Brigitt Raux
Brigitt Raux
Postdoctoral Researcher, Bordeaux University, Interdisciplinary Institute of Neuroscience
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Exploring selective inhibition of the first bromodomain of the human bromodomain and extra-terminal domain (BET) proteins
B Raux, Y Voitovich, C Derviaux, A Lugari, E Rebuffet, S Milhas, S Priet, ...
Journal of medicinal chemistry 59 (4), 1634-1641, 2016
Integrated strategy for lead optimization based on fragment growing: the diversity-oriented-target-focused-synthesis approach
L Hoffer, YV Voitovich, B Raux, K Carrasco, C Muller, AY Fedorov, ...
Journal of medicinal chemistry 61 (13), 5719-5732, 2018
Protein–Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery
S Milhas, B Raux, S Betzi, C Derviaux, P Roche, A Restouin, MJ Basse, ...
ACS chemical biology 11 (8), 2140-2148, 2016
Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis
V Point, A Bénarouche, J Zarrillo, A Guy, R Magnez, L Fonseca, B Raux, ...
European journal of medicinal chemistry 123, 834-848, 2016
Supported inhibitor for fishing lipases in complex biological media and mass spectrometry identification
V Delorme, B Raux, R Puppo, J Leclaire, JF Cavalier, S Marc, ...
Biochimie 107, 124-134, 2014
Xanthine derivative inhibitors of BET proteins
X Morelli, S Combes, JC Guillemot, S Betzi, Y Collette, P Roche, A Lugari, ...
US Patent 11,225,481, 2022
Développement d'inhibiteurs d'interaction protéine-protéine ciblant les protéines à bromodomaines: implications en épigénétique et dans le développement de cancers
B Raux
Aix-Marseille, 2017
Exploring Selectivity of the First Bromo and Extra-Terminal (BET) Bromodomain Inhibition
B Raux, Y Voitovich, C Derviaux, A Lugari, E Rebuffet, S Milhas, S Priet, ...
Chemistry-driven Hit-to-Lead Optimization
L Hoffer, YV Voitovich, B Raux, M Saez-Ayala, K Carrasco, C Muller, ...
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