Följ
Sean Halper
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Simultaneous repression of multiple bacterial genes using nonrepetitive extra-long sgRNA arrays
AC Reis, SM Halper, GE Vezeau, DP Cetnar, A Hossain, PR Clauer, ...
Nature biotechnology 37 (11), 1294-1301, 2019
1282019
Automated design of thousands of nonrepetitive parts for engineering stable genetic systems
A Hossain, E Lopez, SM Halper, DP Cetnar, AC Reis, D Strickland, ...
Nature biotechnology 38 (12), 1466-1475, 2020
952020
Synthesis success calculator: predicting the rapid synthesis of DNA fragments with machine learning
SM Halper, A Hossain, HM Salis
ACS Synthetic Biology 9 (7), 1563-1571, 2020
142020
An automated pipeline for engineering many-enzyme pathways: computational sequence design, pathway expression-flux mapping, and scalable pathway optimization
SM Halper, DP Cetnar, HM Salis
Synthetic Metabolic Pathways: Methods and Protocols, 39-61, 2018
92018
Automated Parameterization of Predictive Kinetic Metabolic Models from Sparse Datasets for Efficient Optimization of Many-Enzyme Heterologous Pathways
SM Halper, I Farasat, HM Salis
bioRxiv, 161372, 2017
12017
A modular toolkit for environmental Rhodococcus, Gordonia, and Nocardia enables complex metabolic manipulation.
Z Jansen, A Alameri, Q Wei, DL Kulhanek, AR Gilmour, S Halper, ...
bioRxiv, 2024.02. 21.581484, 2024
2024
Engineered CRISPR/Cas9 Systems for Simultaneous Long-term Regulation of Multiple Targets
H Salis, A Reis, S Halper, P Clauer, GE Vezeau, DP Cetnar, A Hossain
US Patent App. 17/633,321, 2022
2022
Machine Learning-Evolved Biophysical Models for Engineering Genetic Circuits and Pathways
HM Salis, TL LaFleur, A Hossain, AC Reis, SM Halper, GE Vezeau, ...
2022
Development of an Experimental Pipeline for Onboarding of Actinobacteria with Rhodococcus ruber C208 as the Example
N Schwalm III, RL Renberg, C Hellman, M Chu, SM Halper, RM Pullen, ...
2020
Design Optimization Algorithms for Synthetic Biology Applications
S Halper
The Pennsylvania State University, 2019
2019
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Artiklar 1–10