Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases FL Cherblanc, KL Chapman, R Brown, MJ Fuchter Nature chemical biology 9 (3), 136-137, 2013 | 104 | 2013 |
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells E Curry, I Green, N Chapman-Rothe, E Shamsaei, S Kandil, FL Cherblanc, ... Clinical epigenetics 7, 1-12, 2015 | 72 | 2015 |
Perspectives on natural product epigenetic modulators in chemical biology and medicine FL Cherblanc, RWM Davidson, P Di Fruscia, N Srimongkolpithak, ... Natural Product Reports 30 (5), 605-624, 2013 | 63 | 2013 |
On the histone lysine methyltransferase activity of fungal metabolite chaetocin FL Cherblanc, KL Chapman, J Reid, AJ Borg, S Sundriyal, L Alcazar-Fuoli, ... Journal of medicinal chemistry 56 (21), 8616-8625, 2013 | 60 | 2013 |
Current limitations and future opportunities for epigenetic therapies F Cherblanc, N Chapman-Rothe, R Brown, MJ Fuchter Future medicinal chemistry 4 (4), 425-446, 2012 | 48 | 2012 |
On the determination of the stereochemistry of semisynthetic natural product analogues using chiroptical spectroscopy: desulfurization of epidithiodioxopiperazine fungal … F Cherblanc, YP Lo, E De Gussem, L Alcazar‐Fuoli, E Bignell, Y He, ... Chemistry–A European Journal 17 (42), 11868-11875, 2011 | 32 | 2011 |
Mechanistic and chiroptical studies on the desulfurization of epidithiodioxopiperazines reveal universal retention of configuration at the bridgehead carbon atoms FL Cherblanc, YP Lo, WA Herrebout, P Bultinck, HS Rzepa, MJ Fuchter The Journal of Organic Chemistry 78 (23), 11646-11655, 2013 | 20 | 2013 |
Chiroptical studies on brevianamide B: Vibrational and electronic circular dichroism confronted P Bultinck, FL Cherblanc, MJ Fuchter, WA Herrebout, YP Lo, HS Rzepa, ... The Journal of Organic Chemistry 80 (7), 3359-3367, 2015 | 11 | 2015 |
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells. Clin Epigenetics 7: 84 E Curry, I Green, N Chapman-Rothe, E Shamsaei, S Kandil, FL Cherblanc, ... | 7 | 2015 |
554 Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells R Brown, M Fuchter, E Curry, I Green, S Kandil, F Cherblanc, L Payne, ... European Journal of Cancer, 179-180, 2014 | 1 | 2014 |
Synthesis and biological evaluation of histone lysine methyltransferase inhibitors F Cherblanc Imperial College London, 2013 | | 2013 |