Current status on prevention and treatment of canine leishmaniasis RM Reguera, M Moran, Y Perez-Pertejo, C Garcia-Estrada, ... Veterinary parasitology 227, 98-114, 2016 | 158 | 2016 |
A novel active DNA topoisomerase I in Leishmania donovani H Villa, ARO Marcos, RM Reguera, R Balana-Fouce, C Garcıa-Estrada, ... Journal of Biological Chemistry 278 (6), 3521-3526, 2003 | 100 | 2003 |
Role of trypanosomatid's arginase in polyamine biosynthesis and pathogenesis R Balaña-Fouce, E Calvo-Álvarez, R Álvarez-Velilla, CF Prada, ... Molecular and biochemical parasitology 181 (2), 85-93, 2012 | 80 | 2012 |
Infrared Fluorescent Imaging as a Potent Tool for In Vitro, Ex Vivo and In Vivo Models of Visceral Leishmaniasis E Calvo-Alvarez, K Stamatakis, C Punzón, R Alvarez-Velilla, A Tejeria, ... PLoS neglected tropical diseases 9 (3), e0003666, 2015 | 78 | 2015 |
DNA topoisomerase I from parasitic protozoa: a potential target for chemotherapy RM Reguera, CM Redondo, RG De Prado, Y Pérez-Pertejo, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1759 (3-4 …, 2006 | 71 | 2006 |
Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect CF Prada, R Alvarez-Velilla, R Balana-Fouce, C Prieto, E Calvo-Alvarez, ... Biochemical pharmacology 85 (10), 1433-1440, 2013 | 64 | 2013 |
Alterations of the glutathione–redox balance induced by metals in CHO-K1 cells AJ Garcıa-Fernandez, AE Bayoumi, Y Pérez-Pertejo, M Motas, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2002 | 63 | 2002 |
Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine … E Calvo-Alvarez, NA Guerrero, R Alvarez-Velilla, CF Prada, JM Requena, ... PLoS neglected tropical diseases 6 (11), e1927, 2012 | 61 | 2012 |
Targeting atypical trypanosomatid DNA topoisomerase I R Balaña-Fouce, CM Redondo, Y Pérez-Pertejo, R Díaz-González, ... Drug Discovery Today 11 (15-16), 733-740, 2006 | 61 | 2006 |
Indotecan (LMP400) and AM13-55: two novel indenoisoquinolines show potential for treating visceral leishmaniasis R Balaña-Fouce, CF Prada, JM Requena, M Cushman, Y Pommier, ... Antimicrobial agents and chemotherapy 56 (10), 5264-5270, 2012 | 59 | 2012 |
Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents A Tejeria, Y Perez-Pertejo, RM Reguera, R Carbajo-Andres, ... European journal of medicinal chemistry 162, 18-31, 2019 | 55 | 2019 |
Antileishmanial effect of new indeno-1, 5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase A Tejeria, Y Perez-Pertejo, RM Reguera, R Balana-Fouce, C Alonso, ... European Journal of Medicinal Chemistry 124, 740-749, 2016 | 54 | 2016 |
Screening marine natural products for new drug leads against trypanosomatids and malaria M Álvarez-Bardón, Y Pérez-Pertejo, C Ordóñez, D Sepúlveda-Crespo, ... Marine Drugs 18 (4), 187, 2020 | 53 | 2020 |
Cloning Expression and Characterization of Methionine Adenosyltransferase in Leishmania infantumPromastigotes RM Reguera, R Balana-Fouce, Y Pérez-Pertejo, FJ Fernández, ... Journal of Biological Chemistry 277 (5), 3158-3167, 2002 | 51 | 2002 |
S-Adenosylmethionine in protozoan parasites: functions, synthesis and regulation RM Reguera, CM Redondo, Y Pérez-Pertejo, R Balana-Fouce Molecular and biochemical parasitology 152 (1), 1-10, 2007 | 48 | 2007 |
Current and promising novel drug candidates against visceral leishmaniasis RM Reguera, Y Pérez-Pertejo, C Gutiérrez-Corbo, B Domínguez-Asenjo, ... Pure and Applied Chemistry 91 (8), 1385-1404, 2019 | 46 | 2019 |
First Evidence of Intraclonal Genetic Exchange in Trypanosomatids Using Two Leishmania infantum Fluorescent Transgenic Clones E Calvo-Alvarez, R Alvarez-Velilla, M Jimenez, R Molina, Y Perez-Pertejo, ... PLoS Neglected Tropical Diseases 8 (9), e3075, 2014 | 43 | 2014 |
Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani H Villa, Y Pérez‐Pertejo, C García‐Estrada, RM Reguera, JM Requena, ... European Journal of Biochemistry 270 (21), 4339-4347, 2003 | 41 | 2003 |
Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum JM Escudero-Martínez, Y Pérez-Pertejo, RM Reguera, MÁ Castro, ... International Journal for Parasitology: Drugs and Drug Resistance 7 (3), 272-285, 2017 | 36 | 2017 |
Cytotoxic effects of two antimolting insecticides in mammalian CHO-K1 cells AE Bayoumi, Y Pérez-Pertejo, HZ Zidan, R Balaña-Fouce, C Ordóñez, ... Ecotoxicology and environmental safety 55 (1), 19-23, 2003 | 34 | 2003 |