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Kin-Hoe Chow
Kin-Hoe Chow
Sigilon Therapeutics, a wholly subsidiary of Eli Lilly and Company
Ingen verifierad e-postadress - Startsida
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Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ...
Nature 580 (7804), 517-523, 2020
4502020
The nuclear envelope environment and its cancer connections
KH Chow, RE Factor, KS Ullman
Nature Reviews Cancer 12 (3), 196-209, 2012
3832012
DNA damage-induced replication fork regression and processing in Escherichia coli
J Courcelle, JR Donaldson, KH Chow, CT Courcelle
Science 299 (5609), 1064-1067, 2003
2982003
RecO acts with RecF and RecR to protect and maintain replication forks blocked by UV-induced DNA damage in Escherichia coli
KH Chow, J Courcelle
Journal of Biological Chemistry 279 (5), 3492-3496, 2004
1242004
Nascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coli
CT Courcelle, KH Chow, A Casey, J Courcelle
Proceedings of the National Academy of Sciences 103 (24), 9154-9159, 2006
1092006
S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma
KH Chow, HJ Park, J George, K Yamamoto, AD Gallup, JH Graber, ...
Cancer research 77 (19), 5360-5373, 2017
1002017
miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma
WC Zhang, JM Wells, KH Chow, H Huang, M Yuan, T Saxena, ...
Nature metabolism 1 (4), 460-474, 2019
632019
Expression and function of ABCG2 and XIAP in glioblastomas
IF Emery, A Gopalan, S Wood, K Chow, C Battelli, J George, H Blaszyk, ...
Journal of neuro-oncology 133, 47-57, 2017
592017
Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2
KH Chow, S Elgort, M Dasso, KS Ullman
Nucleus 3 (4), 349-358, 2012
452012
Selective colonization ability of human fecal microbes in different mouse gut environments
W Zhou, K Chow, E Fleming, J Oh
The ISME Journal 13 (3), 805-823, 2019
422019
The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function
KH Chow, S Elgort, M Dasso, MA Powers, KS Ullman
Molecular biology of the cell 25 (1), 160-168, 2014
322014
RecBCD and RecJ/RecQ Initiate DNA Degradation on Distinct Substrates in UV-Irradiated Escherichia coli
KH Chow, J Courcelle
Radiation Research 168 (4), 499-506, 2007
312007
Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity
KH Chow, DM Shin, MH Jenkins, EE Miller, DJ Shih, S Choi, BE Low, ...
Cancer research 74 (17), 4864-4874, 2014
242014
FGFR-inhibitor-mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance
Y Li, X Qiu, X Wang, H Liu, RC Geck, AK Tewari, T Xiao, A Font-Tello, ...
Nature cell biology 23 (11), 1187-1198, 2021
232021
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models
MA Stockslager, S Malinowski, M Touat, JC Yoon, J Geduldig, M Mirza, ...
Cell Reports 37 (1), 2021
222021
Enhancing the efficacy of glycolytic blockade in cancer cells via RAD51 inhibition
JJ Wilson, K Chow, NJ Labrie, JA Branca, TJ Sproule, BRA Perkins, ...
Cancer biology & therapy 20 (2), 169-182, 2019
162019
VRK1 as a synthetic lethal target in VRK2 promoter–methylated cancers of the nervous system
J So, NW Mabe, B Englinger, KH Chow, SM Moyer, S Yerrum, MC Trissal, ...
JCI insight 7 (19), 2022
112022
Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment
PM Szabo, A Vajdi, N Kumar, MY Tolstorukov, BJ Chen, R Edwards, ...
Scientific Reports 13 (1), 3051, 2023
102023
Cross‐Reaction of Anti‐Simian Immunodeficiency Virus Envelope Protein Antibodies with Human Immunoglobulins
LM Zigment‐Reed, CA Fairley, KH Chow, F Yucel, B Cirakoglu, ...
Scandinavian journal of immunology 57 (3), 239-245, 2003
62003
Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma
DS Potter, R Du, SR Bohl, KH Chow, KL Ligon, R Bueno, A Letai
Nature Communications 14 (1), 2897, 2023
32023
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Artiklar 1–20