Mechanisms and therapeutic implications of hypermutation in gliomas M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ... Nature 580 (7804), 517-523, 2020 | 450 | 2020 |
The nuclear envelope environment and its cancer connections KH Chow, RE Factor, KS Ullman Nature Reviews Cancer 12 (3), 196-209, 2012 | 383 | 2012 |
DNA damage-induced replication fork regression and processing in Escherichia coli J Courcelle, JR Donaldson, KH Chow, CT Courcelle Science 299 (5609), 1064-1067, 2003 | 298 | 2003 |
RecO acts with RecF and RecR to protect and maintain replication forks blocked by UV-induced DNA damage in Escherichia coli KH Chow, J Courcelle Journal of Biological Chemistry 279 (5), 3492-3496, 2004 | 124 | 2004 |
Nascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coli CT Courcelle, KH Chow, A Casey, J Courcelle Proceedings of the National Academy of Sciences 103 (24), 9154-9159, 2006 | 109 | 2006 |
S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma KH Chow, HJ Park, J George, K Yamamoto, AD Gallup, JH Graber, ... Cancer research 77 (19), 5360-5373, 2017 | 100 | 2017 |
miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma WC Zhang, JM Wells, KH Chow, H Huang, M Yuan, T Saxena, ... Nature metabolism 1 (4), 460-474, 2019 | 63 | 2019 |
Expression and function of ABCG2 and XIAP in glioblastomas IF Emery, A Gopalan, S Wood, K Chow, C Battelli, J George, H Blaszyk, ... Journal of neuro-oncology 133, 47-57, 2017 | 59 | 2017 |
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2 KH Chow, S Elgort, M Dasso, KS Ullman Nucleus 3 (4), 349-358, 2012 | 45 | 2012 |
Selective colonization ability of human fecal microbes in different mouse gut environments W Zhou, K Chow, E Fleming, J Oh The ISME Journal 13 (3), 805-823, 2019 | 42 | 2019 |
The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function KH Chow, S Elgort, M Dasso, MA Powers, KS Ullman Molecular biology of the cell 25 (1), 160-168, 2014 | 32 | 2014 |
RecBCD and RecJ/RecQ Initiate DNA Degradation on Distinct Substrates in UV-Irradiated Escherichia coli KH Chow, J Courcelle Radiation Research 168 (4), 499-506, 2007 | 31 | 2007 |
Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity KH Chow, DM Shin, MH Jenkins, EE Miller, DJ Shih, S Choi, BE Low, ... Cancer research 74 (17), 4864-4874, 2014 | 24 | 2014 |
FGFR-inhibitor-mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance Y Li, X Qiu, X Wang, H Liu, RC Geck, AK Tewari, T Xiao, A Font-Tello, ... Nature cell biology 23 (11), 1187-1198, 2021 | 23 | 2021 |
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models MA Stockslager, S Malinowski, M Touat, JC Yoon, J Geduldig, M Mirza, ... Cell Reports 37 (1), 2021 | 22 | 2021 |
Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition JJ Wilson, K Chow, NJ Labrie, JA Branca, TJ Sproule, BRA Perkins, ... Cancer biology & therapy 20 (2), 169-182, 2019 | 16 | 2019 |
VRK1 as a synthetic lethal target in VRK2 promoter–methylated cancers of the nervous system J So, NW Mabe, B Englinger, KH Chow, SM Moyer, S Yerrum, MC Trissal, ... JCI insight 7 (19), 2022 | 11 | 2022 |
Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment PM Szabo, A Vajdi, N Kumar, MY Tolstorukov, BJ Chen, R Edwards, ... Scientific Reports 13 (1), 3051, 2023 | 10 | 2023 |
Cross‐Reaction of Anti‐Simian Immunodeficiency Virus Envelope Protein Antibodies with Human Immunoglobulins LM Zigment‐Reed, CA Fairley, KH Chow, F Yucel, B Cirakoglu, ... Scandinavian journal of immunology 57 (3), 239-245, 2003 | 6 | 2003 |
Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma DS Potter, R Du, SR Bohl, KH Chow, KL Ligon, R Bueno, A Letai Nature Communications 14 (1), 2897, 2023 | 3 | 2023 |