Whole genome analysis of a schistosomiasis-transmitting freshwater snail CM Adema, LDW Hillier, CS Jones, ES Loker, M Knight, P Minx, ... Nature communications 8 (1), 15451, 2017 | 257 | 2017 |
Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses JM Fitzpatrick, E Peak, S Perally, IW Chalmers, J Barrett, TP Yoshino, ... PLoS neglected tropical diseases 3 (11), e543, 2009 | 150 | 2009 |
Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene … IW Chalmers, AJ McArdle, RMR Coulson, MA Wagner, R Schmid, H Hirai, ... BMC genomics 9, 1-20, 2008 | 146 | 2008 |
Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni KK Geyer, CM Rodríguez López, IW Chalmers, SE Munshi, M Truscott, ... Nature communications 2 (1), 424, 2011 | 120 | 2011 |
Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability E Peak, IW Chalmers, KF Hoffmann PLoS neglected tropical diseases 4 (7), e759, 2010 | 115 | 2010 |
Molecular characterization of omega-1: A hepatotoxic ribonuclease from Schistosoma mansonieggs CM Fitzsimmons, G Schramm, FM Jones, IW Chalmers, KF Hoffmann, ... Molecular & Biochemical Parasitology 144 (1), 123-127, 2005 | 104 | 2005 |
The Schistosoma mansoni Tegumental-Allergen-Like (TAL) Protein Family: Influence of Developmental Expression on Human IgE Responses CM Fitzsimmons, FM Jones, A Stearn, IW Chalmers, KF Hoffmann, ... PLoS neglected tropical diseases 6 (4), e1593, 2012 | 78 | 2012 |
The scandalous failure of scientists to cumulate scientifically I Chalmers Abstract to paper presented at: Ninth World Congress on Health Information …, 2005 | 60 | 2005 |
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions … KK Geyer, UH Niazi, D Duval, C Cosseau, C Tomlinson, IW Chalmers, ... PLoS neglected tropical diseases 11 (5), e0005246, 2017 | 56 | 2017 |
Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum IW Chalmers, KF Hoffmann Parasitology 139 (10), 1231-1245, 2012 | 55 | 2012 |
Excreted/secreted Schistosoma mansoni venom allergen-like 9 (SmVAL9) modulates host extracellular matrix remodelling gene expression TP Yoshino, M Brown, XJ Wu, CJ Jackson, R Ocadiz-Ruiz, IW Chalmers, ... International journal for parasitology 44 (8), 551-563, 2014 | 50 | 2014 |
Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes KK Geyer, IW Chalmers, N MacKintosh, JE Hirst, R Geoghegan, M Badets, ... BMC genomics 14, 1-13, 2013 | 45 | 2013 |
Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni G Padalino, S Ferla, A Brancale, IW Chalmers, KF Hoffmann International Journal for Parasitology: Drugs and Drug Resistance 8 (3), 559-570, 2018 | 42 | 2018 |
Drug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7 N Reimers, A Homann, B Höschler, K Langhans, RA Wilson, C Pierrot, ... PLOS Neglected Tropical Diseases 9 (3), e0003593, 2015 | 32 | 2015 |
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets KCL Whatley, G Padalino, H Whiteland, KK Geyer, BJ Hulme, ... PLoS Neglected Tropical Diseases 13 (11), e0007693, 2019 | 30 | 2019 |
Switching from originator to biosimilar infliximab in paediatric inflammatory bowel disease is feasible and uneventful L Gervais, LL McLean, ML Wilson, C Cameron, L Curtis, V Garrick, ... Journal of pediatric gastroenterology and nutrition 67 (6), 745-748, 2018 | 29 | 2018 |
Schistosoma mansoni schistosomula antigens induce Th1/Pro‐inflammatory cytokine responses M Egesa, L Lubyayi, EM Tukahebwa, BS Bagaya, IW Chalmers, S Wilson, ... Parasite immunology 40 (12), e12592, 2018 | 29 | 2018 |
Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection EJ Farnell, N Tyagi, S Ryan, IW Chalmers, A Pinot de Moira, FM Jones, ... Frontiers in immunology 6, 26, 2015 | 26 | 2015 |
Comparison of porcine airway and intestinal epithelial cell lines for the susceptibility and expression of pattern recognition receptors upon influenza virus infection M Thomas, M Pierson, T Uprety, L Zhu, Z Ran, CC Sreenivasan, D Wang, ... Viruses 10 (6), 312, 2018 | 20 | 2018 |
Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment IW Chalmers, CM Fitzsimmons, M Brown, C Pierrot, FM Jones, ... PLoS neglected tropical diseases 9 (7), e0003920, 2015 | 19 | 2015 |