Lutz Jermutus
Lutz Jermutus
Verified email at medimmune.com
Title
Cited by
Cited by
Year
Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries
J Hanes, L Jermutus, S Weber-Bornhauser, HR Bosshard, A Plückthun
Proceedings of the National Academy of Sciences 95 (24), 14130-14135, 1998
4341998
Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation rates
F Schwesinger, R Ros, T Strunz, D Anselmetti, HJ Güntherodt, ...
Proceedings of the National Academy of Sciences 97 (18), 9972-9977, 2000
3742000
Tailoring in vitro evolution for protein affinity or stability
L Jermutus, A Honegger, F Schwesinger, J Hanes, A Plückthun
Proceedings of the National Academy of Sciences 98 (1), 75-80, 2001
3272001
Tailoring in vitro evolution for protein affinity or stability
L Jermutus, A Honegger, F Schwesinger, J Hanes, A Plückthun
Proceedings of the National Academy of Sciences 98 (1), 75-80, 2001
3272001
Ribosome display: an in vitro method for selection and evolution of antibodies from libraries
C Schaffitzel, J Hanes, L Jermutus, A Plückthun
Journal of immunological methods 231 (1-2), 119-135, 1999
3211999
Ribosome display: an in vitro method for selection and evolution of antibodies from libraries
C Schaffitzel, J Hanes, L Jermutus, A Plückthun
Journal of immunological methods 231 (1-2), 119-135, 1999
3211999
Recent advances in producing and selecting functional proteins by using cell-free translation
L Jermutus, LA Ryabova, A Plückthun
Current Opinion in Biotechnology 9 (5), 534-548, 1998
2561998
Challenges and opportunities for non-antibody scaffold drugs
R Vazquez-Lombardi, TG Phan, C Zimmermann, D Lowe, L Jermutus, ...
Drug discovery today 20 (10), 1271-1283, 2015
1822015
Concepts in antibody phage display
S Carmen, L Jermutus
Briefings in Functional Genomics 1 (2), 189-203, 2002
1822002
Harnessing phage and ribosome display for antibody optimisation
P Dufner, L Jermutus, RR Minter
Trends in biotechnology 24 (11), 523-529, 2006
1532006
[24] Selecting and evolving functional proteins in vitro by ribosome display
J Hanes, L Jermutus, A Plückthun
Methods in enzymology 328, 404-430, 2000
1482000
Aggregation, stability, and formulation of human antibody therapeutics
D Lowe, K Dudgeon, R Rouet, P Schofield, L Jermutus, D Christ
Advances in protein chemistry and structural biology 84, 41-61, 2011
1472011
Selection of hapten-specific single-domain antibodies from a non-immunized llama ribosome display library
KYF Yau, MAT Groves, S Li, C Sheedy, H Lee, J Tanha, CR MacKenzie, ...
Journal of immunological methods 281 (1-2), 161-175, 2003
1282003
Robust anti‐obesity and metabolic effects of a dual GLP‐1/glucagon receptor peptide agonist in rodents and non‐human primates
SJ Henderson, A Konkar, DC Hornigold, JL Trevaskis, R Jackson, ...
Diabetes, Obesity and Metabolism 18 (12), 1176-1190, 2016
1242016
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a …
P Ambery, VE Parker, M Stumvoll, MG Posch, T Heise, L Plum-Moerschel, ...
The Lancet 391 (10140), 2607-2618, 2018
1162018
In vitro selection and evolution of proteins
A Plückthun, C Schaffitzel, J Hanes, L Jermutus
Advances in protein chemistry 55, 367-403, 2001
1162001
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening
A DiGiandomenico, P Warrener, M Hamilton, S Guillard, P Ravn, R Minter, ...
Journal of Experimental Medicine 209 (7), 1273-1287, 2012
1122012
Probing a protein–protein interaction by in vitro evolution
G Thom, AC Cockroft, AG Buchanan, CJ Candotti, ES Cohen, D Lowne, ...
Proceedings of the National Academy of Sciences 103 (20), 7619-7624, 2006
1022006
In vitro selection for catalytic activity with ribosome display
P Amstutz, JN Pelletier, A Guggisberg, L Jermutus, S Cesaro-Tadic, ...
Journal of the American Chemical Society 124 (32), 9396-9403, 2002
962002
Comparison of Escherichia coli and rabbit reticulocyte ribosome display systems
J Hanes, L Jermutus, C Schaffitzel, A Plückthun
FEBS letters 450 (1-2), 105-110, 1999
941999
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