| antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters T Weber, K Blin, S Duddela, D Krug, HU Kim, R Bruccoleri, SY Lee, ... Nucleic acids research 43 (W1), W237-W243, 2015 | 1643 | 2015 |
| antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences MH Medema, K Blin, P Cimermancic, V de Jager, P Zakrzewski, ... Nucleic acids research 39 (suppl_2), W339-W346, 2011 | 1230 | 2011 |
| antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification K Blin, T Wolf, MG Chevrette, X Lu, CJ Schwalen, SA Kautsar, ... Nucleic acids research 45 (W1), W36-W41, 2017 | 828 | 2017 |
| antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers K Blin, MH Medema, D Kazempour, MA Fischbach, R Breitling, E Takano, ... Nucleic acids research 41 (W1), W204-W212, 2013 | 805 | 2013 |
| Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters P Cimermancic, MH Medema, J Claesen, K Kurita, LCW Brown, ... Cell 158 (2), 412-421, 2014 | 572 | 2014 |
| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 485 | 2015 |
| γ-Butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation E Takano Current opinion in microbiology 9 (3), 287-294, 2006 | 356 | 2006 |
| A complex role for the γ‐butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2) E Takano, R Chakraburtty, T Nihira, Y Yamada, MJ Bibb Molecular microbiology 41 (5), 1015-1028, 2001 | 259 | 2001 |
| Transcriptional regulation of the redD transcriptional activator gene accounts for growth‐phase‐dependent production of the antibiotic undecylprodigiosin in Streptomyces … E Takano, HC Gramajo, E Strauch, N Andres, J White, MJ Bibb Molecular microbiology 6 (19), 2797-2804, 1992 | 237 | 1992 |
| Detecting sequence homology at the gene cluster level with MultiGeneBlast MH Medema, E Takano, R Breitling Molecular biology and evolution 30 (5), 1218-1223, 2013 | 230 | 2013 |
| Stationary‐phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated HC Gramajo, E Takano, MJ Bibb Molecular microbiology 7 (6), 837-845, 1993 | 230 | 1993 |
| Computational tools for the synthetic design of biochemical pathways MH Medema, R Van Raaphorst, E Takano, R Breitling Nature Reviews Microbiology 10 (3), 191-202, 2012 | 220 | 2012 |
| The stringent response in Streptomyces coelicolor A3(2) E Strauch, E Takano, HA Baylts, MJ Bibb Molecular microbiology 5 (2), 289-298, 1991 | 211 | 1991 |
| The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways MH Medema, A Trefzer, A Kovalchuk, M van den Berg, U Müller, W Heijne, ... Genome Biology and Evolution 2, 212-224, 2010 | 190 | 2010 |
| Purification and Structural Determination of SCB1, a γ-Butyrolactone That Elicits Antibiotic Production inStreptomyces coelicolor A3 (2) E Takano, T Nihira, Y Hara, JJ Jones, CJL Gershater, Y Yamada, M Bibb Journal of Biological Chemistry 275 (15), 11010-11016, 2000 | 190 | 2000 |
| Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms MH Medema, R Breitling, R Bovenberg, E Takano Nature Reviews Microbiology 9 (2), 131-137, 2011 | 181 | 2011 |
| A bacterial hormone (the SCB1) directly controls the expression of a pathway‐specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces … E Takano, H Kinoshita, V Mersinias, G Bucca, G Hotchkiss, T Nihira, ... Molecular microbiology 56 (2), 465-479, 2005 | 173 | 2005 |
| The dynamic architecture of the metabolic switch in Streptomyces coelicolor K Nieselt, F Battke, A Herbig, P Bruheim, A Wentzel, ØM Jakobsen, ... BMC genomics 11 (1), 10, 2010 | 165 | 2010 |
| The dynamic architecture of the metabolic switch in Streptomyces coelicolor N Kay, B Florian, H Alexander, B Per, W Alexander, J Øyvind, S Håvard, ... BMC Genomics 11, 2010 | 165 | 2010 |
| Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3 (2) M Gottelt, S Kol, JP Gomez-Escribano, M Bibb, E Takano Microbiology 156 (8), 2343-2353, 2010 | 163 | 2010 |
Rainer BreitlingProfessor of Systems Biology, Manchester Institute of Biotechnology, University of ManchesterVerified email at manchester.ac.uk
