ahlin, CAS Bergström, U Norinder, P Artursson
Journal of Pharmacology and Experimental Therapeutics 323 (1), 19-30, 2007
Profiling of a prescription drug library for potential renal drug–drug interactions mediated by the organic cation transporter 2
Y Kido, P Matsson, KM Giacomini
Journal of medicinal chemistry 54 (13), 4548-4558, 2011
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11)
JM Pedersen, P Matsson, CAS Bergström, J Hoogstraate, A Norén, ...
toxicological sciences 136 (2), 328-343, 2013
Comparison of human solute carriers
A Schlessinger, P Matsson, JE Shima, U Pieper, SW Yee, L Kelly, ...
Protein Science 19 (3), 412-428, 2010
Rapid measurement of intracellular unbound drug concentrations
A Mateus, P Matsson, P Artursson
Molecular pharmaceutics 10 (6), 2467-2478, 2013
Cell permeability beyond the rule of 5
P Matsson, BC Doak, B Over, J Kihlberg
Advanced drug delivery reviews 101, 42-61, 2016
Structural and conformational determinants of macrocycle cell permeability
B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ...
Nature chemical biology 12 (12), 1065, 2016
Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties
B Over, P McCarren, P Artursson, M Foley, F Giordanetto, G Grönberg, ...
Journal of medicinal chemistry 57 (6), 2746-2754, 2014
Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation
SE Hesselson, P Matsson, JE Shima, H Fukushima, SW Yee, ...
PloS one 4 (9), e6942, 2009
Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5
M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ...
Journal of medicinal chemistry 61 (9), 4189-4202, 2018
Intracellular drug bioavailability: a new predictor of system dependent drug disposition
A Mateus, A Treyer, C Wegler, M Karlgren, P Matsson, P Artursson
Scientific reports 7, 43047, 2017
Pharmacokinetic profiling in drug research: biological, physicochemical, and computational strategies
B Testa, SD Krämer, H Wunderli-Allenspach, G Folkers
Verlag Helvetica Chimica Acta, 2006
The proteome of filter-grown Caco-2 cells with a focus on proteins involved in drug disposition
M Ölander, JR Wiśniewski, P Matsson, P Lundquist, P Artursson
Journal of pharmaceutical sciences 105 (2), 817-827, 2016
Quantifying the impact of transporters on cellular drug permeability
P Matsson, LA Fenu, P Lundquist, JR Wiśniewski, M Kansy, P Artursson
Trends in pharmacological sciences 36 (5), 255-262, 2015
Prediction of intracellular exposure bridges the gap between target-and cell-based drug discovery
A Mateus, LJ Gordon, GJ Wayne, H Almqvist, H Axelsson, ...
Proceedings of the National Academy of Sciences 114 (30), E6231-E6239, 2017
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