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Johannes Westman
Johannes Westman
The Hospital for Sick Children, Toronto, Canada
Verifierad e-postadress på sickkids.ca - Startsida
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The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
L Kasper, A König, PA Koenig, MS Gresnigt, J Westman, RA Drummond, ...
Nature communications 9 (1), 4260, 2018
2022018
Phagocytosis of necrotic debris at sites of injury and inflammation
J Westman, S Grinstein, PE Marques
Frontiers in immunology 10, 504868, 2020
1572020
Neutrophil extracellular trap-microparticle complexes enhance thrombin generation via the intrinsic pathway of coagulation in mice
Y Wang, L Luo, OÖ Braun, J Westman, R Madhi, H Herwald, M Mörgelin, ...
Scientific reports 8 (1), 4020, 2018
1392018
Candida albicans hyphal expansion causes phagosomal membrane damage and luminal alkalinization
J Westman, G Moran, S Mogavero, B Hube, S Grinstein
MBio 9 (5), 10.1128/mbio. 01226-18, 2018
882018
Lysosome fusion maintains phagosome integrity during fungal infection
J Westman, GFW Walpole, L Kasper, BY Xue, O Elshafee, B Hube, ...
Cell Host & Microbe 28 (6), 798-812. e6, 2020
622020
Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo
J Westman, P Papareddy, MW Dahlgren, B Chakrakodi, ...
PLoS pathogens 11 (12), e1005319, 2015
582015
The role of lipids in host–pathogen interactions
GFW Walpole, S Grinstein, J Westman
IUBMB life 70 (5), 384-392, 2018
572018
A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes
S Oehmcke, J Westman, J Malmström, M Mörgelin, AI Olin, B Kreikemeyer, ...
PLoS pathogens 9 (8), e1003529, 2013
492013
I want to break free–macrophage strategies to recognize and kill Candida albicans, and fungal counter-strategies to escape
S Austermeier, L Kasper, J Westman, MS Gresnigt
Current opinion in microbiology 58, 15-23, 2020
392020
Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
J Westman, J Plumb, A Licht, M Yang, S Allert, JR Naglik, B Hube, ...
Cell reports 38 (1), 2022
332022
Determinants of phagosomal pH during host-pathogen interactions
J Westman, S Grinstein
Frontiers in cell and developmental biology 8, 624958, 2021
332021
Integrity under stress: Host membrane remodelling and damage by fungal pathogens
J Westman, B Hube, GD Fairn
Cellular microbiology 21 (4), e13016, 2019
332019
Revisiting the role of calcium in phagosome formation and maturation
J Westman, S Grinstein, ME Maxson
Journal of Leukocyte Biology 106 (4), 837-851, 2019
272019
Treatment with p33 curtails morbidity and mortality in a histone-induced murine shock model
J Westman, E Smeds, L Johansson, M Mörgelin, AI Olin, E Malmström, ...
Journal of innate immunity 6 (6), 819-830, 2014
242014
Candida albicans hyphal expansion causes phagosomal membrane damage and luminal alkalinization. mBio 9: e01226-18
J Westman, G Moran, S Mogavero, B Hube, S Grinstein, MS Swanson
222018
p33 (gC1q receptor) prevents cell damage by blocking the cytolytic activity of antimicrobial peptides
J Westman, FC Hansen, AI Olin, M Mörgelin, A Schmidtchen, H Herwald
The Journal of Immunology 191 (11), 5714-5721, 2013
222013
A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection
P Papareddy, M Rossnagel, F Doreen Hollwedel, G Kilic, S Veerla, ...
Nature microbiology 4 (12), 2442-2455, 2019
202019
Human endogenous peptide p33 inhibits detrimental effects of LL‐37 on osteoblast viability
D Svensson, J Westman, C Wickström, D Jönsson, H Herwald, ...
Journal of Periodontal Research 50 (1), 80-88, 2015
192015
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes. Nat Commun 9: 4260
L Kasper, A König, PA Koenig, MS Gresnigt, J Westman, RA Drummond, ...
182018
Protein SIC Secreted from Streptococcus pyogenes Forms Complexes with Extracellular Histones That Boost Cytokine Production
J Westman, B Chakrakodi, J Snäll, M Mörgelin, M Bruun Madsen, ...
Frontiers in immunology 9, 236, 2018
172018
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Artiklar 1–20