Maximilian Larena
Maximilian Larena
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Genomic insights into population history and biological adaptation in Oceania
J Choin, J Mendoza-Revilla, LR Arauna, S Cuadros-Espinoza, O Cassar, ...
Nature 592 (7855), 583-589, 2021
Pivotal Role of Antibody and Subsidiary Contribution of CD8+ T Cells to Recovery from Infection in a Murine Model of Japanese Encephalitis
M Larena, M Regner, E Lee, M Lobigs
Journal of virology 85 (11), 5446-5455, 2011
An inactivated cell culture Japanese encephalitis vaccine (JE-ADVAX) formulated with delta inulin adjuvant provides robust heterologous protection against West Nile …
N Petrovsky, M Larena, V Siddharthan, NA Prow, RA Hall, M Lobigs, ...
Journal of virology 87 (18), 10324-10333, 2013
Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP–protein kinase A and inflammasome-dependent IL-1 signaling
M Larena, J Holmgren, M Lebens, M Terrinoni, A Lundgren
The Journal of Immunology 194 (8), 3829-3839, 2015
JE-ADVAX Vaccine Protection against Japanese Encephalitis Virus Mediated by Memory B Cells in the Absence of CD8+ T Cells and Pre-Exposure Neutralizing …
M Larena, NA Prow, RA Hall, N Petrovsky, M Lobigs
Journal of virology 87 (8), 4395-4402, 2013
Cytolytic effector pathways and IFN‐γ help protect against J apanese encephalitis
M Larena, M Regner, M Lobigs
European journal of immunology 43 (7), 1789-1798, 2013
Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus
M Lobigs, M Larena, M Alsharifi, E Lee, M Pavy
Journal of virology 83 (6), 2436-2445, 2009
Multiple migrations to the Philippines during the last 50,000 years
M Larena, F Sanchez-Quinto, P Sjödin, J McKenna, C Ebeo, R Reyes, ...
Proceedings of the National Academy of Sciences 118 (13), e2026132118, 2021
Philippine Ayta possess the highest level of Denisovan ancestry in the world
M Larena, J McKenna, F Sanchez-Quinto, C Bernhardsson, C Ebeo, ...
Current Biology 31 (19), 4219-4230. e10, 2021
Construction and preclinical evaluation of mmCT, a novel mutant cholera toxin adjuvant that can be efficiently produced in genetically manipulated Vibrio cholerae
M Lebens, M Terrinoni, SL Karlsson, M Larena, T Gustafsson-Hedberg, ...
Vaccine 34 (18), 2121-2128, 2016
The chemokine receptor CCR5, a therapeutic target for HIV/AIDS antagonists, is critical for recovery in a mouse model of Japanese encephalitis
M Larena, M Regner, M Lobigs
Public Library of Science 7 (9), e44834, 2012
Deficiency in calcium-binding protein S100A4 impairs the adjuvant action of cholera toxin
JB Sun, J Holmgren, M Larena, M Terrinoni, Y Fang, AR Bresnick, Z Xiang
Frontiers in immunology 8, 1119, 2017
Proteomic analysis of cholera toxin adjuvant-stimulated human monocytes identifies Thrombospondin-1 and Integrin-β1 as strongly upregulated molecules involved in adjuvant activity
M Terrinoni, J Holmgren, M Lebens, M Larena
Scientific reports 9 (1), 2812, 2019
Requirement for cyclic AMP/protein kinase A-dependent canonical NFκB signaling in the adjuvant action of cholera toxin and its non-toxic derivative mmCT
M Terrinoni, J Holmgren, M Lebens, M Larena
Frontiers in Immunology 10, 269, 2019
Unveiling the Genetic History of the Maniq, a primary hunter-gatherer society
T Göllner, M Larena, W Kutanan, H Lukas, M Fieder, H Schaschl
Genome Biology and Evolution 14 (4), evac021, 2022
Episodes of diversification and isolation in Island Southeast Asian and Near Oceanian male lineages
M Karmin, R Flores, L Saag, G Hudjashov, N Brucato, ...
Molecular biology and evolution 39 (3), msac045, 2022
Immunobiology of Japanese encephalitis virus
M Larena, M Lobigs
Flavivirus Encephalitis 317, 338, 2011
Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties
M Frese, E Lee, M Larena, PS Lim, S Rao, KI Matthaei, A Khromykh, ...
Journal of Virology 88 (4), 2056-2070, 2014
Demographic history and genetic structure in pre-Hispanic Central Mexico
V Villa-Islas, A Izarraras-Gomez, M Larena, EMP Campos, ...
Science 380 (6645), eadd6142, 2023
Archaic humans have contributed to large-scale variation in modern human T cell receptor genes
M Corcoran, M Chernyshev, M Mandolesi, S Narang, M Kaduk, K Ye, ...
Immunity 56 (3), 635-652. e6, 2023
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