andre Nussenzweig
andre Nussenzweig
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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
SF Bunting, E CallÚn, N Wong, HT Chen, F Polato, A Gunn, A Bothmer, ...
Cell 141 (2), 243-254, 2010
Genomic instability in mice lacking histone H2AX
A Celeste, S Petersen, PJ Romanienko, O Fernandez-Capetillo, HT Chen, ...
Science 296 (5569), 922-927, 2002
The multifaceted roles of PARP1 in DNA repair and chromatin remodelling
A Ray Chaudhuri, A Nussenzweig
Nature reviews Molecular cell biology 18 (10), 610-621, 2017
H2AX: the histone guardian of the genome
O Fernandez-Capetillo, A Lee, M Nussenzweig, A Nussenzweig
DNA repair 3 (8-9), 959-967, 2004
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
DJ Rossi, D Bryder, J Seita, A Nussenzweig, J Hoeijmakers, IL Weissman
Nature 447 (7145), 725-729, 2007
Endogenous DNA damage as a source of genomic instability in cancer
A Tubbs, A Nussenzweig
Cell 168 (4), 644-656, 2017
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
A Celeste, O Fernandez-Capetillo, MJ Kruhlak, DR Pilch, DW Staudt, ...
Nature cell biology 5 (7), 675-679, 2003
DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1
O Fernandez-Capetillo, HT Chen, A Celeste, I Ward, PJ Romanienko, ...
Nature cell biology 4 (12), 993-997, 2002
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
Z Lou, K Minter-Dykhouse, S Franco, M Gostissa, MA Rivera, A Celeste, ...
Molecular cell 21 (2), 187-200, 2006
Replication fork stability confers chemoresistance in BRCA-deficient cells
A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ...
Nature 535 (7612), 382-387, 2016
Requirement for Ku80 in growth and immunoglobulin V (D) J recombination
A Nussenzweig, C Chen, V da Costa Soares, M Sanchez, K Sokol, ...
Nature 382 (6591), 551-555, 1996
DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
MJ Difilippantonio, J Zhu, HT Chen, E Meffre, MC Nussenzweig, EE Max, ...
Nature 404 (6777), 510-514, 2000
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility
A Celeste, S Difilippantonio, MJ Difilippantonio, O Fernandez-Capetillo, ...
Cell 114 (3), 371-383, 2003
H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis
O Fernandez-Capetillo, SK Mahadevaiah, A Celeste, PJ Romanienko, ...
Developmental cell 4 (4), 497-508, 2003
Silencing of unsynapsed meiotic chromosomes in the mouse
JMA Turner, SK Mahadevaiah, O Fernandez-Capetillo, A Nussenzweig, ...
Nature genetics 37 (1), 41-47, 2005
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
MJ Kruhlak, A Celeste, G Dellaire, O Fernandez-Capetillo, WG Müller, ...
The Journal of cell biology 172 (6), 823-834, 2006
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
S Petersen, R Casellas, B Reina-San-Martin, HT Chen, MJ Difilippantonio, ...
Nature 414 (6864), 660-665, 2001
AID is required for c-myc/IgH chromosome translocations in vivo
AR Ramiro, M Jankovic, T Eisenreich, S Difilippantonio, S Chen-Kiang, ...
Cell 118 (4), 431-438, 2004
Characteristics of γ-H2AX foci at DNA double-strand breaks sites
DR Pilch, OA Sedelnikova, C Redon, A Celeste, A Nussenzweig, ...
Biochemistry and cell biology 81 (3), 123-129, 2003
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase Iá…
T Furuta, H Takemura, ZY Liao, GJ Aune, C Redon, OA Sedelnikova, ...
Journal of Biological Chemistry 278 (22), 20303-20312, 2003
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