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Webster L. Santos
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Copper-boryl mediated organic synthesis
D Hemming, R Fritzemeier, SA Westcott, WL Santos, PG Steel
Chemical Society Reviews 47 (19), 7477-7494, 2018
2462018
Structure of a DNA glycosylase searching for lesions
A Banerjee, WL Santos, GL Verdine
Science 311 (5764), 1153-1157, 2006
2352006
Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane
BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ...
Molecular metabolism 3 (2), 114-123, 2014
2322014
sp2−sp3 Hybridized Mixed Diboron: Synthesis, Characterization, and Copper-Catalyzed β-Boration of α,β-Unsaturated Conjugated Compounds
M Gao, SB Thorpe, WL Santos
Organic Letters 11 (15), 3478-3481, 2009
1672009
Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent
SB Hooks, WL Santos, DS Im, CE Heise, TL Macdonald, KR Lynch
Journal of Biological Chemistry 276 (7), 4611-4621, 2001
1652001
First-row d-block element-catalyzed carbon–boron bond formation and related processes
SK Bose, L Mao, L Kuehn, U Radius, J Nekvinda, WL Santos, SA Westcott, ...
Chemical Reviews 121 (21), 13238-13341, 2021
1622021
Activity of 2-Substituted Lysophosphatidic Acid (LPA) Analogs at LPA Receptors: Discovery of a LPA1/LPA3Receptor Antagonist
CE Heise, WL Santos, AM Schreihofer, BH Heasley, YV Mukhin, ...
Molecular Pharmacology 60 (6), 1173-1180, 2001
1372001
Structure and Reactivity of a Preactivated sp2–sp3 Diboron Reagent: Catalytic Regioselective Boration of α,β-Unsaturated Conjugated Compounds
M Gao, SB Thorpe, C Kleeberg, C Slebodnick, TB Marder, WL Santos
The Journal of Organic Chemistry 76 (10), 3997-4007, 2011
1322011
Small molecule mitochondrial uncouplers and their therapeutic potential: miniperspective
ES Childress, SJ Alexopoulos, KL Hoehn, WL Santos
Journal of Medicinal Chemistry 61 (11), 4641-4655, 2017
1292017
Regio-and stereoselective copper-catalyzed β-borylation of allenoates by a preactivated diboron
SB Thorpe, X Guo, WL Santos
Chemical communications 47 (1), 424-426, 2011
1162011
Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate
Y Kharel, M Raje, M Gao, AM Gellett, JL Tomsig, KR Lynch, WL Santos
Biochemical Journal 447 (1), 149-157, 2012
1042012
Integration requires a specific interaction of the donor DNA terminal 5′-cytosine with glutamine 148 of the HIV-1 integrase flexible loop
AA Johnson, W Santos, GCG Pais, C Marchand, R Amin, TR Burke, ...
Journal of Biological Chemistry 281 (1), 461-467, 2006
952006
Drugging sphingosine kinases
WL Santos, KR Lynch
ACS chemical biology 10 (1), 225-233, 2015
922015
Unexpected copper (II) catalysis: Catalytic amine base promoted β-borylation of α, β-unsaturated carbonyl compounds in water
SB Thorpe, JA Calderone, WL Santos
Organic Letters 14 (7), 1918-1921, 2012
892012
A method for the deprotection of alkylpinacolyl boronate esters
J Sun, MT Perfetti, WL Santos
The Journal of organic chemistry 76 (9), 3571-3575, 2011
802011
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice
SJ Alexopoulos, SY Chen, AE Brandon, JM Salamoun, FL Byrne, ...
Nature Communications 11 (1), 2397, 2020
792020
Structure− activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of sphK1-and sphK2-selective inhibitors
NN Patwardhan, EA Morris, Y Kharel, MR Raje, M Gao, JL Tomsig, ...
Journal of medicinal chemistry 58 (4), 1879-1899, 2015
762015
Copper(II)‐Catalyzed Silylation of Activated Alkynes in Water: Diastereodivergent Access to E‐ or Z‐β‐Silyl‐α,β‐Unsaturated Carbonyl and Carboxyl Compounds
JA Calderone, WL Santos
Angewandte Chemie International Edition 53 (16), 4154-4158, 2014
722014
Substrate‐Assisted, Transition‐Metal‐Free Diboration of Alkynamides with Mixed Diboron: Regio‐ and Stereoselective Access to trans‐1,2‐Vinyldiboronates
A Verma, RF Snead, Y Dai, C Slebodnick, Y Yang, H Yu, F Yao, ...
Angewandte Chemie 129 (18), 5193-5197, 2017
692017
Sphingosine kinase 2 inhibition and blood sphingosine 1-phosphate levels
Y Kharel, EA Morris, MD Congdon, SB Thorpe, JL Tomsig, WL Santos, ...
Journal of Pharmacology and Experimental Therapeutics 355 (1), 23-31, 2015
692015
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Artiklar 1–20