Helen Walden
Helen Walden
Verified email at glasgow.ac.uk
Title
Cited by
Cited by
Year
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open biology 2 (5), 120080, 2012
6022012
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases
M Zhuang, MF Calabrese, J Liu, MB Waddell, A Nourse, M Hammel, ...
Molecular cell 36 (1), 39-50, 2009
3172009
Autoregulation of Parkin activity through its ubiquitin‐like domain
VK Chaugule, L Burchell, KR Barber, A Sidhu, SJ Leslie, GS Shaw, ...
The EMBO journal 30 (14), 2853-2867, 2011
2782011
Ubiquitin signalling in DNA replication and repair
HD Ulrich, H Walden
Nature reviews Molecular cell biology 11 (7), 479-489, 2010
2762010
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1
H Walden, MS Podgorski, DT Huang, DW Miller, RJ Howard, DL Minor Jr, ...
Molecular cell 12 (6), 1427-1437, 2003
2412003
Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8
H Walden, MS Podgorski, BA Schulman
Nature 422 (6929), 330-334, 2003
2242003
RBR E3 ubiquitin ligases: new structures, new insights, new questions
DE Spratt, H Walden, GS Shaw
Biochemical journal 458 (3), 421-437, 2014
2172014
The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder
H Walden, AJ Deans
Annual review of biophysics 43, 257-278, 2014
2112014
Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability
KE Marshall, KL Morris, D Charlton, N O’Reilly, L Lewis, H Walden, ...
Biochemistry 50 (12), 2061-2071, 2011
1902011
Types of ubiquitin ligases
FE Morreale, H Walden
Cell 165 (1), 248-248. e1, 2016
1652016
Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
SJ Turner, K Kedzierska, H Komodromou, NL La Gruta, MA Dunstone, ...
Nature immunology 6 (4), 382-389, 2005
1572005
Tiny TIM: a small, tetrameric, hyperthermostable triosephosphate isomerase
H Walden, GS Bell, RJM Russell, B Siebers, R Hensel, GL Taylor
Journal of molecular biology 306 (4), 745-757, 2001
1462001
Binding to serine 65‐phosphorylated ubiquitin primes Parkin for optimal PINK 1‐dependent phosphorylation and activation
A Kazlauskaite, RJ Martínez‐Torres, S Wilkie, A Kumar, J Peltier, ...
EMBO reports 16 (8), 939-954, 2015
1372015
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis
A Kumar, JD Aguirre, TEC Condos, RJ Martinez‐Torres, VK Chaugule, ...
The EMBO journal 34 (20), 2506-2521, 2015
1232015
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
DE Spratt, RJ Martinez-Torres, YJ Noh, P Mercier, N Manczyk, KR Barber, ...
Nature communications 4 (1), 1-12, 2013
1082013
Ubiquitin-like protein activation
DT Huang, H Walden, D Duda, BA Schulman
Oncogene 23 (11), 1958-1971, 2004
1012004
The structure of the catalytic subunit FANCL of the Fanconi anemia core complex
AR Cole, LPC Lewis, H Walden
Nature structural & molecular biology 17 (3), 294-298, 2010
842010
Selenium incorporation using recombinant techniques
H Walden
Acta Crystallographica Section D: Biological Crystallography 66 (4), 352-357, 2010
822010
The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus
A Theodossis, H Walden, EJ Westwick, H Connaris, HJ Lamble, ...
Journal of Biological Chemistry 279 (42), 43886-43892, 2004
812004
Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection
C Hodson, A Purkiss, JA Miles, H Walden
Structure 22 (2), 337-344, 2014
712014
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Articles 1–20