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Yu Feng
Yu Feng
International AIDS Vaccine Initiative
Verifierad e-postadress på iavi.org
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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
X Wu, ZY Yang, Y Li, CM Hogerkorp, WR Schief, MS Seaman, T Zhou, ...
Science 329 (5993), 856-861, 2010
20182010
Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals
L Ni, F Ye, ML Cheng, Y Feng, YQ Deng, H Zhao, P Wei, J Ge, M Gou, ...
Immunity 52 (6), 971-977. e3, 2020
12342020
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ...
Nature 515 (7525), 138-142, 2014
5052014
Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01
Y Li, S O'Dell, LM Walker, X Wu, J Guenaga, Y Feng, SD Schmidt, ...
Journal of virology 85 (17), 8954-8967, 2011
2822011
Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design
SK Sharma, N de Val, S Bale, J Guenaga, K Tran, Y Feng, V Dubrovskaya, ...
Cell reports 11 (4), 539-550, 2015
2382015
PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4
E Falkowska, A Ramos, Y Feng, T Zhou, S Moquin, LM Walker, X Wu, ...
Journal of virology 86 (8), 4394-4403, 2012
1442012
Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
C Sundling, MNE Forsell, S O'Dell, Y Feng, B Chakrabarti, SS Rao, K Loré, ...
Journal of Experimental Medicine 207 (9), 2003-2017, 2010
1292010
High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site
C Sundling, Y Li, N Huynh, C Poulsen, R Wilson, S O’Dell, Y Feng, ...
Science translational medicine 4 (142), 142ra96-142ra96, 2012
1272012
Vaccination with glycan-modified HIV NFL envelope trimer-liposomes elicits broadly neutralizing antibodies to multiple sites of vulnerability
V Dubrovskaya, K Tran, G Ozorowski, J Guenaga, R Wilson, S Bale, ...
Immunity 51 (5), 915-929. e7, 2019
1222019
Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties
J Guenaga, N de Val, K Tran, Y Feng, K Satchwell, AB Ward, RT Wyatt
PLoS pathogens 11 (1), e1004570, 2015
1112015
Thermostability of well-ordered HIV spikes correlates with the elicitation of autologous tier 2 neutralizing antibodies
Y Feng, K Tran, S Bale, S Kumar, J Guenaga, R Wilson, N de Val, ...
PLoS pathogens 12 (8), e1005767, 2016
862016
Virus-like particles identify an HIV V1V2 apex-binding neutralizing antibody that lacks a protruding loop
EM Cale, J Gorman, NA Radakovich, ET Crooks, K Osawa, T Tong, J Li, ...
Immunity 46 (5), 777-791. e10, 2017
842017
Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates
BK Chakrabarti, Y Feng, SK Sharma, K McKee, GB Karlsson Hedestam, ...
Journal of virology 87 (24), 13239-13251, 2013
772013
Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding site
Y Feng, K McKee, K Tran, S O'Dell, SD Schmidt, A Phogat, MN Forsell, ...
Journal of Biological Chemistry 287 (8), 5673-5686, 2012
612012
Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates
I Douagi, MNE Forsell, C Sundling, S O'Dell, Y Feng, P Dosenovic, Y Li, ...
Journal of virology 84 (4), 1683-1695, 2010
532010
Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response
V Dubrovskaya, J Guenaga, N de Val, R Wilson, Y Feng, A Movsesyan, ...
PLoS pathogens 13 (9), e1006614, 2017
482017
Characterization of anti-viral immunity in recovered individuals infected by SARS-CoV-2
L Ni, F Ye, ML Chen, Y Feng, YQ Deng, H Zhao, P Wei, J Ge, X Li, L Sun, ...
MedRxiv, 2020.03. 17.20036640, 2020
432020
Impaired cellular immunity to SARS-CoV-2 in severe COVID-19 patients
L Ni, ML Cheng, Y Feng, H Zhao, J Liu, F Ye, Q Ye, G Zhu, X Li, P Wang, ...
Frontiers in immunology 12, 603563, 2021
412021
Analysis of VISTA expression and function in renal cell carcinoma highlights VISTA as a potential target for immunotherapy
S Hong, Q Yuan, H Xia, G Zhu, Y Feng, Q Wang, Z Zhang, W He, J Lu, ...
Protein & Cell 10 (11), 840-845, 2019
402019
Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization
GE Phad, N Vázquez Bernat, Y Feng, J Ingale, PA Martinez Murillo, ...
The Journal of Immunology 194 (12), 5903-5914, 2015
342015
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Artiklar 1–20