Jun Wang
Title
Cited by
Cited by
Year
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
SD Cady, K Schmidt-Rohr, J Wang, CS Soto, WF DeGrado, M Hong
Nature 463 (7281), 689-692, 2010
5962010
Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
J Wang, Y Wu, C Ma, G Fiorin, J Wang, LH Pinto, RA Lamb, ML Klein, ...
Proceedings of the National Academy of Sciences 110 (4), 1315-1320, 2013
1882013
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto, X Zhang, ...
Cell research 30 (8), 678-692, 2020
1872020
Protein and small molecule microarrays: powerful tools for high-throughput proteomics
M Uttamchandani, J Wang, SQ Yao
Molecular Biosystems 2 (1), 58-68, 2006
1522006
Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2
J Wang, C Ma, G Fiorin, V Carnevale, T Wang, F Hu, RA Lamb, LH Pinto, ...
Journal of the American Chemical Society 133 (32), 12834-12841, 2011
1302011
Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus
J Wang, JX Qiu, C Soto, WF DeGrado
Current opinion in structural biology 21 (1), 68-80, 2011
1262011
Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus
V Balannik, J Wang, Y Ohigashi, X Jing, E Magavern, RA Lamb, ...
Biochemistry 48 (50), 11872-11882, 2009
1092009
Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission
NW Schmidt, A Mishra, J Wang, WF DeGrado, GCL Wong
Journal of the American Chemical Society 135 (37), 13710-13719, 2013
1062013
Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus
J Wang, SD Cady, V Balannik, LH Pinto, WF DeGrado, M Hong
Journal of the American Chemical Society 131 (23), 8066-8076, 2009
1022009
Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine …
SD Cady, J Wang, Y Wu, WF DeGrado, M Hong
Journal of the American Chemical Society 133 (12), 4274-4284, 2011
1012011
Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus
J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ...
Journal of medicinal chemistry 56 (7), 2804-2812, 2013
972013
Proton and cation transport activity of the M2 proton channel from influenza A virus
T Leiding, J Wang, J Martinsson, WF DeGrado, SP Ĺrsköld
Proceedings of the National Academy of Sciences 107 (35), 15409-15414, 2010
812010
Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus
MD Duque, C Ma, E Torres, J Wang, L Naesens, J Juárez-Jiménez, ...
Journal of medicinal chemistry 54 (8), 2646-2657, 2011
732011
Rapid assembly of matrix metalloprotease inhibitors using click chemistry
J Wang, M Uttamchandani, J Li, M Hu, SQ Yao
Organic letters 8 (17), 3821-3824, 2006
702006
Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 …
Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ...
Journal of the American Chemical Society 136 (52), 17987-17995, 2014
672014
Inhibitor fingerprinting of matrix metalloproteases using a combinatorial peptide hydroxamate library
M Uttamchandani, J Wang, J Li, M Hu, H Sun, KYT Chen, K Liu, SQ Yao
Journal of the American Chemical Society 129 (25), 7848-7858, 2007
632007
Quantitative inhibitor fingerprinting of metalloproteases using small molecule microarrays
M Uttamchandani, WL Lee, J Wang, SQ Yao
Journal of the American Chemical Society 129 (43), 13110-13117, 2007
612007
Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel
J Wang, C Ma, Y Wu, RA Lamb, LH Pinto, WF DeGrado
Journal of the American Chemical Society 133 (35), 13844-13847, 2011
602011
Drug-induced conformational and dynamical changes of the S31N mutant of the influenza M2 proton channel investigated by solid-state NMR
JK Williams, D Tietze, J Wang, Y Wu, WF DeGrado, M Hong
Journal of the American Chemical Society 135 (26), 9885-9897, 2013
592013
Recent developments in microarray-based enzyme assays: from functional annotation to substrate/inhibitor fingerprinting
H Sun, S Chattopadhaya, J Wang, SQ Yao
Analytical and bioanalytical chemistry 386 (3), 416-426, 2006
592006
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