Lars Nilsson
Lars Nilsson
Professor of Pharmacology, University of Oslo
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Translation of the Alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-untranslated region sequences
JT Rogers, LM Leiter, J McPhee, CM Cahill, SS Zhan, H Potter, ...
Journal of Biological Chemistry 274 (10), 6421-6431, 1999
The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice
A Lord, H Kalimo, C Eckman, XQ Zhang, L Lannfelt, LNG Nilsson
Neurobiology of aging 27 (1), 67-77, 2006
Sensitive ELISA detection of amyloid‐β protofibrils in biological samples
H Englund, D Sehlin, AS Johansson, LNG Nilsson, P Gellerfors, S Paulie, ...
Journal of neurochemistry 103 (1), 334-345, 2007
Imaging distinct conformational states of amyloid-β fibrils in Alzheimer’s disease using novel luminescent probes
KPR Nilsson, A Åslund, I Berg, S Nyström, P Konradsson, A Herland, ...
ACS chemical biology 2 (8), 553-560, 2007
α-1-Antichymotrypsin promotes β-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease
LNG Nilsson, KR Bales, G DiCarlo, MN Gordon, D Morgan, SM Paul, ...
Journal of Neuroscience 21 (5), 1444-1451, 2001
Loss of astrocyte polarization in the tg-ArcSwe mouse model of Alzheimer's disease
J Yang, LK Lunde, P Nuntagij, T Oguchi, L Camassa, LNG Nilsson, ...
Journal of Alzheimer's Disease 27 (4), 711-722, 2011
The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation
H Potter, IM Wefes, LNG Nilsson
Neurobiology of aging 22 (6), 923-930, 2001
Animal models of amyloid‐β‐related pathologies in Alzheimer’s disease
O Philipson, A Lord, A Gumucio, P O’Callaghan, L Lannfelt, LNG Nilsson
The FEBS journal 277 (6), 1389-1409, 2010
Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation
LNG Nilsson, GW Arendash, RE Leighty, DA Costa, MA Low, MF Garcia, ...
Neurobiology of aging 25 (9), 1153-1167, 2004
Amyloid‐β oligomers are inefficiently measured by enzyme‐linked immunosorbent assay
C Stenh, H Englund, A Lord, AS Johansson, CG Almeida, P Gellerfors, ...
Annals of neurology 58 (1), 147-150, 2005
A highly insoluble state of Aβ similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice
O Philipson, P Hammarström, KPR Nilsson, E Portelius, T Olofsson, ...
Neurobiology of aging 30 (9), 1393-1405, 2009
Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease
K Henjum, IS Almdahl, V Årskog, L Minthon, O Hansson, T Fladby, ...
Alzheimer's research & therapy 8 (1), 1-11, 2016
Glial activation and inflammation along the Alzheimer’s disease continuum
K Nordengen, BE Kirsebom, K Henjum, P Selnes, B Gísladóttir, ...
Journal of neuroinflammation 16 (1), 1-13, 2019
Amyloid‐β protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice
A Lord, H Englund, L Söderberg, S Tucker, F Clausen, L Hillered, ...
The FEBS journal 276 (4), 995-1006, 2009
Heparan sulfate accumulation with Aβ deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells
P O'Callaghan, E Sandwall, JP Li, H Yu, R Ravid, ZZ Guan, ...
Brain pathology 18 (4), 548-561, 2008
An amyloid-β protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease
A Lord, A Gumucio, H Englund, D Sehlin, VS Sundquist, L Söderberg, ...
Neurobiology of disease 36 (3), 425-434, 2009
The Arctic Alzheimer mutation favors intracellular amyloid‐β production by making amyloid precursor protein less available to α‐secretase
C Sahlin, A Lord, K Magnusson, H Englund, CG Almeida, P Greengard, ...
Journal of neurochemistry 101 (3), 854-862, 2007
Docosahexaenoic acid stimulates non‐amyloidogenic APP processing resulting in reduced Aβ levels in cellular models of Alzheimer's disease
C Sahlin, FE Pettersson, LNG Nilsson, L Lannfelt, AS Johansson
European Journal of Neuroscience 26 (4), 882-889, 2007
The Alzheimer’s disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway
C Jendresen, V Årskog, MR Daws, LNG Nilsson
Journal of neuroinflammation 14 (1), 1-13, 2017
Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
X Zhang, B Wang, P O’Callaghan, E Hjertström, J Jia, F Gong, E Zcharia, ...
Acta neuropathologica 124 (4), 465-478, 2012
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