| Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons BJ Wainger, E Kiskinis, C Mellin, O Wiskow, SSW Han, J Sandoe, ... Cell reports 7 (1), 1-11, 2014 | 695 | 2014 |
| Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations NH Alami, RB Smith, MA Carrasco, LA Williams, CS Winborn, SSW Han, ... Neuron 81 (3), 536-543, 2014 | 692 | 2014 |
| Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1 E Kiskinis, J Sandoe, LA Williams, GL Boulting, R Moccia, BJ Wainger, ... Cell stem cell 14 (6), 781-795, 2014 | 501 | 2014 |
| KEEP ON GOING, a RING E3 Ligase Essential for Arabidopsis Growth and Development, Is Involved in Abscisic Acid Signaling SL Stone, LA Williams, LM Farmer, RD Vierstra, J Callis The Plant Cell 18 (12), 3415-3428, 2006 | 424 | 2006 |
| ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ... Nature neuroscience 22 (2), 167-179, 2019 | 410 | 2019 |
| Constructing and deconstructing stem cell models of neurological disease SSW Han, LA Williams, KC Eggan Neuron 70 (4), 626-644, 2011 | 194 | 2011 |
| How to make spinal motor neurons BN Davis-Dusenbery, LA Williams, JR Klim, K Eggan Development 141 (3), 491-501, 2014 | 174 | 2014 |
| Reactive astrocytes promote ALS-like degeneration and intracellular protein aggregation in human motor neurons by disrupting autophagy through TGF-β1 P Tripathi, N Rodriguez-Muela, JR Klim, AS de Boer, S Agrawal, ... Stem cell reports 9 (2), 667-680, 2017 | 134 | 2017 |
| Definition and interactions of a positive regulatory element of the Arabidopsis INNER NO OUTER promoter RJ Meister, LA Williams, MM Monfared, TL Gallagher, EA Kraft, ... The Plant Journal 37 (3), 426-438, 2004 | 114 | 2004 |
| SnapShot: directed differentiation of pluripotent stem cells LA Williams, BN Davis-Dusenbery, KC Eggan Cell 149 (5), 1174-1174. e1, 2012 | 103 | 2012 |
| Notch inhibition allows oncogene-independent generation of iPS cells JK Ichida, J Tcw, LA Williams, AC Carter, Y Shi, MT Moura, M Ziller, ... Nature chemical biology 10 (8), 632-639, 2014 | 75 | 2014 |
| TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons MA Vogt, Z Ehsaei, P Knuckles, A Higginbottom, MS Helmbrecht, ... Scientific reports 8 (1), 8097, 2018 | 54 | 2018 |
| A stem cell-based screening platform identifies compounds that desensitize motor neurons to endoplasmic reticulum stress S Thams, ER Lowry, MH Larraufie, KJ Spiller, H Li, DJ Williams, P Hoang, ... Molecular Therapy 27 (1), 87-101, 2019 | 45 | 2019 |
| Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls D Simkin, V Papakis, BI Bustos, CM Ambrosi, SJ Ryan, V Baru, ... Stem Cell Reports 17 (4), 993-1008, 2022 | 43 | 2022 |
| All‐Optical Electrophysiology for Disease Modeling and Pharmacological Characterization of Neurons CA Werley, T Brookings, H Upadhyay, LA Williams, OB McManus, ... Current protocols in pharmacology 78 (1), 11.20. 1-11.20. 24, 2017 | 35 | 2017 |
| Positive- and negative-acting regulatory elements contribute to the tissue-specific expression of INNER NO OUTER, a YABBY-type transcription factor gene in … MK Simon, LA Williams, K Brady-Passerini, RH Brown, CS Gasser BMC Plant Biology 12, 1-14, 2012 | 21 | 2012 |
| Scalable measurements of intrinsic excitability in human iPS cell-derived excitatory neurons using all-optical electrophysiology LA Williams, V Joshi, M Murphy, J Ferrante, CA Werley, T Brookings, ... Neurochemical research 44, 714-725, 2019 | 14 | 2019 |
| ‘Channeling’therapeutic discovery for epileptic encephalopathy through iPSC technologies D Simkin, C Ambrosi, KA Marshall, LA Williams, J Eisenberg, M Gharib, ... Trends in Pharmacological Sciences 43 (5), 392-405, 2022 | 13 | 2022 |
| Suppression of Kv3. 3 channels by antisense oligonucleotides reverses biochemical effects and motor impairment in spinocerebellar ataxia type 13 mice Y Zhang, IH Quraishi, H McClure, LA Williams, YC Cheng, S Kale, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 6 | 2021 |
| Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models LA Williams, DJ Gerber, A Elder, WC Tseng, V Baru, N Delaney-Busch, ... Molecular Therapy-Nucleic Acids 29, 189-203, 2022 | 4 | 2022 |
