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Helen Walden
Helen Walden
Verified email at glasgow.ac.uk
Title
Cited by
Cited by
Year
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open biology 2 (5), 120080, 2012
9082012
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases
M Zhuang, MF Calabrese, J Liu, MB Waddell, A Nourse, M Hammel, ...
Molecular cell 36 (1), 39-50, 2009
4702009
Types of ubiquitin ligases
FE Morreale, H Walden
Cell 165 (1), 248-248. e1, 2016
4012016
Autoregulation of Parkin activity through its ubiquitin‐like domain
VK Chaugule, L Burchell, KR Barber, A Sidhu, SJ Leslie, GS Shaw, ...
The EMBO journal 30 (14), 2853-2867, 2011
3592011
Ubiquitin signalling in DNA replication and repair
HD Ulrich, H Walden
Nature reviews Molecular cell biology 11 (7), 479-489, 2010
3342010
RBR E3 ubiquitin ligases: new structures, new insights, new questions
DE Spratt, H Walden, GS Shaw
Biochemical journal 458 (3), 421-437, 2014
3252014
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1
H Walden, MS Podgorski, DT Huang, DW Miller, RJ Howard, DL Minor, ...
Molecular cell 12 (6), 1427-1437, 2003
2972003
The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder
H Walden, AJ Deans
Annual review of biophysics 43, 257-278, 2014
2652014
Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8
H Walden, MS Podgorski, BA Schulman
Nature 422 (6929), 330-334, 2003
2512003
Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability
KE Marshall, KL Morris, D Charlton, N O’Reilly, L Lewis, H Walden, ...
Biochemistry 50 (12), 2061-2071, 2011
2412011
Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK 1‐dependent phosphorylation and activation
A Kazlauskaite, RJ Martínez‐Torres, S Wilkie, A Kumar, J Peltier, ...
EMBO reports 16 (8), 939-954, 2015
2242015
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis
A Kumar, JD Aguirre, TEC Condos, RJ Martinez‐Torres, VK Chaugule, ...
The EMBO journal 34 (20), 2506-2521, 2015
1812015
Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
SJ Turner, K Kedzierska, H Komodromou, NL La Gruta, MA Dunstone, ...
Nature immunology 6 (4), 382-389, 2005
1762005
Tiny TIM: a small, tetrameric, hyperthermostable triosephosphate isomerase
H Walden, GS Bell, RJM Russell, B Siebers, R Hensel, GL Taylor
Journal of molecular biology 306 (4), 745-757, 2001
1622001
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
DE Spratt, R Julio Martinez-Torres, YJ Noh, P Mercier, N Manczyk, ...
Nature communications 4 (1), 1983, 2013
1372013
RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns
H Walden, K Rittinger
Nature structural & molecular biology 25 (6), 440-445, 2018
1292018
Ubiquitin-like protein activation
DT Huang, H Walden, D Duda, BA Schulman
Oncogene 23 (11), 1958-1971, 2004
1162004
The CCP4 suite: integrative software for macromolecular crystallography
J Agirre, M Atanasova, H Bagdonas, CB Ballard, A Baslé, ...
Acta Crystallographica Section D: Structural Biology 79 (6), 449-461, 2023
1152023
Selenium incorporation using recombinant techniques
H Walden
Acta Crystallographica Section D: Biological Crystallography 66 (4), 352-357, 2010
1122010
Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity
A Kumar, VK Chaugule, TEC Condos, KR Barber, C Johnson, R Toth, ...
Nature structural & molecular biology 24 (5), 475-483, 2017
1002017
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