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Sergi Regot
Sergi Regot
Assistant Professor at Johns Hopkins School of Medicine
Verifierad e-postadress på jhmi.edu - Startsida
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Temporal control of mammalian cortical neurogenesis by m6A methylation
KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass, D Jimenez-Cyrus, ...
Cell 171 (4), 877-889. e17, 2017
6352017
High-sensitivity measurements of multiple kinase activities in live single cells
S Regot, JJ Hughey, BT Bajar, S Carrasco, MW Covert
Cell 157 (7), 1724-1734, 2014
5422014
Distributed biological computation with multicellular engineered networks
S Regot, J Macia, N Conde, K Furukawa, J Kjellén, T Peeters, S Hohmann, ...
Nature 469 (7329), 207-211, 2011
4202011
Ribosome collisions trigger general stress responses to regulate cell fate
CCC Wu, A Peterson, B Zinshteyn, S Regot, R Green
Cell 182 (2), 404-416. e14, 2020
2952020
Dynamic signaling in the Hog1 MAPK pathway relies on high basal signal transduction
J Macia, S Regot, T Peeters, N Conde, R Solé, F Posas
Science signaling 2 (63), ra13-ra13, 2009
1662009
A real-time biosensor for ERK activity reveals signaling dynamics during C. elegans cell fate specification
C De la Cova, R Townley, S Regot, I Greenwald
Developmental cell 42 (5), 542-553. e4, 2017
1402017
The HOG pathway dictates the short-term translational response after hyperosmotic shock
J Warringer, M Hult, S Regot, F Posas, P Sunnerhagen
Molecular biology of the cell 21 (17), 3080-3092, 2010
1052010
Live-cell measurements of kinase activity in single cells using translocation reporters
T Kudo, S Jeknić, DN Macklin, S Akhter, JJ Hughey, S Regot, MW Covert
Nature protocols 13 (1), 155-169, 2018
1042018
Accelerated discovery via a whole-cell model
JC Sanghvi, S Regot, S Carrasco, JR Karr, MV Gutschow, B Bolival Jr, ...
Nature methods 10 (12), 1192-1195, 2013
802013
Cell-cycle-dependent ERK signaling dynamics direct fate specification in the mammalian preimplantation embryo
MJ Pokrass, KA Ryan, T Xin, B Pielstick, W Timp, V Greco, S Regot
Developmental Cell 55 (3), 328-340. e5, 2020
662020
MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression
TJ Aikin, AF Peterson, MJ Pokrass, HR Clark, S Regot
Elife 9, e60541, 2020
572020
Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation
HW Yang, SD Cappell, A Jaimovich, C Liu, M Chung, LH Daigh, LR Pack, ...
Elife 9, e44571, 2020
532020
NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop
MM DeFelice, HR Clark, JJ Hughey, I Maayan, T Kudo, MV Gutschow, ...
Science signaling 12 (579), eaau3568, 2019
532019
The Hog1 stress-activated protein kinase targets nucleoporins to control mRNA export upon stress
S Regot, E De Nadal, S Rodríguez-Navarro, A González-Novo, ...
Journal of Biological Chemistry 288 (24), 17384-17398, 2013
442013
Parallel feedback loops control the basal activity of the HOG MAPK signaling cascade
H Sharifian, F Lampert, K Stojanovski, S Regot, S Vaga, R Buser, SS Lee, ...
Integrative biology 7 (4), 412-422, 2015
302015
CaMKII oxidation is a critical performance/disease trade-off acquired at the dawn of vertebrate evolution
Q Wang, EO Hernández-Ochoa, MC Viswanathan, ID Blum, DC Do, ...
Nature communications 12 (1), 3175, 2021
212021
Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
HR Clark, C McKenney, NM Livingston, A Gershman, S Sajjan, IS Chan, ...
Nature communications 12 (1), 1836, 2021
152021
Systematic analysis of the MAPK signaling network reveals MAP3K-driven control of cell fate
AF Peterson, K Ingram, EJ Huang, J Parksong, C McKenney, GS Bever, ...
Cell systems 13 (11), 885-894. e4, 2022
92022
Collective MAPK signaling dynamics coordinates epithelial homeostasis
TJ Aikin, AF Peterson, MJ Pokrass, HR Clark, S Regot
BioRxiv, 826917, 2019
92019
3D time-lapse microscopy paired with endpoint lineage analysis in mouse blastocysts
MJ Pokrass, S Regot
STAR protocols 2 (2), 100446, 2021
32021
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Artiklar 1–20