| Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer’s disease: a focused review on recent advances JR Chong, NJ Ashton, TK Karikari, T Tanaka, M Schöll, H Zetterberg, ... Journal of Neurology, Neurosurgery & Psychiatry 92 (11), 1231-1241, 2021 | 62 | 2021 |
| Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration YL Chai, JR Chong, J Weng, D Howlett, A Halsey, JH Lee, J Attems, ... Brain pathology 29 (1), 63-74, 2019 | 60 | 2019 |
| Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment YL Chai, JR Chong, AR Raquib, X Xu, S Hilal, N Venketasubramanian, ... Scientific reports 11 (1), 4010, 2021 | 56 | 2021 |
| APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms A Charidimou, HI Zonneveld, S Shams, K Kantarci, A Shoamanesh, ... Neurology 93 (4), e358-e371, 2019 | 52 | 2019 |
| Novel pathophysiological markers are revealed by iTRAQ-based quantitative clinical proteomics approach in vascular dementia A Datta, J Qian, R Chong, RN Kalaria, P Francis, MKP Lai, CP Chen, ... Journal of proteomics 99, 54-67, 2014 | 43 | 2014 |
| Plasma P‐tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant … JR Chong, NJ Ashton, TK Karikari, T Tanaka, FN Saridin, A Reilhac, ... Alzheimer's & Dementia 17 (10), 1649-1662, 2021 | 42 | 2021 |
| Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia LY Wu, IK Cheah, JR Chong, YL Chai, JY Tan, S Hilal, H Vrooman, ... Free Radical Biology and Medicine 177, 201-211, 2021 | 34 | 2021 |
| Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias H Xing, YA Lim, JR Chong, JH Lee, D Aarsland, CG Ballard, PT Francis, ... Molecular brain 9, 1-12, 2016 | 31 | 2016 |
| Mitochondrial translocase of the outer membrane alterations may underlie dysfunctional oxidative phosphorylation in Alzheimer’s disease YL Chai, H Xing, JR Chong, PT Francis, CG Ballard, CP Chen, MKP Lai Journal of Alzheimer's Disease 61 (2), 793-801, 2018 | 28 | 2018 |
| Increased transforming growth factor β2 in the neocortex of Alzheimer’s disease and dementia with lewy bodies is correlated with disease severity and soluble Aβ 42 load JR Chong, YL Chai, JH Lee, D Howlett, J Attems, CG Ballard, D Aarsland, ... Journal of Alzheimer's Disease 56 (1), 157-166, 2017 | 27 | 2017 |
| Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer’s disease and vascular cognitive impairment XY Chua, YL Chai, WS Chew, JR Chong, HL Ang, P Xiang, K Camara, ... Alzheimer's Research & Therapy 12, 1-12, 2020 | 22 | 2020 |
| Low plasma ergothioneine predicts cognitive and functional decline in an elderly cohort attending memory clinics LY Wu, CN Kan, IK Cheah, JR Chong, X Xu, H Vrooman, S Hilal, ... Antioxidants 11 (9), 1717, 2022 | 19 | 2022 |
| Head‐to‐head comparison of amplified plasmonic exosome Aβ42 platform and single‐molecule array immunoassay in a memory clinic cohort T Tanaka, JC Ruifen, YH Nai, CH Tan, CZJ Lim, Y Zhang, ... European journal of neurology 28 (5), 1479-1489, 2021 | 14 | 2021 |
| Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with … JR Chong, S Hilal, NJ Ashton, TK Karikari, A Reilhac, H Vrooman, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 15 (1 …, 2023 | 12 | 2023 |
| Elevation of inactive cleaved annexin A1 in the neocortex is associated with amyloid, inflammatory and apoptotic markers in neurodegenerative dementias XY Chua, JR Chong, AL Cheng, JH Lee, C Ballard, D Aarsland, ... Neurochemistry International 152, 105251, 2022 | 11 | 2022 |
| Sphingolipidomics analysis of large clinical cohorts. Part 1: technical notes and practical considerations WS Chew, WL Seow, JR Chong, MKP Lai, F Torta, MR Wenk, DR Herr Biochemical and biophysical research communications 504 (3), 596-601, 2018 | 11 | 2018 |
| Sphingolipidomics analysis of large clinical cohorts. Part 2: Potential impact and applications JR Chong, P Xiang, W Wang, T Hind, WS Chew, WY Ong, MKP Lai, ... Biochemical and biophysical research communications 504 (3), 602-607, 2018 | 11 | 2018 |
| Clinical trials in dementia with Lewy bodies: the evolving concept of co-pathologies, patient selection and biomarkers LL Gibson, C Abdelnour, J Chong, C Ballard, D Aarsland Current Opinion in Neurology 36 (4), 264-275, 2023 | 6 | 2023 |
| Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer’s disease but not Lewy body dementias YL Chai, JH Lee, JR Chong, C Ballard, PT Francis, BK Kennedy, ... Journal of Neuroinflammation 20 (1), 111, 2023 | 6 | 2023 |
| Elevated soluble tnf-receptor 1 in the serum of predementia subjects with cerebral small vessel disease KHT Salai, LY Wu, JR Chong, YL Chai, B Gyanwali, C Robert, S Hilal, ... Biomolecules 13 (3), 525, 2023 | 4 | 2023 |
Christopher ChenAssociate Professor, Department of Pharmacology, National University of SingaporeVerified email at nus.edu.sg
