| Autophagy mediates the mitotic senescence transition ARJ Young, M Narita, M Ferreira, K Kirschner, M Sadaie, JFJ Darot, ... Genes & development 23 (7), 798-803, 2009 | 862 | 2009 |
| SC3: consensus clustering of single-cell RNA-seq data VY Kiselev, K Kirschner, MT Schaub, T Andrews, A Yiu, T Chandra, ... Nature methods 14 (5), 483-486, 2017 | 574 | 2017 |
| Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation T Chandra, K Kirschner, JY Thuret, BD Pope, T Ryba, S Newman, ... Molecular cell 47 (2), 203-214, 2012 | 205 | 2012 |
| Global reorganization of the nuclear landscape in senescent cells T Chandra, PA Ewels, S Schoenfelder, M Furlan-Magaril, SW Wingett, ... Cell reports 10 (4), 471-483, 2015 | 178 | 2015 |
| Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs K Kirschner, DW Melton Anticancer research 30 (9), 3223-3232, 2010 | 127 | 2010 |
| Amplification of HSD17B1 and ERBB2 in primary breast cancer C Gunnarsson, M Ahnström, K Kirschner, B Olsson, B Nordenskjöld, ... Oncogene 22 (1), 34-40, 2003 | 93 | 2003 |
| Latent regulatory potential of human-specific repetitive elements MC Ward, MD Wilson, NL Barbosa-Morais, D Schmidt, R Stark, Q Pan, ... Molecular cell 49 (2), 262-272, 2013 | 66 | 2013 |
| Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion DG Kent, J Li, H Tanna, J Fink, K Kirschner, DC Pask, Y Silber, ... PLoS Biol 11 (6), e1001576, 2013 | 55 | 2013 |
| Cytokine‐induced megakaryocytic differentiation is regulated by genome‐wide loss of a uSTAT transcriptional program HJ Park, J Li, R Hannah, S Biddie, AI Leal‐Cervantes, K Kirschner, ... The EMBO journal 35 (6), 580-594, 2016 | 51 | 2016 |
| Experimental design for single-cell RNA sequencing J Baran-Gale, T Chandra, K Kirschner Briefings in functional genomics 17 (4), 233-239, 2018 | 44 | 2018 |
| Proliferation drives aging-related functional decline in a subpopulation of the hematopoietic stem cell compartment K Kirschner, T Chandra, V Kiselev, D Flores-Santa Cruz, IC Macaulay, ... Cell reports 19 (8), 1503-1511, 2017 | 37 | 2017 |
| Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53 Plos Genetics, 2015 | 36 | 2015 |
| Chromosome organisation during ageing and senescence T Chandra, K Kirschner Current Opinion in Cell Biology 40, 161-167, 2016 | 33 | 2016 |
| Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress R Burt, A Dey, S Aref, M Aguiar, A Akarca, K Bailey, W Day, S Hooper, ... Blood 134 (17), 1415-1429, 2019 | 18 | 2019 |
| Notch signaling mediates secondary senescence YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ... Cell reports 27 (4), 997-1007. e5, 2019 | 16 | 2019 |
| Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro K Kirschner, R Singh, S Prost, DW Melton DNA repair 6 (3), 304-316, 2007 | 14 | 2007 |
| Age-related clonal haemopoiesis is associated with increased epigenetic age NA Robertson, RF Hillary, DL McCartney, M Terradas-Terradas, J Higham, ... Current Biology 29 (16), R786-R787, 2019 | 9 | 2019 |
| Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis S Alivernini, L MacDonald, A Elmesmari, S Finlay, B Tolusso, MR Gigante, ... Nature medicine 26 (8), 1295-1306, 2020 | 4 | 2020 |
| Expression of 17β-hydroxysteroid dehydrogenases and correlation to prognosis in postmenopausal breast cancer patients C Gunnarsson, K Kirschner, E Hellqvist, O Stål Breast Cancer Research and Treatment 82, 2003 | 4 | 2003 |
| Functional heterogeneity in senescence K Kirschner, N Rattanavirotkul, MF Quince, T Chandra Biochemical Society Transactions, BST20190109, 2020 | 2 | 2020 |
Tamir ChandraMRC Unit for Human Genetics, IGMM EdinburghVerified email at igmm.ed.ac.uk
