| Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks MJ Lee, SY Albert, AK Gardino, AM Heijink, PK Sorger, G MacBeath, ... Cell 149 (4), 780-794, 2012 | 731 | 2012 |
| The bromodomain protein Brd4 insulates chromatin from DNA damage signalling SR Floyd, ME Pacold, Q Huang, SM Clarke, FC Lam, IG Cannell, ... Nature 498 (7453), 246-250, 2013 | 339 | 2013 |
| A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways SW Morton, MJ Lee, D ZJ, EC Dreaden, E Siouve, KE Shopsowitz, ... Science Signaling 7 (ra44), 2014 | 217 | 2014 |
| Protein regulation in signal transduction MJ Lee, MB Yaffe Signal Transduction: Principles, Pathways, and Processes 1, 31-50, 2014 | 130 | 2014 |
| Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor MJ Lee, HG Dohlman Current Biology 18 (3), 211-215, 2008 | 107 | 2008 |
| Combined experimental and computational analysis of DNA damage signaling reveals context‐dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress AR Tentner, MJ Lee, GJ Ostheimer, LD Samson, DA Lauffenburger, ... Molecular systems biology 8 (1), 568, 2012 | 84 | 2012 |
| Differential regulation of G protein α subunit trafficking by mono-and polyubiquitination Y Wang, LA Marotti, MJ Lee, HG Dohlman Journal of Biological Chemistry 280 (1), 284-291, 2005 | 51 | 2005 |
| A poly (ethylene glycol) three-dimensional bone marrow hydrogel LE Jansen, H Kim, CL Hall, TP McCarthy, MJ Lee, SR Peyton Biomaterials 280, 121270, 2022 | 39* | 2022 |
| Drug antagonism and single-agent dominance result from differences in death kinetics R Richards, HR Schwartz, ME Honeywell, MS Stewart, P Cruz-Gordillo, ... Nature chemical biology 16 (7), 791-800, 2020 | 37* | 2020 |
| Tumor‐stroma interactions differentially alter drug sensitivity based on the origin of stromal cells BD Landry, T Leete, R Richards, P Cruz‐Gordillo, HR Schwartz, ... Molecular Systems Biology 14 (8), e8322, 2018 | 37 | 2018 |
| Cold Spring Harbor Perspect MJ Lee, MB Yaffe Biol 8 (1.10), 1101, 2016 | 36 | 2016 |
| G protein mono-ubiquitination by the Rsp5 ubiquitin ligase MP Torres, MJ Lee, F Ding, C Purbeck, B Kuhlman, NV Dokholyan, ... Journal of biological chemistry 284 (13), 8940-8950, 2009 | 36 | 2009 |
| Modeling of cisplatin-induced signaling dynamics in triple-negative breast cancer cells reveals mediators of sensitivity AM Heijink, M Everts, ME Honeywell, R Richards, YP Kok, EGE de Vries, ... Cell reports 28 (9), 2345-2357. e5, 2019 | 30 | 2019 |
| Beclin 1 promotes endosome recruitment of hepatocyte growth factor tyrosine kinase substrate to suppress tumor proliferation AN Matthew-Onabanjo, J Janusis, J Mercado-Matos, AE Carlisle, D Kim, ... Cancer research 80 (2), 249-262, 2020 | 24 | 2020 |
| Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles HR Schwartz, R Richards, RE Fontana, AJ Joyce, ME Honeywell, MJ Lee Cell Reports 31 (12), 107800, 2020 | 22 | 2020 |
| ELP-dependent expression of MCL1 promotes resistance to EGFR inhibition in triple-negative breast cancer cells P Cruz-Gordillo, ME Honeywell, NW Harper, T Leete, MJ Lee Science signaling 13 (658), eabb9820, 2020 | 19 | 2020 |
| FLICK: an optimized plate reader-based assay to infer cell death kinetics R Richards, ME Honeywell, MJ Lee STAR protocols 2 (1), 100327, 2021 | 12 | 2021 |
| Compositions and methods of treatment of drug resistant cancers MB Yaffe, MJ Lee, PT Hammond, SW Morton US Patent 9,320,750, 2016 | 10 | 2016 |
| Bacterial diet modulates tamoxifen-induced death via host fatty acid metabolism C Diot, AP García-González, AF Vieira, M Walker, M Honeywell, H Doyle, ... Nature Communications 13 (1), 5595, 2022 | 9 | 2022 |
| Studying cellular signal transduction with OMIC technologies BD Landry, DC Clarke, MJ Lee Journal of molecular biology 427 (21), 3416-3440, 2015 | 9 | 2015 |
