Regulation and mechanisms of mammalian double-strand break repair K Valerie, LF Povirk Oncogene 22 (37), 5792-5812, 2003 | 828 | 2003 |
Stress and radiation-induced activation of multiple intracellular signaling pathways P Dent, A Yacoub, J Contessa, R Caron, G Amorino, K Valerie, MP Hagan, ... Radiation research 159 (3), 283-300, 2003 | 633 | 2003 |
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation RK Schmidt-Ullrich, RB Mikkelsen, P Dent, DG Todd, K Valerie, ... Oncogene 15 (10), 1191-1197, 1997 | 526 | 1997 |
mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 … D Sarkar, ZZ Su, IV Lebedeva, M Sauane, RV Gopalkrishnan, K Valerie, ... Proceedings of the National Academy of Sciences 99 (15), 10054-10059, 2002 | 439 | 2002 |
Radiation-induced release of transforming growth factor α activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells … P Dent, DB Reardon, JS Park, G Bowers, C Logsdon, K Valerie, ... Molecular biology of the cell 10 (8), 2493-2506, 1999 | 433 | 1999 |
Signal transduction and cellular radiation responses RK Schmidt-Ullrich, P Dent, S Grant, RB Mikkelsen, K Valerie Radiation research 153 (3), 245-257, 2000 | 415 | 2000 |
Radiation-induced cell signaling: inside-out and outside-in K Valerie, A Yacoub, MP Hagan, DT Curiel, PB Fisher, S Grant, P Dent Molecular cancer therapeutics 6 (3), 789-801, 2007 | 412 | 2007 |
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion SE Golding, E Rosenberg, N Valerie, I Hussaini, M Frigerio, XF Cockcroft, ... Molecular cancer therapeutics 8 (10), 2894-2902, 2009 | 387 | 2009 |
Activation of the nuclear factor κB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis L Emdad, D Sarkar, Z Su, A Randolph, H Boukerche, K Valerie, PB Fisher Cancer research 66 (3), 1509-1516, 2006 | 369 | 2006 |
Activation of human immunodeficiency virus type 1 by DNA damage in human cells K Valerie, A Delers, C Bruck, C Thiriart, H Rosenberg, C Debouck, ... Nature 333 (6168), 78-81, 1988 | 300 | 1988 |
Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen … L Qiao, E Studer, K Leach, R McKinstry, S Gupta, R Decker, R Kukreja, ... Molecular biology of the cell 12 (9), 2629-2645, 2001 | 272 | 2001 |
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene D Kang, RV Gopalkrishnan, L Lin, A Randolph, K Valerie, S Pestka, ... Oncogene 23 (9), 1789-1800, 2004 | 271 | 2004 |
BLM helicase‐dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination S Sengupta, SP Linke, R Pedeux, Q Yang, J Farnsworth, SH Garfield, ... The EMBO journal, 2003 | 260 | 2003 |
Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner ZZ Su, IV Lebedeva, D Sarkar, RV Gopalkrishnan, M Sauane, C Sigmon, ... Oncogene 22 (8), 1164-1180, 2003 | 244 | 2003 |
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models ST Durant, L Zheng, Y Wang, K Chen, L Zhang, T Zhang, Z Yang, ... Science advances 4 (6), eaat1719, 2018 | 235 | 2018 |
Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells SE Golding, RN Morgan, BR Adams, AJ Hawkins, LF Povirk, K Valerie Cancer biology & therapy 8 (8), 730-738, 2009 | 223 | 2009 |
ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation L Biddlestone-Thorpe, M Sajjad, E Rosenberg, JM Beckta, NCK Valerie, ... Clinical Cancer Research 19 (12), 3189-3200, 2013 | 210 | 2013 |
The relative role of ErbB1–4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells G Bowers, D Reardon, T Hewitt, P Dent, RB Mikkelsen, K Valerie, ... Oncogene 20 (11), 1388-1397, 2001 | 206 | 2001 |
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response SE Golding, E Rosenberg, S Neill, P Dent, LF Povirk, K Valerie Cancer research 67 (3), 1046-1053, 2007 | 205 | 2007 |
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells JN Contessa, J Hampton, G Lammering, RB Mikkelsen, P Dent, K Valerie, ... Oncogene 21 (25), 4032-4041, 2002 | 199 | 2002 |