Pär Matsson
Pär Matsson
Associate Professor, Department of Pharmacy, Uppsala University
Verified email at farmaci.uu.se
TitleCited byYear
Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs
P Matsson, JM Pedersen, U Norinder, CAS Bergström, P Artursson
Pharmaceutical research 26 (8), 1816-1831, 2009
2532009
Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver
X Chu, K Korzekwa, R Elsby, K Fenner, A Galetin, Y Lai, P Matsson, ...
Clinical Pharmacology & Therapeutics 94 (1), 126-141, 2013
1622013
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1
G Ahlin, J Karlsson, JM Pedersen, L Gustavsson, R Larsson, P Matsson, ...
Journal of medicinal chemistry 51 (19), 5932-5942, 2008
1462008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)
JM Pedersen, P Matsson, CAS Bergström, U Norinder, J Hoogstraate, ...
Journal of medicinal chemistry 51 (11), 3275-3287, 2008
1202008
Exploring the role of different drug transport routes in permeability screening
P Matsson, CAS Bergström, N Nagahara, S Tavelin, U Norinder, ...
Journal of medicinal chemistry 48 (2), 604-613, 2005
1182005
A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2)
P Matsson, G Englund, G Ahlin, CAS Bergström, U Norinder, P Artursson
Journal of Pharmacology and Experimental Therapeutics 323 (1), 19-30, 2007
1142007
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11)
JM Pedersen, P Matsson, CAS Bergström, J Hoogstraate, A Norén, ...
toxicological sciences 136 (2), 328-343, 2013
1072013
Profiling of a prescription drug library for potential renal drug–drug interactions mediated by the organic cation transporter 2
Y Kido, P Matsson, KM Giacomini
Journal of medicinal chemistry 54 (13), 4548-4558, 2011
1072011
Comparison of human solute carriers
A Schlessinger, P Matsson, JE Shima, U Pieper, SW Yee, L Kelly, ...
Protein Science 19 (3), 412-428, 2010
892010
Rapid measurement of intracellular unbound drug concentrations
A Mateus, P Matsson, P Artursson
Molecular pharmaceutics 10 (6), 2467-2478, 2013
822013
Cell permeability beyond the rule of 5
P Matsson, BC Doak, B Over, J Kihlberg
Advanced drug delivery reviews 101, 42-61, 2016
702016
Structural and conformational determinants of macrocycle cell permeability
B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ...
Nature chemical biology 12 (12), 1065, 2016
562016
Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties
B Over, P McCarren, P Artursson, M Foley, F Giordanetto, G Grönberg, ...
Journal of medicinal chemistry 57 (6), 2746-2754, 2014
562014
Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation
SE Hesselson, P Matsson, JE Shima, H Fukushima, SW Yee, ...
PloS one 4 (9), e6942, 2009
342009
Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5
M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ...
Journal of medicinal chemistry 61 (9), 4189-4202, 2018
292018
Pharmacokinetic profiling in drug research: biological, physicochemical, and computational strategies
B Testa, SD Krämer, H Wunderli-Allenspach, G Folkers
Verlag Helvetica Chimica Acta, 2006
292006
Quantifying the impact of transporters on cellular drug permeability
P Matsson, LA Fenu, P Lundquist, JR Wiśniewski, M Kansy, P Artursson
Trends in pharmacological sciences 36 (5), 255-262, 2015
272015
Intracellular drug bioavailability: a new predictor of system dependent drug disposition
A Mateus, A Treyer, C Wegler, M Karlgren, P Matsson, P Artursson
Scientific reports 7, 43047, 2017
242017
The proteome of filter-grown Caco-2 cells with a focus on proteins involved in drug disposition
M Ölander, JR Wiśniewski, P Matsson, P Lundquist, P Artursson
Journal of pharmaceutical sciences 105 (2), 817-827, 2016
242016
Prediction of intracellular exposure bridges the gap between target-and cell-based drug discovery
A Mateus, LJ Gordon, GJ Wayne, H Almqvist, H Axelsson, ...
Proceedings of the National Academy of Sciences 114 (30), E6231-E6239, 2017
232017
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